Coexpression cluster: Cluster_18 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0043170 macromolecule metabolic process 29.55% (39/132) 2.04 0.0 0.0
GO:0004812 aminoacyl-tRNA ligase activity 9.85% (13/132) 3.79 0.0 0.0
GO:0016875 ligase activity, forming carbon-oxygen bonds 9.85% (13/132) 3.79 0.0 0.0
GO:0043038 amino acid activation 9.85% (13/132) 3.79 0.0 0.0
GO:0043039 tRNA aminoacylation 9.85% (13/132) 3.79 0.0 0.0
GO:0006418 tRNA aminoacylation for protein translation 9.85% (13/132) 3.87 0.0 0.0
GO:0044237 cellular metabolic process 37.12% (49/132) 1.56 0.0 0.0
GO:0016070 RNA metabolic process 15.15% (20/132) 2.76 0.0 0.0
GO:0140098 catalytic activity, acting on RNA 12.88% (17/132) 3.04 0.0 0.0
GO:0006399 tRNA metabolic process 10.61% (14/132) 3.42 0.0 0.0
GO:0140101 catalytic activity, acting on a tRNA 10.61% (14/132) 3.42 0.0 0.0
GO:1901363 heterocyclic compound binding 40.15% (53/132) 1.35 0.0 0.0
GO:0097159 organic cyclic compound binding 40.15% (53/132) 1.35 0.0 0.0
GO:0016874 ligase activity 12.88% (17/132) 2.98 0.0 0.0
GO:0034641 cellular nitrogen compound metabolic process 28.03% (37/132) 1.75 0.0 0.0
GO:0009987 cellular process 45.45% (60/132) 1.17 0.0 0.0
GO:0006807 nitrogen compound metabolic process 32.58% (43/132) 1.49 0.0 0.0
GO:0008152 metabolic process 42.42% (56/132) 1.2 0.0 0.0
GO:0090304 nucleic acid metabolic process 17.42% (23/132) 2.27 0.0 0.0
GO:0005488 binding 43.18% (57/132) 1.16 0.0 0.0
GO:0003723 RNA binding 12.88% (17/132) 2.75 0.0 0.0
GO:0034660 ncRNA metabolic process 10.61% (14/132) 3.09 0.0 0.0
GO:0006139 nucleobase-containing compound metabolic process 21.21% (28/132) 1.95 0.0 0.0
GO:0044238 primary metabolic process 34.85% (46/132) 1.35 0.0 0.0
GO:0035639 purine ribonucleoside triphosphate binding 24.24% (32/132) 1.72 0.0 0.0
GO:0032555 purine ribonucleotide binding 24.24% (32/132) 1.72 0.0 0.0
GO:0017076 purine nucleotide binding 24.24% (32/132) 1.71 0.0 0.0
GO:0032553 ribonucleotide binding 24.24% (32/132) 1.66 0.0 0.0
GO:0097367 carbohydrate derivative binding 25.0% (33/132) 1.62 0.0 0.0
GO:0071704 organic substance metabolic process 37.88% (50/132) 1.19 0.0 0.0
GO:0006725 cellular aromatic compound metabolic process 21.97% (29/132) 1.73 0.0 0.0
GO:1901265 nucleoside phosphate binding 25.0% (33/132) 1.57 0.0 0.0
GO:0000166 nucleotide binding 25.0% (33/132) 1.57 0.0 0.0
GO:0003676 nucleic acid binding 23.48% (31/132) 1.62 0.0 0.0
GO:0003674 molecular_function 69.7% (92/132) 0.63 0.0 0.0
GO:1901360 organic cyclic compound metabolic process 21.97% (29/132) 1.67 0.0 0.0
GO:0046483 heterocycle metabolic process 21.21% (28/132) 1.65 0.0 0.0
GO:0006520 cellular amino acid metabolic process 11.36% (15/132) 2.46 0.0 0.0
GO:1901564 organonitrogen compound metabolic process 23.48% (31/132) 1.51 0.0 0.0
GO:0043168 anion binding 24.24% (32/132) 1.45 0.0 1e-06
GO:0008150 biological_process 56.82% (75/132) 0.72 0.0 1e-06
GO:0019752 carboxylic acid metabolic process 12.12% (16/132) 2.25 0.0 1e-06
GO:0043436 oxoacid metabolic process 12.12% (16/132) 2.25 0.0 1e-06
GO:0036094 small molecule binding 25.0% (33/132) 1.37 0.0 1e-06
GO:0006082 organic acid metabolic process 12.12% (16/132) 2.17 0.0 2e-06
GO:0043167 ion binding 25.76% (34/132) 1.28 0.0 3e-06
GO:0034645 cellular macromolecule biosynthetic process 10.61% (14/132) 2.22 1e-06 7e-06
GO:0044260 cellular macromolecule metabolic process 13.64% (18/132) 1.82 2e-06 1.5e-05
GO:0005524 ATP binding 18.18% (24/132) 1.48 2e-06 1.8e-05
GO:0032559 adenyl ribonucleotide binding 18.18% (24/132) 1.48 2e-06 1.8e-05
GO:0030554 adenyl nucleotide binding 18.18% (24/132) 1.48 2e-06 1.9e-05
GO:0044281 small molecule metabolic process 16.67% (22/132) 1.56 2e-06 2e-05
GO:0009059 macromolecule biosynthetic process 10.61% (14/132) 2.07 3e-06 2.4e-05
GO:0005525 GTP binding 6.06% (8/132) 2.77 1e-05 7.8e-05
GO:0019001 guanyl nucleotide binding 6.06% (8/132) 2.77 1e-05 7.8e-05
GO:0032561 guanyl ribonucleotide binding 6.06% (8/132) 2.77 1e-05 7.8e-05
GO:1901576 organic substance biosynthetic process 16.67% (22/132) 1.37 2.3e-05 0.000167
GO:0003924 GTPase activity 3.79% (5/132) 3.57 2.3e-05 0.000168
GO:0016462 pyrophosphatase activity 4.55% (6/132) 3.09 3.3e-05 0.000238
GO:0044249 cellular biosynthetic process 15.91% (21/132) 1.33 5.3e-05 0.000369
GO:0009058 biosynthetic process 17.42% (23/132) 1.25 5.8e-05 0.000403
GO:0090079 translation regulator activity, nucleic acid binding 3.03% (4/132) 3.83 6.4e-05 0.000423
GO:0045182 translation regulator activity 3.03% (4/132) 3.83 6.4e-05 0.000423
GO:0008135 translation factor activity, RNA binding 3.03% (4/132) 3.83 6.4e-05 0.000423
GO:0017111 nucleoside-triphosphatase activity 3.79% (5/132) 3.28 7.7e-05 0.000484
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.55% (6/132) 2.91 7.6e-05 0.000487
GO:0016817 hydrolase activity, acting on acid anhydrides 4.55% (6/132) 2.91 7.6e-05 0.000487
GO:0019538 protein metabolic process 9.85% (13/132) 1.76 8.1e-05 0.000501
GO:0005840 ribosome 6.82% (9/132) 2.19 9.9e-05 0.000604
GO:0042886 amide transport 2.27% (3/132) 4.42 0.000101 0.000605
GO:0044267 cellular protein metabolic process 7.58% (10/132) 2.04 0.000107 0.000632
GO:0006412 translation 6.82% (9/132) 2.13 0.000145 0.000849
GO:0003824 catalytic activity 40.15% (53/132) 0.64 0.000161 0.000929
GO:0003735 structural constituent of ribosome 6.82% (9/132) 2.09 0.000174 0.000966
GO:0043229 intracellular organelle 6.82% (9/132) 2.09 0.000174 0.000966
GO:0043232 intracellular non-membrane-bounded organelle 6.82% (9/132) 2.09 0.000174 0.000966
GO:0043043 peptide biosynthetic process 6.82% (9/132) 2.06 0.000208 0.001125
GO:0006518 peptide metabolic process 6.82% (9/132) 2.06 0.000208 0.001125
GO:0043228 non-membrane-bounded organelle 6.82% (9/132) 2.03 0.000248 0.001303
GO:0043226 organelle 6.82% (9/132) 2.03 0.000248 0.001303
GO:0043604 amide biosynthetic process 6.82% (9/132) 2.0 0.000293 0.001504
GO:0043603 cellular amide metabolic process 6.82% (9/132) 2.0 0.000293 0.001504
GO:0044271 cellular nitrogen compound biosynthetic process 11.36% (15/132) 1.44 0.000301 0.001525
GO:0005198 structural molecule activity 6.82% (9/132) 1.97 0.000345 0.001728
GO:0002161 aminoacyl-tRNA editing activity 2.27% (3/132) 4.0 0.000389 0.001926
GO:0052689 carboxylic ester hydrolase activity 2.27% (3/132) 3.68 0.000939 0.004391
GO:0000049 tRNA binding 2.27% (3/132) 3.68 0.000939 0.004391
GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2.27% (3/132) 3.68 0.000939 0.004391
GO:0034062 5'-3' RNA polymerase activity 2.27% (3/132) 3.68 0.000939 0.004391
GO:0097747 RNA polymerase activity 2.27% (3/132) 3.68 0.000939 0.004391
GO:0043412 macromolecule modification 3.79% (5/132) 2.49 0.001431 0.006622
GO:0006413 translational initiation 1.52% (2/132) 4.42 0.00218 0.009086
GO:0032259 methylation 1.52% (2/132) 4.42 0.00218 0.009086
GO:0006426 glycyl-tRNA aminoacylation 1.52% (2/132) 4.42 0.00218 0.009086
GO:0090482 vitamin transmembrane transporter activity 1.52% (2/132) 4.42 0.00218 0.009086
GO:0015833 peptide transport 1.52% (2/132) 4.42 0.00218 0.009086
GO:0004820 glycine-tRNA ligase activity 1.52% (2/132) 4.42 0.00218 0.009086
GO:0003743 translation initiation factor activity 1.52% (2/132) 4.42 0.00218 0.009086
GO:0051180 vitamin transport 1.52% (2/132) 4.42 0.00218 0.009086
GO:0006432 phenylalanyl-tRNA aminoacylation 1.52% (2/132) 4.42 0.00218 0.009086
GO:0004826 phenylalanine-tRNA ligase activity 1.52% (2/132) 4.42 0.00218 0.009086
GO:0016879 ligase activity, forming carbon-nitrogen bonds 3.03% (4/132) 2.72 0.002368 0.009772
GO:0005737 cytoplasm 3.79% (5/132) 2.28 0.002894 0.011829
GO:0005575 cellular_component 21.21% (28/132) 0.71 0.004575 0.018519
GO:1901566 organonitrogen compound biosynthetic process 9.85% (13/132) 1.1 0.006397 0.025406
GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1.52% (2/132) 3.83 0.006338 0.025413
GO:0016779 nucleotidyltransferase activity 3.03% (4/132) 2.33 0.006809 0.026791
GO:0110165 cellular anatomical entity 19.7% (26/132) 0.69 0.008078 0.031491
GO:0034654 nucleobase-containing compound biosynthetic process 4.55% (6/132) 1.72 0.008602 0.033224
GO:0009451 RNA modification 2.27% (3/132) 2.68 0.009471 0.036249
GO:0005886 plasma membrane 1.52% (2/132) 3.42 0.012288 0.045378
GO:1901682 sulfur compound transmembrane transporter activity 1.52% (2/132) 3.42 0.012288 0.045378
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity 1.52% (2/132) 3.42 0.012288 0.045378
GO:0072348 sulfur compound transport 1.52% (2/132) 3.42 0.012288 0.045378
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_1 0.04 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_2 0.045 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_8 0.054 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_2 0.076 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_15 0.028 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_19 0.043 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_27 0.031 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_30 0.048 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_35 0.033 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_2 0.035 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_7 0.058 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_12 0.106 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_13 0.041 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_19 0.035 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_21 0.067 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_28 0.048 OrthoFinder Compare
Escherichia coli HCCA Cluster_1 0.083 OrthoFinder Compare
Escherichia coli HCCA Cluster_29 0.054 OrthoFinder Compare
Escherichia coli HCCA Cluster_37 0.053 OrthoFinder Compare
Escherichia coli HCCA Cluster_40 0.028 OrthoFinder Compare
Escherichia coli HCCA Cluster_41 0.05 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_7 0.056 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_8 0.041 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_9 0.029 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_11 0.066 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_12 0.036 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_15 0.038 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_8 0.033 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_9 0.04 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_14 0.042 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_16 0.036 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_12 0.06 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_26 0.069 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_44 0.08 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_1 0.042 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_3 0.047 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_1 0.035 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_6 0.031 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_7 0.042 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_8 0.031 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.086 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_22 0.036 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_22 0.04 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_34 0.043 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_35 0.029 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_39 0.034 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_51 0.077 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_62 0.028 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_63 0.037 OrthoFinder Compare
Salmonella enterica HCCA Cluster_3 0.054 OrthoFinder Compare
Salmonella enterica HCCA Cluster_5 0.03 OrthoFinder Compare
Salmonella enterica HCCA Cluster_7 0.031 OrthoFinder Compare
Salmonella enterica HCCA Cluster_23 0.059 OrthoFinder Compare
Salmonella enterica HCCA Cluster_31 0.055 OrthoFinder Compare
Salmonella enterica HCCA Cluster_39 0.031 OrthoFinder Compare
Salmonella enterica HCCA Cluster_42 0.032 OrthoFinder Compare
Salmonella enterica HCCA Cluster_45 0.028 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_1 0.03 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_5 0.077 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_14 0.028 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_19 0.068 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_24 0.048 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_2 0.033 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_3 0.027 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_4 0.028 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_13 0.072 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.058 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_16 0.031 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_18 0.063 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_19 0.028 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_4 0.092 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_7 0.044 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_10 0.031 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_11 0.089 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_18 0.028 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_1 0.038 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_8 0.043 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_24 0.097 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_32 0.036 OrthoFinder Compare
Sequences (132) (download table)

InterPro Domains

GO Terms

Family Terms