CCL19868 (cobA + hemD, BN171_3580003)

Aliases : cobA + hemD, BN171_3580003

Description : Bifunctional uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase [Ensembl]. Tetrapyrrole (Corrin/Porphyrin) Methylases, Uroporphyrinogen-III synthase HemD [Interproscan].

Gene families : OG_02_0000411 (OrthoFinder) Phylogenetic Tree(s): OG0000411_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCL19868
Cluster	HCCA: Cluster_12

Target	Alias	Description	ECC score	Gene Family Method
AAL20933	STM2029, cbiF	synthesis of vitamin B12 adenosyl cobalamide precursor...	0.11	OrthoFinder
AGT22826	N559_1047	hypothetical protein [Ensembl]. Tetrapyrrole...	0.06	OrthoFinder
AKI49125	cbiF, L2625_01214	precorrin-4 C11-methyltransferase [Ensembl]....	0.1	OrthoFinder
AKI49129	cobA, L2625_01218	uroporphyrin-III...	0.1	OrthoFinder
CCP43248	hemD, Rv0511	Probable uroporphyrin-III C-methyltransferase HemD...	0.03	OrthoFinder
CCP45648	cysG, Rv2847c	Possible multifunctional enzyme siroheme synthase CysG:...	0.03	OrthoFinder
CPC85423	hemD, ERS093114_01491	uroporphyrinogen III synthase [Ensembl]....	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016835	carbon-oxygen lyase activity	None	Extended
MF	GO:0016836	hydro-lyase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	IEA	Interproscan
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004418	hydroxymethylbilane synthase activity	IEP	Enrichment
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
BP	GO:0006766	vitamin metabolic process	IEP	Enrichment
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Enrichment
MF	GO:0008172	S-methyltransferase activity	IEP	Enrichment
MF	GO:0008705	methionine synthase activity	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
BP	GO:0009235	cobalamin metabolic process	IEP	Enrichment
BP	GO:0009236	cobalamin biosynthetic process	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Enrichment
MF	GO:0016852	sirohydrochlorin cobaltochelatase activity	IEP	Enrichment
MF	GO:0016994	precorrin-6A reductase activity	IEP	Enrichment
BP	GO:0019251	anaerobic cobalamin biosynthetic process	IEP	Enrichment
MF	GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR003754	4pyrrol_synth_uPrphyn_synth	266	493
IPR000878	4pyrrol_Mease	4	214

External Links

UniProtKB	U3X0R9

CCL19868 (cobA + hemD, BN171_3580003)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation