Coexpression cluster: Cluster_4 (HCAA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0005198 structural molecule activity 9.05% (19/210) 1.91 0.0 8e-06
GO:0003735 structural constituent of ribosome 9.05% (19/210) 1.91 0.0 8e-06
GO:0005840 ribosome 8.57% (18/210) 1.9 0.0 1.3e-05
GO:0043232 intracellular non-membrane-bounded organelle 8.57% (18/210) 1.79 0.0 2.1e-05
GO:0043228 non-membrane-bounded organelle 8.57% (18/210) 1.79 0.0 2.1e-05
GO:0043229 intracellular organelle 8.57% (18/210) 1.79 0.0 2.1e-05
GO:0043226 organelle 8.57% (18/210) 1.79 0.0 2.1e-05
GO:0005575 cellular_component 19.05% (40/210) 1.12 0.0 2.5e-05
GO:0110165 cellular anatomical entity 18.1% (38/210) 1.1 1e-06 3.7e-05
GO:0034641 cellular nitrogen compound metabolic process 12.38% (26/210) 1.34 2e-06 7.3e-05
GO:0006418 tRNA aminoacylation for protein translation 3.33% (7/210) 2.79 3e-06 0.000106
GO:0006139 nucleobase-containing compound metabolic process 10.95% (23/210) 1.36 7e-06 0.000208
GO:0046483 heterocycle metabolic process 10.95% (23/210) 1.3 1.6e-05 0.000365
GO:0006725 cellular aromatic compound metabolic process 10.95% (23/210) 1.3 1.6e-05 0.000365
GO:1901360 organic cyclic compound metabolic process 10.95% (23/210) 1.3 1.6e-05 0.000365
GO:0009141 nucleoside triphosphate metabolic process 2.38% (5/210) 2.98 3.1e-05 0.000668
GO:0043038 amino acid activation 3.33% (7/210) 2.47 4.1e-05 0.000775
GO:0043039 tRNA aminoacylation 3.33% (7/210) 2.47 4.1e-05 0.000775
GO:0044281 small molecule metabolic process 6.67% (14/210) 1.58 7.5e-05 0.001283
GO:0006807 nitrogen compound metabolic process 13.81% (29/210) 1.02 7.2e-05 0.001299
GO:0006399 tRNA metabolic process 3.81% (8/210) 2.17 8.8e-05 0.001317
GO:0044238 primary metabolic process 15.71% (33/210) 0.93 8.7e-05 0.001359
GO:0046034 ATP metabolic process 2.86% (6/210) 2.57 8.7e-05 0.001413
GO:0009201 ribonucleoside triphosphate biosynthetic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0009142 nucleoside triphosphate biosynthetic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0009205 purine ribonucleoside triphosphate metabolic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0009260 ribonucleotide biosynthetic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0015985 energy coupled proton transport, down electrochemical gradient 1.9% (4/210) 2.98 0.00025 0.002095
GO:0015986 ATP synthesis coupled proton transport 1.9% (4/210) 2.98 0.00025 0.002095
GO:0009199 ribonucleoside triphosphate metabolic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0046390 ribose phosphate biosynthetic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0009145 purine nucleoside triphosphate biosynthetic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0009144 purine nucleoside triphosphate metabolic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0006754 ATP biosynthetic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:0009152 purine ribonucleotide biosynthetic process 1.9% (4/210) 2.98 0.00025 0.002095
GO:1901564 organonitrogen compound metabolic process 8.57% (18/210) 1.22 0.000298 0.002432
GO:0071704 organic substance metabolic process 16.67% (35/210) 0.84 0.000187 0.002673
GO:0140098 catalytic activity, acting on RNA 5.24% (11/210) 1.69 0.000213 0.0027
GO:0016875 ligase activity, forming carbon-oxygen bonds 4.29% (9/210) 1.9 0.000208 0.002746
GO:0004812 aminoacyl-tRNA ligase activity 4.29% (9/210) 1.9 0.000208 0.002746
GO:0044237 cellular metabolic process 13.81% (29/210) 0.93 0.000232 0.002843
GO:0009150 purine ribonucleotide metabolic process 2.38% (5/210) 2.5 0.000526 0.003685
GO:0019693 ribose phosphate metabolic process 2.38% (5/210) 2.5 0.000526 0.003685
GO:0009259 ribonucleotide metabolic process 2.38% (5/210) 2.5 0.000526 0.003685
GO:0090304 nucleic acid metabolic process 8.1% (17/210) 1.21 0.000482 0.003844
GO:0140101 catalytic activity, acting on a tRNA 4.29% (9/210) 1.76 0.000526 0.003924
GO:0003674 molecular_function 39.52% (83/210) 0.42 0.000584 0.003928
GO:0034660 ncRNA metabolic process 3.81% (8/210) 1.89 0.000508 0.003957
GO:0006753 nucleoside phosphate metabolic process 2.86% (6/210) 2.24 0.000519 0.003959
GO:0043170 macromolecule metabolic process 11.43% (24/210) 0.97 0.00058 0.003981
GO:0016874 ligase activity 5.24% (11/210) 1.53 0.000628 0.004144
GO:0016070 RNA metabolic process 5.71% (12/210) 1.44 0.00072 0.004658
GO:0044271 cellular nitrogen compound biosynthetic process 4.29% (9/210) 1.69 0.000794 0.005043
GO:0006164 purine nucleotide biosynthetic process 1.9% (4/210) 2.66 0.001127 0.006553
GO:0009165 nucleotide biosynthetic process 1.9% (4/210) 2.66 0.001127 0.006553
GO:1901293 nucleoside phosphate biosynthetic process 1.9% (4/210) 2.66 0.001127 0.006553
GO:1901137 carbohydrate derivative biosynthetic process 1.9% (4/210) 2.66 0.001127 0.006553
GO:0072522 purine-containing compound biosynthetic process 1.9% (4/210) 2.66 0.001127 0.006553
GO:0072521 purine-containing compound metabolic process 2.38% (5/210) 2.3 0.00126 0.006968
GO:0006163 purine nucleotide metabolic process 2.38% (5/210) 2.3 0.00126 0.006968
GO:0019637 organophosphate metabolic process 3.33% (7/210) 1.88 0.001241 0.007094
GO:0097367 carbohydrate derivative binding 12.86% (27/210) 0.81 0.001702 0.009269
GO:0034654 nucleobase-containing compound biosynthetic process 2.86% (6/210) 1.98 0.001831 0.009664
GO:0055086 nucleobase-containing small molecule metabolic process 2.86% (6/210) 1.98 0.001831 0.009664
GO:0006520 cellular amino acid metabolic process 3.33% (7/210) 1.79 0.001972 0.010247
GO:0008152 metabolic process 17.14% (36/210) 0.66 0.002054 0.010513
GO:0035639 purine ribonucleoside triphosphate binding 12.38% (26/210) 0.8 0.002228 0.010918
GO:0017076 purine nucleotide binding 12.38% (26/210) 0.8 0.002228 0.010918
GO:0032555 purine ribonucleotide binding 12.38% (26/210) 0.8 0.002228 0.010918
GO:0090407 organophosphate biosynthetic process 2.38% (5/210) 2.13 0.002544 0.011953
GO:0009117 nucleotide metabolic process 2.38% (5/210) 2.13 0.002544 0.011953
GO:0043167 ion binding 14.29% (30/210) 0.72 0.002605 0.012073
GO:0019752 carboxylic acid metabolic process 3.81% (8/210) 1.59 0.002697 0.012171
GO:0043436 oxoacid metabolic process 3.81% (8/210) 1.59 0.002697 0.012171
GO:0032553 ribonucleotide binding 12.38% (26/210) 0.79 0.002533 0.012236
GO:0098660 inorganic ion transmembrane transport 1.9% (4/210) 2.4 0.003046 0.012589
GO:0034220 ion transmembrane transport 1.9% (4/210) 2.4 0.003046 0.012589
GO:1902600 proton transmembrane transport 1.9% (4/210) 2.4 0.003046 0.012589
GO:0098655 cation transmembrane transport 1.9% (4/210) 2.4 0.003046 0.012589
GO:0098662 inorganic cation transmembrane transport 1.9% (4/210) 2.4 0.003046 0.012589
GO:1901566 organonitrogen compound biosynthetic process 3.33% (7/210) 1.7 0.002997 0.013177
GO:0005737 cytoplasm 3.33% (7/210) 1.7 0.002997 0.013177
GO:0006082 organic acid metabolic process 3.81% (8/210) 1.52 0.003784 0.015452
GO:1901576 organic substance biosynthetic process 5.71% (12/210) 1.17 0.004223 0.017041
GO:0019438 aromatic compound biosynthetic process 2.86% (6/210) 1.76 0.004775 0.018825
GO:1901135 carbohydrate derivative metabolic process 2.86% (6/210) 1.76 0.004775 0.018825
GO:0000166 nucleotide binding 12.38% (26/210) 0.72 0.005212 0.020086
GO:1901265 nucleoside phosphate binding 12.38% (26/210) 0.72 0.005212 0.020086
GO:0005488 binding 20.48% (43/210) 0.52 0.005466 0.020832
GO:0043168 anion binding 12.38% (26/210) 0.71 0.005834 0.021989
GO:0009987 cellular process 14.76% (31/210) 0.62 0.006477 0.02415
GO:0003924 GTPase activity 1.43% (3/210) 2.57 0.007261 0.025156
GO:0017111 nucleoside-triphosphatase activity 1.43% (3/210) 2.57 0.007261 0.025156
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.43% (3/210) 2.57 0.007261 0.025156
GO:0016817 hydrolase activity, acting on acid anhydrides 1.43% (3/210) 2.57 0.007261 0.025156
GO:0016462 pyrophosphatase activity 1.43% (3/210) 2.57 0.007261 0.025156
GO:0018130 heterocycle biosynthetic process 2.86% (6/210) 1.66 0.007131 0.026019
GO:1901362 organic cyclic compound biosynthetic process 2.86% (6/210) 1.66 0.007131 0.026019
GO:0006793 phosphorus metabolic process 3.33% (7/210) 1.47 0.008546 0.029022
GO:0006796 phosphate-containing compound metabolic process 3.33% (7/210) 1.47 0.008546 0.029022
GO:1901363 heterocyclic compound binding 18.1% (38/210) 0.52 0.008872 0.029544
GO:0097159 organic cyclic compound binding 18.1% (38/210) 0.52 0.008872 0.029544
GO:0044249 cellular biosynthetic process 5.24% (11/210) 1.08 0.010177 0.033566
GO:0036094 small molecule binding 12.38% (26/210) 0.64 0.011003 0.035942
GO:0098796 membrane protein complex 1.9% (4/210) 1.98 0.011553 0.037382
GO:0030554 adenyl nucleotide binding 10.48% (22/210) 0.67 0.014364 0.045201
GO:0032559 adenyl ribonucleotide binding 10.48% (22/210) 0.67 0.014364 0.045201
GO:0005524 ATP binding 10.48% (22/210) 0.67 0.014364 0.045201
GO:0019843 rRNA binding 0.95% (2/210) 2.98 0.015956 0.049307
GO:0004820 glycine-tRNA ligase activity 0.95% (2/210) 2.98 0.015956 0.049307
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_1 0.03 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_3 0.029 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_8 0.09 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_2 0.109 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_12 0.03 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_15 0.035 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_19 0.031 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_30 0.036 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_31 0.036 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_1 0.027 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_2 0.051 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_3 0.04 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_5 0.045 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_6 0.028 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_7 0.063 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_12 0.057 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_13 0.041 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_15 0.047 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_18 0.05 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_21 0.05 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_26 0.039 OrthoFinder Compare
Escherichia coli HCCA Cluster_1 0.122 OrthoFinder Compare
Escherichia coli HCCA Cluster_37 0.043 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_3 0.029 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_7 0.027 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_8 0.029 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_11 0.036 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_17 0.083 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_19 0.028 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_9 0.08 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_14 0.031 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_2 0.031 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_9 0.033 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_12 0.075 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_26 0.033 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_37 0.034 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_38 0.041 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_44 0.034 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_2 0.094 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_4 0.03 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_7 0.043 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_18 0.092 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_20 0.028 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_21 0.032 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_24 0.03 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_26 0.058 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_1 0.042 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_3 0.038 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_5 0.07 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_25 0.076 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_5 0.041 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_6 0.056 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_7 0.035 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.05 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_16 0.027 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_17 0.032 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_22 0.095 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_34 0.031 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_35 0.039 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_47 0.027 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_63 0.029 OrthoFinder Compare
Salmonella enterica HCCA Cluster_23 0.112 OrthoFinder Compare
Salmonella enterica HCCA Cluster_31 0.044 OrthoFinder Compare
Salmonella enterica HCCA Cluster_35 0.043 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_5 0.04 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_6 0.027 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_9 0.035 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_10 0.042 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_15 0.035 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_17 0.038 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_19 0.062 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_24 0.096 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_25 0.039 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_2 0.046 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_3 0.079 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_4 0.038 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_7 0.076 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_8 0.03 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_13 0.081 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.071 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_15 0.033 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_16 0.029 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_18 0.076 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_19 0.035 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_20 0.029 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_1 0.036 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_5 0.036 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_8 0.102 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_24 0.04 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_31 0.027 OrthoFinder Compare
Sequences (210) (download table)

InterPro Domains

GO Terms

Family Terms