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  5. AKP14226

AKP14226 (lpdA, WX61_00137)


Aliases : lpdA, WX61_00137

Description : Dihydrolipoyl dehydrogenase [Ensembl]. Biotin-requiring enzyme, Pyridine nucleotide-disulphide oxidoreductase [Interproscan].


Gene families : OG_02_0000040 (OrthoFinder) Phylogenetic Tree(s): OG0000040_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AKP14226
Cluster HCCA: Cluster_12

Target Alias Description ECC score Gene Family Method Actions
AAC73227 lpd, b0116 dihydrolipoyl dehydrogenase; E3 component of pyruvate... 0.06 OrthoFinder
AAC76525 gor, b3500 glutathione oxidoreductase [Ensembl]. Pyridine... 0.04 OrthoFinder
AAK99496 spr0692, gor Glutathione oxidoreductase [Ensembl]. Pyridine... 0.04 OrthoFinder
AAK99852 spr1048, acoL Dihydrolipoamide dehydrogenase [Ensembl].... 0.07 OrthoFinder
AAL00246 spr1442, merA Oxidoreductase (Mercury (II) reductase) [Ensembl].... 0.04 OrthoFinder
AAL19118 STM0154, lpdA lipoamide dehydrogenase (NADH) [Ensembl]. Pyridine... 0.05 OrthoFinder
AAL22457 STM3597, gor glutathione oxidoreductase [Ensembl]. Pyridine... 0.02 OrthoFinder
ADK87170 lpdA, MPNE_0452 dihydrolipoyl dehydrogenase [Ensembl]. Pyridine... 0.04 OrthoFinder
AGT25777 N559_4152 dihydrolipoamide dehydrogenase [Ensembl]. dimerisation... 0.02 OrthoFinder
AGT25922 N559_4307 dihydrolipoamide dehydrogenase [Ensembl]. dimerisation... 0.06 OrthoFinder
CCG26577 No alias Glutathione reductase [Ensembl]. Pyridine... 0.03 OrthoFinder
CCG27407 No alias Dihydrolipoamide dehydrogenase of acetoin dehydrogenase... 0.03 OrthoFinder
CPC40095 pdhD, ERS093114_00328 Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase... 0.07 OrthoFinder
CPC80109 ERS093114_01350 Dihydrolipoamide dehydrogenase of branched-chain... 0.06 OrthoFinder
CRO91700 sthA Soluble pyridine nucleotide transhydrogenase [Ensembl].... 0.02 OrthoFinder
CRO96265 garB Glutathione amide reductase [Ensembl]. Pyridine... 0.02 OrthoFinder
CRP29375 lpd Dihydrolipoyl dehydrogenase [Ensembl]. Pyridine... 0.03 OrthoFinder
EDJ90985 CGSHi22421_02646 dihydrolipoamide dehydrogenase [Ensembl]. Pyridine... 0.04 OrthoFinder
KNA53278 VCV51_031622 dihydrolipoyl dehydrogenase [Ensembl]. Pyridine... 0.1 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0016491 oxidoreductase activity IEA Interproscan
BP GO:0045454 cell redox homeostasis IEA Interproscan
BP GO:0055114 obsolete oxidation-reduction process IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0002161 aminoacyl-tRNA editing activity IEP Enrichment
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Enrichment
MF GO:0003911 DNA ligase (NAD+) activity IEP Enrichment
MF GO:0003916 DNA topoisomerase activity IEP Enrichment
MF GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEP Enrichment
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Enrichment
MF GO:0003924 GTPase activity IEP Enrichment
MF GO:0004176 ATP-dependent peptidase activity IEP Enrichment
MF GO:0004325 ferrochelatase activity IEP Enrichment
MF GO:0004363 glutathione synthase activity IEP Enrichment
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004817 cysteine-tRNA ligase activity IEP Enrichment
MF GO:0004832 valine-tRNA ligase activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
CC GO:0005737 cytoplasm IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006098 pentose-phosphate shunt IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006177 GMP biosynthetic process IEP Enrichment
BP GO:0006265 DNA topological change IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006423 cysteinyl-tRNA aminoacylation IEP Enrichment
BP GO:0006438 valyl-tRNA aminoacylation IEP Enrichment
BP GO:0006518 peptide metabolic process IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006740 NADPH regeneration IEP Enrichment
BP GO:0006749 glutathione metabolic process IEP Enrichment
BP GO:0006750 glutathione biosynthetic process IEP Enrichment
BP GO:0006783 heme biosynthetic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006996 organelle organization IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
BP GO:0009058 biosynthetic process IEP Enrichment
BP GO:0009059 macromolecule biosynthetic process IEP Enrichment
BP GO:0009086 methionine biosynthetic process IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
BP GO:0016310 phosphorylation IEP Enrichment
MF GO:0016462 pyrophosphatase activity IEP Enrichment
MF GO:0016787 hydrolase activity IEP Enrichment
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Enrichment
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0017111 nucleoside-triphosphatase activity IEP Enrichment
MF GO:0019001 guanyl nucleotide binding IEP Enrichment
BP GO:0019184 nonribosomal peptide biosynthetic process IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
BP GO:0031554 regulation of DNA-templated transcription, termination IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
MF GO:0032561 guanyl ribonucleotide binding IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034645 cellular macromolecule biosynthetic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
BP GO:0043043 peptide biosynthetic process IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0043170 macromolecule metabolic process IEP Enrichment
BP GO:0043244 regulation of protein-containing complex disassembly IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
BP GO:0043603 cellular amide metabolic process IEP Enrichment
BP GO:0043604 amide biosynthetic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Enrichment
BP GO:0044272 sulfur compound biosynthetic process IEP Enrichment
BP GO:0044281 small molecule metabolic process IEP Enrichment
BP GO:0046037 GMP metabolic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
BP GO:0051276 chromosome organization IEP Enrichment
MF GO:0052689 carboxylic ester hydrolase activity IEP Enrichment
BP GO:0071103 DNA conformation change IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
BP GO:1901566 organonitrogen compound biosynthetic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR000089 Biotin_lipoyl 5 75
IPR004099 Pyr_nucl-diS_OxRdtase_dimer 469 577
IPR023753 FAD/NAD-binding_dom 118 450
No external refs found!