CCL19869 (hemC, BN171_3580004)

Aliases : hemC, BN171_3580004

Description : Porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) [Ensembl]. Porphobilinogen deaminase [Interproscan].

Gene families : OG_02_0000916 (OrthoFinder) Phylogenetic Tree(s): OG0000916_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CCL19869
Cluster	HCCA: Cluster_12

Target	Alias	Description	ECC score	Gene Family Method	Actions
CCP43247	hemC, Rv0510	Probable porphobilinogen deaminase HemC (PBG)...	0.02	OrthoFinder
CPC85464	hemC, ERS093114_01492	porphobilinogen deaminase [Ensembl]. Porphobilinogen...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004418	hydroxymethylbilane synthase activity	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	IEA	Interproscan
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEP	Enrichment
BP	GO:0006766	vitamin metabolic process	IEP	Enrichment
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Enrichment
MF	GO:0008168	methyltransferase activity	IEP	Enrichment
MF	GO:0008172	S-methyltransferase activity	IEP	Enrichment
MF	GO:0008705	methionine synthase activity	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
BP	GO:0009235	cobalamin metabolic process	IEP	Enrichment
BP	GO:0009236	cobalamin biosynthetic process	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016835	carbon-oxygen lyase activity	IEP	Enrichment
MF	GO:0016836	hydro-lyase activity	IEP	Enrichment
MF	GO:0016852	sirohydrochlorin cobaltochelatase activity	IEP	Enrichment
MF	GO:0016994	precorrin-6A reductase activity	IEP	Enrichment
BP	GO:0019251	anaerobic cobalamin biosynthetic process	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR022417	Porphobilin_deaminase_N	3	210
IPR022418	Porphobilinogen_deaminase_C	225	293

External Links

UniProtKB	U3X093

CCL19869 (hemC, BN171_3580004)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation