AKP15383 (ileS, WX61_01336)

Aliases : ileS, WX61_01336

Description : Isoleucine--tRNA ligase [Ensembl]. tRNA synthetases class I (I, Anticodon-binding domain of tRNA, Zinc finger found in FPG and IleRS [Interproscan].

Gene families : OG_02_0000544 (OrthoFinder) Phylogenetic Tree(s): OG0000544_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AKP15383
Cluster	HCCA: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method
AAC73137	ileS, b0026	isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.07	OrthoFinder
AAL00306	spr1502, ileS	Isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.04	OrthoFinder
AAL19010	STM0046, ileS	isoleucine tRNA synthetase [Ensembl]. tRNA synthetases...	0.03	OrthoFinder
AGT26019	N559_4412	isoleucine--tRNA ligase [Ensembl]. Anticodon-binding...	0.03	OrthoFinder
AKI50014	ileS, L2625_02167	isoleucyl-tRNA synthetase [Ensembl]....	0.04	OrthoFinder
CPC37325	ileS, ERS093114_00231	isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.03	OrthoFinder
CRN65985	ileS	Isoleucine--tRNA ligase [Ensembl]. tRNA synthetases...	0.06	OrthoFinder
KNA57455	VCV51_030447	isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.06	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003989	acetyl-CoA carboxylase activity	IEP	Enrichment
MF	GO:0003994	aconitate hydratase activity	IEP	Enrichment
MF	GO:0004175	endopeptidase activity	IEP	Enrichment
MF	GO:0004252	serine-type endopeptidase activity	IEP	Enrichment
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Enrichment
MF	GO:0004592	pantoate-beta-alanine ligase activity	IEP	Enrichment
MF	GO:0004594	pantothenate kinase activity	IEP	Enrichment
MF	GO:0004664	prephenate dehydratase activity	IEP	Enrichment
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006558	L-phenylalanine metabolic process	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008236	serine-type peptidase activity	IEP	Enrichment
MF	GO:0008237	metallopeptidase activity	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Enrichment
MF	GO:0008897	holo-[acyl-carrier-protein] synthase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Enrichment
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Enrichment
BP	GO:0009094	L-phenylalanine biosynthetic process	IEP	Enrichment
CC	GO:0009317	acetyl-CoA carboxylase complex	IEP	Enrichment
CC	GO:0009360	DNA polymerase III complex	IEP	Enrichment
BP	GO:0010033	response to organic substance	IEP	Enrichment
MF	GO:0015128	gluconate transmembrane transporter activity	IEP	Enrichment
CC	GO:0016020	membrane	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
MF	GO:0016421	CoA carboxylase activity	IEP	Enrichment
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016744	transketolase or transaldolase activity	IEP	Enrichment
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016835	carbon-oxygen lyase activity	IEP	Enrichment
MF	GO:0016836	hydro-lyase activity	IEP	Enrichment
MF	GO:0016885	ligase activity, forming carbon-carbon bonds	IEP	Enrichment
MF	GO:0017171	serine hydrolase activity	IEP	Enrichment
BP	GO:0030258	lipid modification	IEP	Enrichment
BP	GO:0030259	lipid glycosylation	IEP	Enrichment
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Enrichment
CC	GO:0032991	protein-containing complex	IEP	Enrichment
BP	GO:0035429	gluconate transmembrane transport	IEP	Enrichment
BP	GO:0042221	response to chemical	IEP	Enrichment
CC	GO:0042575	DNA polymerase complex	IEP	Enrichment
BP	GO:0042873	aldonate transmembrane transport	IEP	Enrichment
MF	GO:0042879	aldonate transmembrane transporter activity	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046417	chorismate metabolic process	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
MF	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity	IEP	Enrichment
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Enrichment
BP	GO:0070085	glycosylation	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0072330	monocarboxylic acid biosynthetic process	IEP	Enrichment
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Enrichment
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	IEP	Enrichment
BP	GO:1902223	erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process	IEP	Enrichment
CC	GO:1902494	catalytic complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002300	aa-tRNA-synth_Ia	28	643
IPR010663	Znf_FPG/IleRS	889	917
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	706	845

External Links

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AKP15383 (ileS, WX61_01336)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation