AAL22048 (STM3174, parC)

Aliases : STM3174, parC

Description : DNA topoisomerase IV, subunit A [Ensembl]. DNA gyrase/topoisomerase IV, DNA gyrase C-terminal domain [Interproscan].

Gene families : OG_02_0001962 (OrthoFinder) Phylogenetic Tree(s): OG0001962_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAL22048
Cluster	HCCA: Cluster_31

Target	Alias	Description	ECC score	Gene Family Method
AAC76055	parC, b3019	DNA topoisomerase IV, subunit A [Ensembl]. DNA...	0.19	OrthoFinder
AGT22536	N559_0743	DNA topoisomerase IV subunit A [Ensembl]. DNA gyrase...	0.1	OrthoFinder
CRO54978	parC	DNA topoisomerase 4 subunit A [Ensembl]. DNA...	0.06	OrthoFinder
EDJ89974	CGSHi22421_07708	DNA topoisomerase IV subunit A [Ensembl]. DNA...	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	ATPase, acting on DNA	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0003919	FMN adenylyltransferase activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005315	inorganic phosphate transmembrane transporter activity	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006364	rRNA processing	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006817	phosphate ion transport	IEP	Enrichment
MF	GO:0008144	drug binding	IEP	Enrichment
MF	GO:0008171	O-methyltransferase activity	IEP	Enrichment
MF	GO:0008173	RNA methyltransferase activity	IEP	Enrichment
MF	GO:0008175	tRNA methyltransferase activity	IEP	Enrichment
MF	GO:0008236	serine-type peptidase activity	IEP	Enrichment
BP	GO:0008360	regulation of cell shape	IEP	Enrichment
MF	GO:0008531	riboflavin kinase activity	IEP	Enrichment
MF	GO:0008658	penicillin binding	IEP	Enrichment
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Enrichment
MF	GO:0008990	rRNA (guanine-N2-)-methyltransferase activity	IEP	Enrichment
MF	GO:0009020	tRNA (guanosine-2'-O-)-methyltransferase activity	IEP	Enrichment
MF	GO:0009029	tetraacyldisaccharide 4'-kinase activity	IEP	Enrichment
BP	GO:0009143	nucleoside triphosphate catabolic process	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
BP	GO:0015969	guanosine tetraphosphate metabolic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
BP	GO:0016072	rRNA metabolic process	IEP	Enrichment
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Enrichment
MF	GO:0016435	rRNA (guanine) methyltransferase activity	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0017171	serine hydrolase activity	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0022603	regulation of anatomical structure morphogenesis	IEP	Enrichment
BP	GO:0022604	regulation of cell morphogenesis	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
MF	GO:0031406	carboxylic acid binding	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
MF	GO:0033218	amide binding	IEP	Enrichment
MF	GO:0033293	monocarboxylic acid binding	IEP	Enrichment
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	IEP	Enrichment
MF	GO:0034061	DNA polymerase activity	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043177	organic acid binding	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0050793	regulation of developmental process	IEP	Enrichment
MF	GO:0062105	RNA 2'-O-methyltransferase activity	IEP	Enrichment
MF	GO:0070567	cytidylyltransferase activity	IEP	Enrichment
MF	GO:0106050	tRNA 2'-O-methyltransferase activity	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
MF	GO:1901681	sulfur compound binding	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006691	GyrA/parC_rep	641	692
IPR006691	GyrA/parC_rep	593	630
IPR002205	Topo_IIA_A/C	29	465

External Links

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AAL22048 (STM3174, parC)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation