AKI49129 (cobA, L2625_01218)

Aliases : cobA, L2625_01218

Description : uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase [Ensembl]. Tetrapyrrole methylase, Tetrapyrrole biosynthesis [Interproscan].

Gene families : OG_02_0000411 (OrthoFinder) Phylogenetic Tree(s): OG0000411_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49129
Cluster	HCCA: Cluster_9

Target	Alias	Description	ECC score	Gene Family Method
AAL20933	STM2029, cbiF	synthesis of vitamin B12 adenosyl cobalamide precursor...	0.32	OrthoFinder
AGT22826	N559_1047	hypothetical protein [Ensembl]. Tetrapyrrole...	0.14	OrthoFinder
CCL19868	cobA + hemD,...	Bifunctional uroporphyrinogen-III...	0.1	OrthoFinder
CCL19874	cbiF, BN171_3580009	Cobalt-precorrin-4 C(11)-methyltransferase...	0.06	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016835	carbon-oxygen lyase activity	None	Extended
MF	GO:0016836	hydro-lyase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	IEA	Interproscan
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	IEP	Enrichment
MF	GO:0005275	amine transmembrane transporter activity	IEP	Enrichment
BP	GO:0006766	vitamin metabolic process	IEP	Enrichment
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Enrichment
BP	GO:0006824	cobalt ion transport	IEP	Enrichment
MF	GO:0008818	cobalamin 5'-phosphate synthase activity	IEP	Enrichment
MF	GO:0008851	ethanolamine ammonia-lyase activity	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
BP	GO:0009235	cobalamin metabolic process	IEP	Enrichment
BP	GO:0009236	cobalamin biosynthetic process	IEP	Enrichment
MF	GO:0015087	cobalt ion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015101	organic cation transmembrane transporter activity	IEP	Enrichment
MF	GO:0015665	alcohol transmembrane transporter activity	IEP	Enrichment
BP	GO:0015695	organic cation transport	IEP	Enrichment
BP	GO:0015837	amine transport	IEP	Enrichment
BP	GO:0015850	organic hydroxy compound transport	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016840	carbon-nitrogen lyase activity	IEP	Enrichment
MF	GO:0016841	ammonia-lyase activity	IEP	Enrichment
MF	GO:0016852	sirohydrochlorin cobaltochelatase activity	IEP	Enrichment
MF	GO:0016867	intramolecular transferase activity, transferring acyl groups	IEP	Enrichment
MF	GO:0016993	precorrin-8X methylmutase activity	IEP	Enrichment
MF	GO:0016994	precorrin-6A reductase activity	IEP	Enrichment
BP	GO:0019251	anaerobic cobalamin biosynthetic process	IEP	Enrichment
MF	GO:0031419	cobalamin binding	IEP	Enrichment
MF	GO:0034228	ethanolamine transmembrane transporter activity	IEP	Enrichment
BP	GO:0034229	ethanolamine transport	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
MF	GO:0043752	adenosylcobinamide kinase activity	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
MF	GO:0048472	threonine-phosphate decarboxylase activity	IEP	Enrichment
MF	GO:0051073	adenosylcobinamide-GDP ribazoletransferase activity	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
MF	GO:1901618	organic hydroxy compound transmembrane transporter activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR000878	4pyrrol_Mease	3	213
IPR003754	4pyrrol_synth_uPrphyn_synth	265	481

External Links

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AKI49129 (cobA, L2625_01218)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation