Coexpression cluster: Cluster_1 (HCCA)

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0006412 translation 25.23% (27/107) 4.57 0.0 0.0
GO:0003735 structural constituent of ribosome 25.23% (27/107) 4.54 0.0 0.0
GO:0043043 peptide biosynthetic process 25.23% (27/107) 4.47 0.0 0.0
GO:0005840 ribosome 24.3% (26/107) 4.55 0.0 0.0
GO:0006518 peptide metabolic process 25.23% (27/107) 4.44 0.0 0.0
GO:0005198 structural molecule activity 25.23% (27/107) 4.41 0.0 0.0
GO:0043604 amide biosynthetic process 25.23% (27/107) 4.41 0.0 0.0
GO:0043232 intracellular non-membrane-bounded organelle 24.3% (26/107) 4.48 0.0 0.0
GO:0043229 intracellular organelle 24.3% (26/107) 4.48 0.0 0.0
GO:0043603 cellular amide metabolic process 25.23% (27/107) 4.33 0.0 0.0
GO:0044271 cellular nitrogen compound biosynthetic process 32.71% (35/107) 3.6 0.0 0.0
GO:0043226 organelle 24.3% (26/107) 4.36 0.0 0.0
GO:0043228 non-membrane-bounded organelle 24.3% (26/107) 4.36 0.0 0.0
GO:0044267 cellular protein metabolic process 25.23% (27/107) 4.22 0.0 0.0
GO:0034645 cellular macromolecule biosynthetic process 27.1% (29/107) 3.83 0.0 0.0
GO:1901566 organonitrogen compound biosynthetic process 31.78% (34/107) 3.36 0.0 0.0
GO:0009059 macromolecule biosynthetic process 27.1% (29/107) 3.67 0.0 0.0
GO:0044249 cellular biosynthetic process 34.58% (37/107) 2.88 0.0 0.0
GO:1901576 organic substance biosynthetic process 34.58% (37/107) 2.8 0.0 0.0
GO:0019538 protein metabolic process 25.23% (27/107) 3.47 0.0 0.0
GO:0009058 biosynthetic process 34.58% (37/107) 2.53 0.0 0.0
GO:0034641 cellular nitrogen compound metabolic process 36.45% (39/107) 2.26 0.0 0.0
GO:1901564 organonitrogen compound metabolic process 32.71% (35/107) 2.37 0.0 0.0
GO:0044237 cellular metabolic process 42.99% (46/107) 1.81 0.0 0.0
GO:0044260 cellular macromolecule metabolic process 27.1% (29/107) 2.52 0.0 0.0
GO:1902600 proton transmembrane transport 7.48% (8/107) 5.27 0.0 0.0
GO:0006807 nitrogen compound metabolic process 36.45% (39/107) 1.77 0.0 0.0
GO:0043170 macromolecule metabolic process 29.91% (32/107) 1.97 0.0 0.0
GO:0098662 inorganic cation transmembrane transport 7.48% (8/107) 4.95 0.0 0.0
GO:0098660 inorganic ion transmembrane transport 7.48% (8/107) 4.95 0.0 0.0
GO:0098655 cation transmembrane transport 7.48% (8/107) 4.81 0.0 0.0
GO:0044238 primary metabolic process 37.38% (40/107) 1.57 0.0 0.0
GO:0008152 metabolic process 43.93% (47/107) 1.36 0.0 0.0
GO:0009145 purine nucleoside triphosphate biosynthetic process 5.61% (6/107) 5.27 0.0 0.0
GO:0009201 ribonucleoside triphosphate biosynthetic process 5.61% (6/107) 5.27 0.0 0.0
GO:0009205 purine ribonucleoside triphosphate metabolic process 5.61% (6/107) 5.27 0.0 0.0
GO:0009199 ribonucleoside triphosphate metabolic process 5.61% (6/107) 5.27 0.0 0.0
GO:0009142 nucleoside triphosphate biosynthetic process 5.61% (6/107) 5.27 0.0 0.0
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 5.61% (6/107) 5.27 0.0 0.0
GO:0015985 energy coupled proton transport, down electrochemical gradient 5.61% (6/107) 5.27 0.0 0.0
GO:0015986 ATP synthesis coupled proton transport 5.61% (6/107) 5.27 0.0 0.0
GO:0006754 ATP biosynthetic process 5.61% (6/107) 5.27 0.0 0.0
GO:0009144 purine nucleoside triphosphate metabolic process 5.61% (6/107) 5.27 0.0 0.0
GO:0071704 organic substance metabolic process 39.25% (42/107) 1.41 0.0 0.0
GO:0005575 cellular_component 40.19% (43/107) 1.39 0.0 0.0
GO:0009260 ribonucleotide biosynthetic process 6.54% (7/107) 4.76 0.0 0.0
GO:0009152 purine ribonucleotide biosynthetic process 6.54% (7/107) 4.76 0.0 0.0
GO:0046390 ribose phosphate biosynthetic process 6.54% (7/107) 4.76 0.0 0.0
GO:0009987 cellular process 50.47% (54/107) 1.09 0.0 0.0
GO:0009141 nucleoside triphosphate metabolic process 5.61% (6/107) 5.05 0.0 0.0
GO:0006164 purine nucleotide biosynthetic process 6.54% (7/107) 4.5 0.0 0.0
GO:0022890 inorganic cation transmembrane transporter activity 8.41% (9/107) 3.8 0.0 0.0
GO:0046034 ATP metabolic process 6.54% (7/107) 4.38 0.0 0.0
GO:0072522 purine-containing compound biosynthetic process 6.54% (7/107) 4.38 0.0 0.0
GO:0006812 cation transport 9.35% (10/107) 3.43 0.0 0.0
GO:0015078 proton transmembrane transporter activity 6.54% (7/107) 4.27 0.0 0.0
GO:0110165 cellular anatomical entity 35.51% (38/107) 1.28 0.0 0.0
GO:0015318 inorganic molecular entity transmembrane transporter activity 8.41% (9/107) 3.44 0.0 0.0
GO:0008324 cation transmembrane transporter activity 8.41% (9/107) 3.36 0.0 1e-06
GO:0034220 ion transmembrane transport 7.48% (8/107) 3.63 0.0 1e-06
GO:0009259 ribonucleotide metabolic process 6.54% (7/107) 3.91 0.0 1e-06
GO:0009150 purine ribonucleotide metabolic process 6.54% (7/107) 3.91 0.0 1e-06
GO:0019693 ribose phosphate metabolic process 6.54% (7/107) 3.91 0.0 1e-06
GO:0009165 nucleotide biosynthetic process 6.54% (7/107) 3.83 0.0 1e-06
GO:1901293 nucleoside phosphate biosynthetic process 6.54% (7/107) 3.83 0.0 1e-06
GO:0006163 purine nucleotide metabolic process 6.54% (7/107) 3.76 0.0 2e-06
GO:0072521 purine-containing compound metabolic process 6.54% (7/107) 3.69 1e-06 2e-06
GO:0090407 organophosphate biosynthetic process 7.48% (8/107) 3.19 2e-06 7e-06
GO:0019843 rRNA binding 3.74% (4/107) 4.95 2e-06 9e-06
GO:0006811 ion transport 9.35% (10/107) 2.64 3e-06 1.3e-05
GO:1901137 carbohydrate derivative biosynthetic process 6.54% (7/107) 3.33 4e-06 1.5e-05
GO:0034654 nucleobase-containing compound biosynthetic process 7.48% (8/107) 3.03 4e-06 1.6e-05
GO:0015075 ion transmembrane transporter activity 8.41% (9/107) 2.74 5e-06 2.2e-05
GO:0009117 nucleotide metabolic process 6.54% (7/107) 3.22 6e-06 2.5e-05
GO:0019637 organophosphate metabolic process 8.41% (9/107) 2.72 6e-06 2.5e-05
GO:0003674 molecular_function 65.42% (70/107) 0.57 6e-06 2.5e-05
GO:0098796 membrane protein complex 4.67% (5/107) 4.01 7e-06 2.8e-05
GO:0008150 biological_process 56.07% (60/107) 0.67 7e-06 2.8e-05
GO:0006753 nucleoside phosphate metabolic process 6.54% (7/107) 3.17 8e-06 3e-05
GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain 2.8% (3/107) 5.27 1.7e-05 6.3e-05
GO:0003723 RNA binding 8.41% (9/107) 2.49 2.4e-05 8.8e-05
GO:0006796 phosphate-containing compound metabolic process 8.41% (9/107) 2.44 3.1e-05 0.000113
GO:0055086 nucleobase-containing small molecule metabolic process 7.48% (8/107) 2.6 3.9e-05 0.00014
GO:0006793 phosphorus metabolic process 8.41% (9/107) 2.34 5.7e-05 0.000203
GO:0019438 aromatic compound biosynthetic process 7.48% (8/107) 2.42 0.0001 0.000349
GO:1901135 carbohydrate derivative metabolic process 8.41% (9/107) 2.23 0.0001 0.000352
GO:0018130 heterocycle biosynthetic process 7.48% (8/107) 2.19 0.000312 0.001074
GO:1901362 organic cyclic compound biosynthetic process 7.48% (8/107) 2.12 0.000422 0.001433
GO:0005261 cation channel activity 1.87% (2/107) 5.27 0.000662 0.002019
GO:0016675 oxidoreductase activity, acting on a heme group of donors 1.87% (2/107) 5.27 0.000662 0.002019
GO:0004129 cytochrome-c oxidase activity 1.87% (2/107) 5.27 0.000662 0.002019
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1.87% (2/107) 5.27 0.000662 0.002019
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) 1.87% (2/107) 5.27 0.000662 0.002019
GO:0015252 proton channel activity 1.87% (2/107) 5.27 0.000662 0.002019
GO:0008556 P-type potassium transmembrane transporter activity 1.87% (2/107) 5.27 0.000662 0.002019
GO:0140358 P-type transmembrane transporter activity 1.87% (2/107) 5.27 0.000662 0.002019
GO:0019829 ATPase-coupled cation transmembrane transporter activity 1.87% (2/107) 5.27 0.000662 0.002019
GO:0015662 P-type ion transporter activity 1.87% (2/107) 5.27 0.000662 0.002019
GO:0003924 GTPase activity 2.8% (3/107) 3.86 0.000855 0.002583
GO:0032991 protein-containing complex 4.67% (5/107) 2.6 0.001212 0.003625
GO:0005525 GTP binding 3.74% (4/107) 2.95 0.001485 0.004396
GO:0015079 potassium ion transmembrane transporter activity 1.87% (2/107) 4.69 0.001952 0.005722
GO:0019001 guanyl nucleotide binding 3.74% (4/107) 2.81 0.002155 0.006194
GO:0032561 guanyl ribonucleotide binding 3.74% (4/107) 2.81 0.002155 0.006194
GO:0017111 nucleoside-triphosphatase activity 2.8% (3/107) 3.4 0.002381 0.006781
GO:0006091 generation of precursor metabolites and energy 2.8% (3/107) 2.95 0.00609 0.017178
GO:0016462 pyrophosphatase activity 2.8% (3/107) 2.77 0.008766 0.024497
GO:0005216 ion channel activity 1.87% (2/107) 3.69 0.009275 0.025679
GO:0006725 cellular aromatic compound metabolic process 13.08% (14/107) 0.99 0.009833 0.026974
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.8% (3/107) 2.54 0.013894 0.037768
GO:0016817 hydrolase activity, acting on acid anhydrides 2.8% (3/107) 2.4 0.018083 0.048709
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
Campylobacter jejuni HCCA Cluster_2 0.049 OrthoFinder Compare
Campylobacter jejuni HCCA Cluster_8 0.149 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_2 0.151 OrthoFinder Compare
Clostridioides difficile HCCA Cluster_31 0.045 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_5 0.04 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_7 0.083 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_12 0.059 OrthoFinder Compare
Enterococcus faecalis HCCA Cluster_18 0.078 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_3 0.028 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_7 0.037 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_8 0.028 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_17 0.213 OrthoFinder Compare
Haemophilus influenzae HCCA Cluster_18 0.027 OrthoFinder Compare
Helicobacter pylori HCCA Cluster_9 0.196 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_12 0.25 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_21 0.029 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_34 0.075 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_35 0.028 OrthoFinder Compare
Klebsiella pneumoniae HCCA Cluster_38 0.054 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_2 0.152 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_7 0.037 OrthoFinder Compare
Listeria monocytogenes HCCA Cluster_18 0.083 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_1 0.042 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_3 0.074 OrthoFinder Compare
Mycoplasma pneumoniae HCAA Cluster_5 0.127 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_1 0.044 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_6 0.032 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_25 0.115 OrthoFinder Compare
Mycobacterium tuberculosis HCCA Cluster_33 0.028 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_5 0.063 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_6 0.089 OrthoFinder Compare
Neisseria gonorrhoeae HCCA Cluster_12 0.075 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_14 0.036 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_18 0.03 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_22 0.162 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_37 0.037 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_38 0.033 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_51 0.067 OrthoFinder Compare
Pseudomonas aeruginosa HCCA Cluster_63 0.042 OrthoFinder Compare
Salmonella enterica HCCA Cluster_5 0.033 OrthoFinder Compare
Salmonella enterica HCCA Cluster_6 0.063 OrthoFinder Compare
Salmonella enterica HCCA Cluster_12 0.035 OrthoFinder Compare
Salmonella enterica HCCA Cluster_23 0.368 OrthoFinder Compare
Salmonella enterica HCCA Cluster_44 0.039 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_12 0.086 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_19 0.047 OrthoFinder Compare
Staphylococcus aureus HCCA Cluster_24 0.254 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_7 0.137 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_13 0.122 OrthoFinder Compare
Streptococcus pneumoniae HCCA Cluster_14 0.035 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_4 0.122 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_7 0.043 OrthoFinder Compare
Streptococcus pyogenes HCAA Cluster_11 0.048 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_8 0.316 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_9 0.05 OrthoFinder Compare
Vibrio cholerae HCCA Cluster_24 0.078 OrthoFinder Compare
Sequences (107) (download table)

InterPro Domains

GO Terms

Family Terms