AAC75375 (folC, b2315)


Aliases : folC, b2315

Description : bifunctional folylpolyglutamate synthase/ dihydrofolate synthase [Ensembl]. Mur ligase family, Mur ligase middle domain [Interproscan].


Gene families : OG_02_0000331 (OrthoFinder) Phylogenetic Tree(s): OG0000331_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAC75375
Cluster HCCA: Cluster_29

Target Alias Description ECC score Gene Family Method Actions
AAL21266 STM2365, folC folylpolyglutamate synthase [Ensembl]. Mur ligase... 0.1 OrthoFinder
AGT23298 N559_1546 bifunctional folylpolyglutamate synthase/ dihydrofolate... 0.07 OrthoFinder
AKI49548 folC, L2625_01655 folylpolyglutamate synthase [Ensembl]. Mur ligase [Interproscan]. 0.05 OrthoFinder
AKP15641 folC, WX61_01603 Bifunctional protein FolC [Ensembl]. Mur ligase middle... 0.06 OrthoFinder
CCG27573 No alias Dihydrofolate synthase / Folylpolyglutamate synthase... 0.03 OrthoFinder
CPC85166 folC, ERS093114_01484 Dihydrofolate synthase / Folylpolyglutamate synthase... 0.04 OrthoFinder
CRO43516 folC Bifunctional protein FolC [Ensembl]. Mur ligase middle... 0.05 OrthoFinder
KNA56234 VCV51_030704 folylpolyglutamate synthase/dihydrofolate synthase... 0.05 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0009058 biosynthetic process IEA Interproscan
MF GO:0016874 ligase activity IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003690 double-stranded DNA binding IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003916 DNA topoisomerase activity IEP Enrichment
MF GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEP Enrichment
MF GO:0004527 exonuclease activity IEP Enrichment
MF GO:0004652 polynucleotide adenylyltransferase activity IEP Enrichment
MF GO:0004810 tRNA adenylyltransferase activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004813 alanine-tRNA ligase activity IEP Enrichment
MF GO:0004814 arginine-tRNA ligase activity IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006265 DNA topological change IEP Enrichment
BP GO:0006298 mismatch repair IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006419 alanyl-tRNA aminoacylation IEP Enrichment
BP GO:0006420 arginyl-tRNA aminoacylation IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006996 organelle organization IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
MF GO:0008168 methyltransferase activity IEP Enrichment
MF GO:0008175 tRNA methyltransferase activity IEP Enrichment
MF GO:0008176 tRNA (guanine-N7-)-methyltransferase activity IEP Enrichment
MF GO:0008194 UDP-glycosyltransferase activity IEP Enrichment
BP GO:0008360 regulation of cell shape IEP Enrichment
MF GO:0008408 3'-5' exonuclease activity IEP Enrichment
MF GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity IEP Enrichment
MF GO:0008915 lipid-A-disaccharide synthase activity IEP Enrichment
BP GO:0009143 nucleoside triphosphate catabolic process IEP Enrichment
BP GO:0009254 peptidoglycan turnover IEP Enrichment
CC GO:0009295 nucleoid IEP Enrichment
BP GO:0009451 RNA modification IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
MF GO:0016423 tRNA (guanine) methyltransferase activity IEP Enrichment
MF GO:0016740 transferase activity IEP Enrichment
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Enrichment
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0016887 ATPase IEP Enrichment
BP GO:0022603 regulation of anatomical structure morphogenesis IEP Enrichment
BP GO:0022604 regulation of cell morphogenesis IEP Enrichment
MF GO:0030983 mismatched DNA binding IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0035596 methylthiotransferase activity IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
BP GO:0043170 macromolecule metabolic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
MF GO:0047429 nucleoside-triphosphate diphosphatase activity IEP Enrichment
MF GO:0050497 alkylthioltransferase activity IEP Enrichment
BP GO:0050793 regulation of developmental process IEP Enrichment
BP GO:0051276 chromosome organization IEP Enrichment
MF GO:0051536 iron-sulfur cluster binding IEP Enrichment
MF GO:0051540 metal cluster binding IEP Enrichment
MF GO:0070566 adenylyltransferase activity IEP Enrichment
BP GO:0071103 DNA conformation change IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
BP GO:1901292 nucleoside phosphate catabolic process IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
MF GO:1990817 RNA adenylyltransferase activity IEP Enrichment
InterPro domains Description Start Stop
IPR013221 Mur_ligase_cen 54 197
IPR004101 Mur_ligase_C 287 346
UniProtKB P08192