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  5. AAC77190

AAC77190 (mpl, b4233)


Aliases : mpl, b4233

Description : UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [Ensembl]. Mur ligase family, Mur ligase middle domain [Interproscan].


Gene families : OG_02_0000198 (OrthoFinder) Phylogenetic Tree(s): OG0000198_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAC77190
Cluster HCCA: Cluster_47

Target Alias Description ECC score Gene Family Method Actions
AAL23236 STM4416, mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diami... 0.16 OrthoFinder
AGT25947 N559_4334 UDP-N-acetylmuramate--L-alanine ligase [Ensembl]. Mur... 0.05 OrthoFinder
AGT26264 N559_4670 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diami... 0.06 OrthoFinder
AKP14603 murC, WX61_00522 UDP-N-acetylmuramate--L-alanine ligase [Ensembl]. Mur... 0.03 OrthoFinder
AKP16137 mpl, WX61_02111 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diami... 0.02 OrthoFinder
CBI66379 murC, HPB8_822 UDP-N-acetylmuramate-alanine ligase (MurC) [Ensembl].... 0.02 OrthoFinder
CCG26428 No alias UDP-N-acetylmuramate--alanine ligase [Ensembl]. Mur... 0.03 OrthoFinder
CCP44928 murC, Rv2152c Probable UDP-N-acetylmuramate-alanine ligase MurC... 0.03 OrthoFinder
CRP42016 mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diami... 0.03 OrthoFinder
EDJ91943 murG, CGSHi22421_09308 N-acetylglucosaminyl transferase [Ensembl]. Mur ligase... 0.04 OrthoFinder
KNA53287 VCV51_031614 UDP-N-acetylmuramate-alanine ligase [Ensembl]. Mur... 0.1 OrthoFinder
KNA55023 VCV51_031716 L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase... 0.04 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0009058 biosynthetic process IEA Interproscan
MF GO:0016874 ligase activity IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0003690 double-stranded DNA binding IEP Enrichment
MF GO:0003916 DNA topoisomerase activity IEP Enrichment
MF GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004813 alanine-tRNA ligase activity IEP Enrichment
MF GO:0004814 arginine-tRNA ligase activity IEP Enrichment
MF GO:0004820 glycine-tRNA ligase activity IEP Enrichment
MF GO:0004853 uroporphyrinogen decarboxylase activity IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006265 DNA topological change IEP Enrichment
BP GO:0006323 DNA packaging IEP Enrichment
BP GO:0006396 RNA processing IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006419 alanyl-tRNA aminoacylation IEP Enrichment
BP GO:0006420 arginyl-tRNA aminoacylation IEP Enrichment
BP GO:0006426 glycyl-tRNA aminoacylation IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
BP GO:0006553 lysine metabolic process IEP Enrichment
BP GO:0006605 protein targeting IEP Enrichment
BP GO:0006612 protein targeting to membrane IEP Enrichment
BP GO:0006613 cotranslational protein targeting to membrane IEP Enrichment
BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006886 intracellular protein transport IEP Enrichment
BP GO:0006996 organelle organization IEP Enrichment
BP GO:0007059 chromosome segregation IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
MF GO:0008168 methyltransferase activity IEP Enrichment
MF GO:0008312 7S RNA binding IEP Enrichment
MF GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity IEP Enrichment
MF GO:0008837 diaminopimelate epimerase activity IEP Enrichment
BP GO:0009085 lysine biosynthetic process IEP Enrichment
BP GO:0009089 lysine biosynthetic process via diaminopimelate IEP Enrichment
CC GO:0009295 nucleoid IEP Enrichment
CC GO:0009349 riboflavin synthase complex IEP Enrichment
BP GO:0016043 cellular component organization IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
MF GO:0016831 carboxy-lyase activity IEP Enrichment
MF GO:0016849 phosphorus-oxygen lyase activity IEP Enrichment
MF GO:0016853 isomerase activity IEP Enrichment
MF GO:0016854 racemase and epimerase activity IEP Enrichment
MF GO:0016866 intramolecular transferase activity IEP Enrichment
MF GO:0016868 intramolecular transferase activity, phosphotransferases IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0016887 ATPase IEP Enrichment
MF GO:0019001 guanyl nucleotide binding IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
BP GO:0030261 chromosome condensation IEP Enrichment
MF GO:0030983 mismatched DNA binding IEP Enrichment
BP GO:0032324 molybdopterin cofactor biosynthetic process IEP Enrichment
MF GO:0032561 guanyl ribonucleotide binding IEP Enrichment
BP GO:0033365 protein localization to organelle IEP Enrichment
BP GO:0034613 cellular protein localization IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
BP GO:0043170 macromolecule metabolic process IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0045047 protein targeting to ER IEP Enrichment
BP GO:0046451 diaminopimelate metabolic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
BP GO:0046907 intracellular transport IEP Enrichment
MF GO:0047661 amino-acid racemase activity IEP Enrichment
CC GO:0048500 signal recognition particle IEP Enrichment
BP GO:0051276 chromosome organization IEP Enrichment
BP GO:0051641 cellular localization IEP Enrichment
BP GO:0051649 establishment of localization in cell IEP Enrichment
BP GO:0051668 localization within membrane IEP Enrichment
BP GO:0070727 cellular macromolecule localization IEP Enrichment
BP GO:0070972 protein localization to endoplasmic reticulum IEP Enrichment
BP GO:0071103 DNA conformation change IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0071840 cellular component organization or biogenesis IEP Enrichment
BP GO:0072594 establishment of protein localization to organelle IEP Enrichment
BP GO:0072599 establishment of protein localization to endoplasmic reticulum IEP Enrichment
BP GO:0072657 protein localization to membrane IEP Enrichment
BP GO:0090150 establishment of protein localization to membrane IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
CC GO:1990904 ribonucleoprotein complex IEP Enrichment
InterPro domains Description Start Stop
IPR004101 Mur_ligase_C 312 361
IPR000713 Mur_ligase_N 2 101
IPR013221 Mur_ligase_cen 108 291
UniProtKB P37773