Coexpression cluster: Cluster_1 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:1902600 proton transmembrane transport 5.84% (8/137) 4.87 0.0 0.0
GO:0098655 cation transmembrane transport 5.84% (8/137) 4.7 0.0 0.0
GO:0098660 inorganic ion transmembrane transport 5.84% (8/137) 4.7 0.0 0.0
GO:0034220 ion transmembrane transport 5.84% (8/137) 4.7 0.0 0.0
GO:0098662 inorganic cation transmembrane transport 5.84% (8/137) 4.7 0.0 0.0
GO:0015986 ATP synthesis coupled proton transport 4.38% (6/137) 4.87 0.0 0.0
GO:0009141 nucleoside triphosphate metabolic process 4.38% (6/137) 4.87 0.0 0.0
GO:0009142 nucleoside triphosphate biosynthetic process 4.38% (6/137) 4.87 0.0 0.0
GO:0009144 purine nucleoside triphosphate metabolic process 4.38% (6/137) 4.87 0.0 0.0
GO:0009145 purine nucleoside triphosphate biosynthetic process 4.38% (6/137) 4.87 0.0 0.0
GO:0009205 purine ribonucleoside triphosphate metabolic process 4.38% (6/137) 4.87 0.0 0.0
GO:0009201 ribonucleoside triphosphate biosynthetic process 4.38% (6/137) 4.87 0.0 0.0
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 4.38% (6/137) 4.87 0.0 0.0
GO:0009199 ribonucleoside triphosphate metabolic process 4.38% (6/137) 4.87 0.0 0.0
GO:0006754 ATP biosynthetic process 4.38% (6/137) 4.87 0.0 0.0
GO:0015985 energy coupled proton transport, down electrochemical gradient 4.38% (6/137) 4.87 0.0 0.0
GO:0046034 ATP metabolic process 5.11% (7/137) 4.22 0.0 0.0
GO:0009152 purine ribonucleotide biosynthetic process 4.38% (6/137) 4.46 0.0 1e-06
GO:0046390 ribose phosphate biosynthetic process 4.38% (6/137) 4.46 0.0 1e-06
GO:0009260 ribonucleotide biosynthetic process 4.38% (6/137) 4.46 0.0 1e-06
GO:0015078 proton transmembrane transporter activity 4.38% (6/137) 4.29 0.0 1e-06
GO:0006164 purine nucleotide biosynthetic process 4.38% (6/137) 4.14 0.0 3e-06
GO:0072522 purine-containing compound biosynthetic process 4.38% (6/137) 4.14 0.0 3e-06
GO:1901137 carbohydrate derivative biosynthetic process 4.38% (6/137) 4.14 0.0 3e-06
GO:0006812 cation transport 5.84% (8/137) 3.35 0.0 5e-06
GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain 2.92% (4/137) 4.87 1e-06 1.4e-05
GO:0019693 ribose phosphate metabolic process 4.38% (6/137) 3.65 3e-06 3.3e-05
GO:0009150 purine ribonucleotide metabolic process 4.38% (6/137) 3.65 3e-06 3.3e-05
GO:0009259 ribonucleotide metabolic process 4.38% (6/137) 3.65 3e-06 3.3e-05
GO:0006811 ion transport 5.84% (8/137) 2.97 5e-06 4.4e-05
GO:0022890 inorganic cation transmembrane transporter activity 4.38% (6/137) 3.55 5e-06 5e-05
GO:0072521 purine-containing compound metabolic process 4.38% (6/137) 3.46 9e-06 7.3e-05
GO:0006163 purine nucleotide metabolic process 4.38% (6/137) 3.46 9e-06 7.3e-05
GO:1901135 carbohydrate derivative metabolic process 5.84% (8/137) 2.7 2e-05 0.000167
GO:0051276 chromosome organization 2.19% (3/137) 4.87 3.9e-05 0.000297
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) 2.19% (3/137) 4.87 3.9e-05 0.000297
GO:0006996 organelle organization 2.19% (3/137) 4.87 3.9e-05 0.000297
GO:0008324 cation transmembrane transporter activity 4.38% (6/137) 3.07 5e-05 0.000373
GO:0015318 inorganic molecular entity transmembrane transporter activity 4.38% (6/137) 3.0 6.7e-05 0.000486
GO:0098796 membrane protein complex 3.65% (5/137) 3.2 0.000138 0.000978
GO:1901293 nucleoside phosphate biosynthetic process 4.38% (6/137) 2.82 0.000146 0.000984
GO:0009165 nucleotide biosynthetic process 4.38% (6/137) 2.82 0.000146 0.000984
GO:0016651 oxidoreductase activity, acting on NAD(P)H 2.19% (3/137) 4.46 0.000151 0.000996
GO:0015075 ion transmembrane transporter activity 4.38% (6/137) 2.76 0.000185 0.001187
GO:0090407 organophosphate biosynthetic process 5.11% (7/137) 2.32 0.000391 0.002461
GO:0055086 nucleobase-containing small molecule metabolic process 5.11% (7/137) 2.29 0.000456 0.002808
GO:0009117 nucleotide metabolic process 4.38% (6/137) 2.5 0.000513 0.003024
GO:0006753 nucleoside phosphate metabolic process 4.38% (6/137) 2.5 0.000513 0.003024
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity 1.46% (2/137) 4.87 0.001154 0.00594
GO:0006265 DNA topological change 1.46% (2/137) 4.87 0.001154 0.00594
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1.46% (2/137) 4.87 0.001154 0.00594
GO:0003916 DNA topoisomerase activity 1.46% (2/137) 4.87 0.001154 0.00594
GO:0015252 proton channel activity 1.46% (2/137) 4.87 0.001154 0.00594
GO:0005261 cation channel activity 1.46% (2/137) 4.87 0.001154 0.00594
GO:0071103 DNA conformation change 1.46% (2/137) 4.87 0.001154 0.00594
GO:0032991 protein-containing complex 3.65% (5/137) 2.55 0.001312 0.006631
GO:0006796 phosphate-containing compound metabolic process 5.84% (8/137) 1.83 0.001609 0.007852
GO:0006793 phosphorus metabolic process 5.84% (8/137) 1.83 0.001609 0.007852
GO:0034654 nucleobase-containing compound biosynthetic process 4.38% (6/137) 2.17 0.001816 0.008713
GO:0019637 organophosphate metabolic process 5.11% (7/137) 1.95 0.001908 0.008998
GO:0022803 passive transmembrane transporter activity 1.46% (2/137) 4.29 0.003386 0.013886
GO:0003955 NAD(P)H dehydrogenase (quinone) activity 1.46% (2/137) 4.29 0.003386 0.013886
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1.46% (2/137) 4.29 0.003386 0.013886
GO:0008137 NADH dehydrogenase (ubiquinone) activity 1.46% (2/137) 4.29 0.003386 0.013886
GO:0003954 NADH dehydrogenase activity 1.46% (2/137) 4.29 0.003386 0.013886
GO:0005216 ion channel activity 1.46% (2/137) 4.29 0.003386 0.013886
GO:0050136 NADH dehydrogenase (quinone) activity 1.46% (2/137) 4.29 0.003386 0.013886
GO:0015267 channel activity 1.46% (2/137) 4.29 0.003386 0.013886
GO:0008610 lipid biosynthetic process 3.65% (5/137) 2.24 0.00356 0.014394
GO:0009055 electron transfer activity 2.92% (4/137) 2.63 0.003364 0.015607
GO:0044238 primary metabolic process 16.06% (22/137) 0.84 0.004716 0.018538
GO:1901362 organic cyclic compound biosynthetic process 5.84% (8/137) 1.59 0.004661 0.018578
GO:0055085 transmembrane transport 5.84% (8/137) 1.57 0.00504 0.019539
GO:0019438 aromatic compound biosynthetic process 5.11% (7/137) 1.7 0.00516 0.019733
GO:0006139 nucleobase-containing compound metabolic process 8.76% (12/137) 1.17 0.006369 0.024033
GO:0016043 cellular component organization 2.19% (3/137) 2.87 0.006805 0.025341
GO:1901360 organic cyclic compound metabolic process 10.22% (14/137) 1.04 0.007547 0.027737
GO:0006725 cellular aromatic compound metabolic process 9.49% (13/137) 1.02 0.010971 0.039807
GO:0008152 metabolic process 18.98% (26/137) 0.65 0.011496 0.041182
GO:0009058 biosynthetic process 10.22% (14/137) 0.95 0.012338 0.043644
GO:0071840 cellular component organization or biogenesis 2.19% (3/137) 2.55 0.01306 0.045628
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Clostridioides difficile HCCA Cluster_31 0.051 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_5 0.04 OrthoFinder Compare
Escherichia coli HCCA Cluster_1 0.044 OrthoFinder Compare
Escherichia coli HCCA Cluster_6 0.04 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_12 0.036 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_29 0.03 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_7 0.032 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_14 0.037 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_3 0.041 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_10 0.033 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_14 0.033 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_23 0.028 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_27 0.033 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_32 0.03 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_36 0.028 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_22 0.043 OrthoFinder Compare
Salmonella enterica HCCA Cluster_6 0.058 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_12 0.047 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.044 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_9 0.044 OrthoFinder Compare
Sequences (137) (download table)

InterPro Domains

GO Terms

Family Terms