AKP15249 (polA, WX61_01200)

Aliases : polA, WX61_01200

Description : DNA polymerase I [Ensembl]. 5'-3' exonuclease, 3'-5' exonuclease, DNA polymerase family A [Interproscan].

Gene families : OG_02_0000357 (OrthoFinder) Phylogenetic Tree(s): OG0000357_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKP15249
Cluster	HCCA: Cluster_12

Target	Alias	Description	ECC score	Gene Family Method
AAL22838	STM3999, polA	DNA polymerase I [Ensembl]. 5'-3' exonuclease, 3'-5'...	0.04	OrthoFinder
CCG26484	No alias	DNA polymerase I [Ensembl]. 5'-3' exonuclease, DNA...	0.02	OrthoFinder
CPC75542	ypcP, ERS093114_01206	DNA polymerase I [Ensembl]. 5'-3' exonuclease [Interproscan].	0.03	OrthoFinder
CRP72964	polA	DNA polymerase I [Ensembl]. 3'-5' exonuclease, 5'-3'...	0.03	OrthoFinder
EDJ91438	CGSHi22421_05023	DNA polymerase I [Ensembl]. 3'-5' exonuclease, DNA...	0.05	OrthoFinder
EDJ91632	CGSHi22421_07753	DNA polymerase I [Ensembl]. 5'-3' exonuclease [Interproscan].	0.07	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	IEA	Interproscan
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004527	exonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	IEA	Interproscan
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008408	3'-5' exonuclease activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003852	2-isopropylmalate synthase activity	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0004127	cytidylate kinase activity	IEP	Enrichment
MF	GO:0004356	glutamate-ammonia ligase activity	IEP	Enrichment
MF	GO:0004358	glutamate N-acetyltransferase activity	IEP	Enrichment
MF	GO:0004375	glycine dehydrogenase (decarboxylating) activity	IEP	Enrichment
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEP	Enrichment
MF	GO:0004743	pyruvate kinase activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005694	chromosome	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006284	base-excision repair	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006541	glutamine metabolic process	IEP	Enrichment
BP	GO:0006542	glutamine biosynthetic process	IEP	Enrichment
BP	GO:0006544	glycine metabolic process	IEP	Enrichment
BP	GO:0006546	glycine catabolic process	IEP	Enrichment
BP	GO:0006551	leucine metabolic process	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
MF	GO:0008080	N-acetyltransferase activity	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Enrichment
MF	GO:0008703	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	IEP	Enrichment
MF	GO:0008915	lipid-A-disaccharide synthase activity	IEP	Enrichment
MF	GO:0008964	phosphoenolpyruvate carboxylase activity	IEP	Enrichment
BP	GO:0009056	catabolic process	IEP	Enrichment
BP	GO:0009063	cellular amino acid catabolic process	IEP	Enrichment
BP	GO:0009064	glutamine family amino acid metabolic process	IEP	Enrichment
BP	GO:0009071	serine family amino acid catabolic process	IEP	Enrichment
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009098	leucine biosynthetic process	IEP	Enrichment
BP	GO:0015977	carbon fixation	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016054	organic acid catabolic process	IEP	Enrichment
MF	GO:0016211	ammonia ligase activity	IEP	Enrichment
MF	GO:0016407	acetyltransferase activity	IEP	Enrichment
MF	GO:0016410	N-acyltransferase activity	IEP	Enrichment
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Enrichment
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Enrichment
MF	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
MF	GO:0016744	transketolase or transaldolase activity	IEP	Enrichment
MF	GO:0016746	acyltransferase activity	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016831	carboxy-lyase activity	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016880	acid-ammonia (or amide) ligase activity	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0030955	potassium ion binding	IEP	Enrichment
MF	GO:0031420	alkali metal ion binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046395	carboxylic acid catabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Enrichment
BP	GO:1901575	organic substance catabolic process	IEP	Enrichment
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Enrichment
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Enrichment
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR020046	5-3_exonucl_a-hlix_arch_N	7	169
IPR001098	DNA-dir_DNA_pol_A_palm_dom	550	928
IPR020045	DNA_polI_H3TH	170	256
IPR002562	3'-5'_exonuclease_dom	332	517

External Links

No external refs found!

AKP15249 (polA, WX61_01200)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation