CCG26876

Description : Isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases class I (I, Anticodon-binding domain of tRNA [Interproscan].

Gene families : OG_02_0000544 (OrthoFinder) Phylogenetic Tree(s): OG0000544_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCG26876
Cluster	HCAA: Cluster_4

Target	Alias	Description	ECC score	Gene Family Method
AAL00306	spr1502, ileS	Isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.1	OrthoFinder
AEA93423	ileS, OG1RF_10736	isoleucine--tRNA ligase [Ensembl]. tRNA synthetases...	0.06	OrthoFinder
AGT26019	N559_4412	isoleucine--tRNA ligase [Ensembl]. Anticodon-binding...	0.03	OrthoFinder
AHY40269	ileS, CJ8421_05275	isoleucyl-tRNA ligase [Ensembl]. tRNA synthetases class...	0.04	OrthoFinder
AKI50014	ileS, L2625_02167	isoleucyl-tRNA synthetase [Ensembl]....	0.03	OrthoFinder
CBI65679	ileS, HPB8_122	isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.03	OrthoFinder
CRN65985	ileS	Isoleucine--tRNA ligase [Ensembl]. tRNA synthetases...	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Enrichment
MF	GO:0003909	DNA ligase activity	IEP	Enrichment
MF	GO:0003911	DNA ligase (NAD+) activity	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004601	peroxidase activity	IEP	Enrichment
MF	GO:0004602	glutathione peroxidase activity	IEP	Enrichment
MF	GO:0004618	phosphoglycerate kinase activity	IEP	Enrichment
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006351	transcription, DNA-templated	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006979	response to oxidative stress	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0016209	antioxidant activity	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016774	phosphotransferase activity, carboxyl group as acceptor	IEP	Enrichment
MF	GO:0016778	diphosphotransferase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
MF	GO:0046872	metal ion binding	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0097659	nucleic acid-templated transcription	IEP	Enrichment
MF	GO:0097747	RNA polymerase activity	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002300	aa-tRNA-synth_Ia	26	634
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	678	832

External Links

No external refs found!

CCG26876

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation