CRP39831 (cysG_2)

Aliases : cysG_2

Description : Siroheme synthase [Ensembl]. Putative NAD(P)-binding, Sirohaem synthase dimerisation region, Sirohaem biosynthesis protein central, Tetrapyrrole (Corrin/Porphyrin) Methylases [Interproscan].

Gene families : OG_02_0000411 (OrthoFinder) Phylogenetic Tree(s): OG0000411_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CRP39831
Cluster	HCCA: Cluster_59

Target	Alias	Description	ECC score	Gene Family Method	Actions
AKI49552	hemD, L2625_01660	uroporphyrinogen-III synthase [Ensembl]. Tetrapyrrole...	0.03	OrthoFinder
CPC85423	hemD, ERS093114_01491	uroporphyrinogen III synthase [Ensembl]....	0.02	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006778	porphyrin-containing compound metabolic process	None	Extended
BP	GO:0006779	porphyrin-containing compound biosynthetic process	IEA	Interproscan
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055114	obsolete oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
BP	GO:0000105	histidine biosynthetic process	IEP	Enrichment
MF	GO:0000166	nucleotide binding	IEP	Enrichment
BP	GO:0001522	pseudouridine synthesis	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0003909	DNA ligase activity	IEP	Enrichment
MF	GO:0003911	DNA ligase (NAD+) activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004177	aminopeptidase activity	IEP	Enrichment
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Enrichment
MF	GO:0004665	prephenate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006281	DNA repair	IEP	Enrichment
BP	GO:0006298	mismatch repair	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006534	cysteine metabolic process	IEP	Enrichment
BP	GO:0006547	histidine metabolic process	IEP	Enrichment
BP	GO:0006570	tyrosine metabolic process	IEP	Enrichment
BP	GO:0006571	tyrosine biosynthetic process	IEP	Enrichment
BP	GO:0006643	membrane lipid metabolic process	IEP	Enrichment
BP	GO:0006644	phospholipid metabolic process	IEP	Enrichment
BP	GO:0006664	glycolipid metabolic process	IEP	Enrichment
BP	GO:0006950	response to stress	IEP	Enrichment
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
MF	GO:0008408	3'-5' exonuclease activity	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Enrichment
BP	GO:0008654	phospholipid biosynthetic process	IEP	Enrichment
MF	GO:0008915	lipid-A-disaccharide synthase activity	IEP	Enrichment
MF	GO:0008977	prephenate dehydrogenase (NAD+) activity	IEP	Enrichment
MF	GO:0009029	tetraacyldisaccharide 4'-kinase activity	IEP	Enrichment
BP	GO:0009092	homoserine metabolic process	IEP	Enrichment
BP	GO:0009095	aromatic amino acid family biosynthetic process, prephenate pathway	IEP	Enrichment
BP	GO:0009245	lipid A biosynthetic process	IEP	Enrichment
BP	GO:0009247	glycolipid biosynthetic process	IEP	Enrichment
BP	GO:0009311	oligosaccharide metabolic process	IEP	Enrichment
BP	GO:0009312	oligosaccharide biosynthetic process	IEP	Enrichment
CC	GO:0009360	DNA polymerase III complex	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
BP	GO:0016051	carbohydrate biosynthetic process	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0019346	transsulfuration	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0033554	cellular response to stress	IEP	Enrichment
MF	GO:0034061	DNA polymerase activity	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
CC	GO:0042575	DNA polymerase complex	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043167	ion binding	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046467	membrane lipid biosynthetic process	IEP	Enrichment
BP	GO:0046493	lipid A metabolic process	IEP	Enrichment
MF	GO:0046872	metal ion binding	IEP	Enrichment
BP	GO:0050667	homocysteine metabolic process	IEP	Enrichment
BP	GO:0051716	cellular response to stimulus	IEP	Enrichment
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
CC	GO:0140535	intracellular protein-containing complex	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901269	lipooligosaccharide metabolic process	IEP	Enrichment
BP	GO:1901271	lipooligosaccharide biosynthetic process	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
BP	GO:1903509	liposaccharide metabolic process	IEP	Enrichment
CC	GO:1990234	transferase complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR019478	Sirohaem_synthase_dimer_dom	151	207
IPR028281	Sirohaem_synthase_central	119	144
IPR000878	4pyrrol_Mease	219	428

External Links

Locus_tag	PAERUG_E11_London_26_VIM_2_06_13_05273

CRP39831 (cysG_2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation