AKI50033 (murE, L2625_02188)

Aliases : murE, L2625_02188

Description : UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase [Ensembl]. Mur ligase [Interproscan].

Gene families : OG_02_0000864 (OrthoFinder) Phylogenetic Tree(s): OG0000864_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI50033
Cluster	HCCA: Cluster_24

Target	Alias	Description	ECC score	Gene Family Method
AAC73196	murE, b0085	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-diaminopim...	0.06	OrthoFinder
AAL00188	spr1384, murE	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine Ligase...	0.04	OrthoFinder
AAL19087	STM0123, murE	UDP-N-acetylmuramoylalanyl-D-glutamate...	0.05	OrthoFinder
CCG27522	No alias	UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase...	0.04	OrthoFinder
KNA53282	VCV51_033343	UDP-N-acetylmuramyl-tripeptide synthetase [Ensembl]. Mur...	0.06	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	IEA	Interproscan
MF	GO:0016874	ligase activity	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
BP	GO:0000902	cell morphogenesis	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0004478	methionine adenosyltransferase activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0004527	exonuclease activity	IEP	Enrichment
MF	GO:0004788	thiamine diphosphokinase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006298	mismatch repair	IEP	Enrichment
BP	GO:0006353	DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006400	tRNA modification	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006556	S-adenosylmethionine biosynthetic process	IEP	Enrichment
BP	GO:0006605	protein targeting	IEP	Enrichment
BP	GO:0006612	protein targeting to membrane	IEP	Enrichment
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006886	intracellular protein transport	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
BP	GO:0008033	tRNA processing	IEP	Enrichment
MF	GO:0008144	drug binding	IEP	Enrichment
MF	GO:0008168	methyltransferase activity	IEP	Enrichment
MF	GO:0008173	RNA methyltransferase activity	IEP	Enrichment
MF	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
MF	GO:0008408	3'-5' exonuclease activity	IEP	Enrichment
MF	GO:0008531	riboflavin kinase activity	IEP	Enrichment
MF	GO:0008658	penicillin binding	IEP	Enrichment
BP	GO:0009229	thiamine diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
BP	GO:0009653	anatomical structure morphogenesis	IEP	Enrichment
BP	GO:0009987	cellular process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Enrichment
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Enrichment
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0030975	thiamine binding	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
MF	GO:0031406	carboxylic acid binding	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0033293	monocarboxylic acid binding	IEP	Enrichment
BP	GO:0033365	protein localization to organelle	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
BP	GO:0034613	cellular protein localization	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
BP	GO:0042357	thiamine diphosphate metabolic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
MF	GO:0043177	organic acid binding	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044237	cellular metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Enrichment
BP	GO:0045047	protein targeting to ER	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046500	S-adenosylmethionine metabolic process	IEP	Enrichment
BP	GO:0046907	intracellular transport	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
BP	GO:0051641	cellular localization	IEP	Enrichment
BP	GO:0051649	establishment of localization in cell	IEP	Enrichment
BP	GO:0051668	localization within membrane	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
MF	GO:0070402	NADPH binding	IEP	Enrichment
BP	GO:0070727	cellular macromolecule localization	IEP	Enrichment
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0071704	organic substance metabolic process	IEP	Enrichment
BP	GO:0071705	nitrogen compound transport	IEP	Enrichment
BP	GO:0072594	establishment of protein localization to organelle	IEP	Enrichment
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072657	protein localization to membrane	IEP	Enrichment
BP	GO:0090150	establishment of protein localization to membrane	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
MF	GO:1901681	sulfur compound binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004101	Mur_ligase_C	332	417
IPR000713	Mur_ligase_N	22	94
IPR013221	Mur_ligase_cen	106	311

External Links

No external refs found!

AKI50033 (murE, L2625_02188)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation