AKI49283 (parC, L2625_01377)

Aliases : parC, L2625_01377

Description : DNA topoisomerase IV, A subunit [Ensembl]. DNA gyrase/topoisomerase IV, DNA topoisomerase [Interproscan].

Gene families : OG_02_0002724 (OrthoFinder) Phylogenetic Tree(s): OG0002724_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKI49283
Cluster	HCCA: Cluster_18

Target	Alias	Description	ECC score	Gene Family Method
AAK99561	spr0757, parC	Topoisomerase IV subunit A [Ensembl]. DNA...	0.07	OrthoFinder
AEA94017	gyrA2, OG1RF_11330	DNA topoisomerase (ATP-hydrolyzing) subunit A [Ensembl]....	0.09	OrthoFinder
CCG27105	No alias	Topoisomerase IV subunit A [Ensembl]. DNA...	0.07	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	ATPase, acting on DNA	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
BP	GO:0001522	pseudouridine synthesis	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003735	structural constituent of ribosome	IEP	Enrichment
MF	GO:0003883	CTP synthase activity	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Enrichment
MF	GO:0004527	exonuclease activity	IEP	Enrichment
MF	GO:0004652	polynucleotide adenylyltransferase activity	IEP	Enrichment
MF	GO:0004810	tRNA adenylyltransferase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005198	structural molecule activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
CC	GO:0005840	ribosome	IEP	Enrichment
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006353	DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006412	translation	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006518	peptide metabolic process	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006528	asparagine metabolic process	IEP	Enrichment
BP	GO:0006529	asparagine biosynthetic process	IEP	Enrichment
MF	GO:0008135	translation factor activity, RNA binding	IEP	Enrichment
MF	GO:0008716	D-alanine-D-alanine ligase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009451	RNA modification	IEP	Enrichment
MF	GO:0009982	pseudouridine synthase activity	IEP	Enrichment
BP	GO:0015833	peptide transport	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016758	hexosyltransferase activity	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Enrichment
BP	GO:0017013	protein flavinylation	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0030258	lipid modification	IEP	Enrichment
BP	GO:0030259	lipid glycosylation	IEP	Enrichment
BP	GO:0031554	regulation of DNA-templated transcription, termination	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
BP	GO:0042886	amide transport	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043043	peptide biosynthetic process	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043228	non-membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Enrichment
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043412	macromolecule modification	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0043603	cellular amide metabolic process	IEP	Enrichment
BP	GO:0043604	amide biosynthetic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044267	cellular protein metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
MF	GO:0045182	translation regulator activity	IEP	Enrichment
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Enrichment
MF	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
BP	GO:0051304	chromosome separation	IEP	Enrichment
BP	GO:0052646	alditol phosphate metabolic process	IEP	Enrichment
BP	GO:0070085	glycosylation	IEP	Enrichment
BP	GO:0071705	nitrogen compound transport	IEP	Enrichment
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	Enrichment
MF	GO:0097747	RNA polymerase activity	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
MF	GO:1990817	RNA adenylyltransferase activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006691	GyrA/parC_rep	550	600
IPR006691	GyrA/parC_rep	609	652
IPR006691	GyrA/parC_rep	709	738
IPR006691	GyrA/parC_rep	657	700
IPR006691	GyrA/parC_rep	505	520
IPR002205	Topo_IIA_A/C	32	471

External Links

No external refs found!

AKI49283 (parC, L2625_01377)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation