AKI49282 (parE, L2625_01376)

Aliases : parE, L2625_01376

Description : DNA topoisomerase IV, B subunit [Ensembl]. DNA topoisomerase, TOPRIM domain, DNA gyrase B subunit, Histidine kinase/HSP90-like ATPase [Interproscan].

Gene families : OG_02_0000123 (OrthoFinder) Phylogenetic Tree(s): OG0000123_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49282
Cluster	HCCA: Cluster_18

Target	Alias	Description	ECC score	Gene Family Method
AAK99519	spr0715, gyrB	DNA gyrase [Ensembl]. Toprim domain, Histidine kinase-,...	0.05	OrthoFinder
AAL22055	STM3181, parE	DNA topoisomerase IV, subunit B [Ensembl]. Toprim...	0.04	OrthoFinder
AAL22694	STM3835, gyrB	DNA gyrase, subunit B [Ensembl]. Toprim domain,...	0.09	OrthoFinder
ADK86799	parE, MPNE_0140	DNA topoisomerase IV, B subunit [Ensembl]. DNA gyrase B,...	0.04	OrthoFinder
AGT21871	N559_0038	DNA gyrase subunit B [Ensembl]. DNA gyrase B subunit...	0.09	OrthoFinder
AGT22529	N559_0736	DNA topoisomerase IV subunit B [Ensembl]. Toprim domain,...	0.04	OrthoFinder
AHY39280	gyrB, CJ8421_00015	DNA gyrase subunit B [Ensembl]. Toprim domain, Histidine...	0.05	OrthoFinder
AKP15193	gyrB, WX61_01144	DNA gyrase subunit B [Ensembl]. Toprim domain, Histidine...	0.06	OrthoFinder
CBI66243	gyrB, HPB8_686	DNA gyrase, B subunit [Ensembl]. Toprim domain,...	0.03	OrthoFinder
CCL16917	gyrB, BN171_10005	DNA gyrase subunit B [Ensembl]. DNA gyrase B, Toprim...	0.13	OrthoFinder
CPC32854	parE, ERS093114_00063	Topoisomerase IV subunit B [Ensembl]. Toprim domain,...	0.07	OrthoFinder
CRO55054	parE	DNA topoisomerase 4 subunit B [Ensembl]. Toprim domain,...	0.06	OrthoFinder
CRP69988	gyrB	DNA gyrase subunit B [Ensembl]. Toprim domain, Histidine...	0.06	OrthoFinder
EDJ89973	CGSHi22421_07703	DNA topoisomerase IV subunit B [Ensembl]. Toprim domain,...	0.04	OrthoFinder
EDJ90160	gyrB, CGSHi22421_06007	DNA gyrase subunit B [Ensembl]. DNA gyrase B, Histidine...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	ATPase, acting on DNA	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
BP	GO:0001522	pseudouridine synthesis	IEP	Enrichment
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003735	structural constituent of ribosome	IEP	Enrichment
MF	GO:0003883	CTP synthase activity	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004017	adenylate kinase activity	IEP	Enrichment
MF	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Enrichment
MF	GO:0004652	polynucleotide adenylyltransferase activity	IEP	Enrichment
MF	GO:0004788	thiamine diphosphokinase activity	IEP	Enrichment
MF	GO:0004810	tRNA adenylyltransferase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005198	structural molecule activity	IEP	Enrichment
MF	GO:0005515	protein binding	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005840	ribosome	IEP	Enrichment
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006353	DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006412	translation	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006518	peptide metabolic process	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006528	asparagine metabolic process	IEP	Enrichment
BP	GO:0006529	asparagine biosynthetic process	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
MF	GO:0008135	translation factor activity, RNA binding	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
BP	GO:0008616	queuosine biosynthetic process	IEP	Enrichment
MF	GO:0008716	D-alanine-D-alanine ligase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009119	ribonucleoside metabolic process	IEP	Enrichment
BP	GO:0009163	nucleoside biosynthetic process	IEP	Enrichment
BP	GO:0009229	thiamine diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016758	hexosyltransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0030258	lipid modification	IEP	Enrichment
BP	GO:0030259	lipid glycosylation	IEP	Enrichment
MF	GO:0030975	thiamine binding	IEP	Enrichment
BP	GO:0031554	regulation of DNA-templated transcription, termination	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
BP	GO:0042357	thiamine diphosphate metabolic process	IEP	Enrichment
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043043	peptide biosynthetic process	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043228	non-membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Enrichment
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043412	macromolecule modification	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0043603	cellular amide metabolic process	IEP	Enrichment
BP	GO:0043604	amide biosynthetic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044267	cellular protein metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
MF	GO:0045182	translation regulator activity	IEP	Enrichment
BP	GO:0046116	queuosine metabolic process	IEP	Enrichment
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Enrichment
MF	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
BP	GO:0051304	chromosome separation	IEP	Enrichment
BP	GO:0052646	alditol phosphate metabolic process	IEP	Enrichment
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Enrichment
BP	GO:0070085	glycosylation	IEP	Enrichment
MF	GO:0070402	NADPH binding	IEP	Enrichment
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Enrichment
MF	GO:1990817	RNA adenylyltransferase activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR013506	Topo_IIA_bsu_dom2	221	391
IPR006171	TOPRIM_domain	422	522
IPR002288	DNA_gyrase_B_C	567	628
IPR003594	HATPase_C	31	174

External Links

No external refs found!

AKI49282 (parE, L2625_01376)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation