AAL19496 (STM0542, folD)


Aliases : STM0542, folD

Description : 5,10-methylene-tetrahydrofolate dehydrogenase [Ensembl]. Tetrahydrofolate dehydrogenase/cyclohydrolase [Interproscan].


Gene families : OG_02_0000724 (OrthoFinder) Phylogenetic Tree(s): OG0000724_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AAL19496
Cluster HCCA: Cluster_31

Target Alias Description ECC score Gene Family Method Actions
AAC73631 folD, b0529 bifunctional 5,10-methylene-tetrahydrofolate... 0.17 OrthoFinder
AEA93399 folD, OG1RF_10712 bifunctional methylenetetrahydrofolate... 0.03 OrthoFinder
AHY40078 CJ8421_04255 bifunctional 5,10-methylene-tetrahydrofolate... 0.03 OrthoFinder
CCG26394 No alias Methylenetetrahydrofolate dehydrogenase (NADP+) /... 0.02 OrthoFinder
CPC41101 folD, ERS093114_00361 Methenyltetrahydrofolate cyclohydrolase [Ensembl].... 0.04 OrthoFinder
CRP57553 folD Bifunctional protein FolD protein [Ensembl].... 0.07 OrthoFinder
EDJ90266 CGSHi22421_06484 FolD bifunctional protein [Ensembl]. Tetrahydrofolate... 0.04 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA Interproscan
BP GO:0055114 obsolete oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source
BP GO:0000154 rRNA modification IEP Enrichment
MF GO:0000166 nucleotide binding IEP Enrichment
BP GO:0001510 RNA methylation IEP Enrichment
MF GO:0002161 aminoacyl-tRNA editing activity IEP Enrichment
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003887 DNA-directed DNA polymerase activity IEP Enrichment
MF GO:0003916 DNA topoisomerase activity IEP Enrichment
MF GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEP Enrichment
MF GO:0003919 FMN adenylyltransferase activity IEP Enrichment
MF GO:0004107 chorismate synthase activity IEP Enrichment
MF GO:0004611 phosphoenolpyruvate carboxykinase activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004814 arginine-tRNA ligase activity IEP Enrichment
MF GO:0004820 glycine-tRNA ligase activity IEP Enrichment
MF GO:0004832 valine-tRNA ligase activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
CC GO:0005737 cytoplasm IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006188 IMP biosynthetic process IEP Enrichment
BP GO:0006189 'de novo' IMP biosynthetic process IEP Enrichment
BP GO:0006259 DNA metabolic process IEP Enrichment
BP GO:0006265 DNA topological change IEP Enrichment
BP GO:0006364 rRNA processing IEP Enrichment
BP GO:0006396 RNA processing IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006420 arginyl-tRNA aminoacylation IEP Enrichment
BP GO:0006426 glycyl-tRNA aminoacylation IEP Enrichment
BP GO:0006438 valyl-tRNA aminoacylation IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
BP GO:0006720 isoprenoid metabolic process IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006753 nucleoside phosphate metabolic process IEP Enrichment
BP GO:0006793 phosphorus metabolic process IEP Enrichment
BP GO:0006796 phosphate-containing compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006996 organelle organization IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
BP GO:0008150 biological_process IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
MF GO:0008171 O-methyltransferase activity IEP Enrichment
MF GO:0008173 RNA methyltransferase activity IEP Enrichment
MF GO:0008175 tRNA methyltransferase activity IEP Enrichment
BP GO:0008299 isoprenoid biosynthetic process IEP Enrichment
MF GO:0008531 riboflavin kinase activity IEP Enrichment
MF GO:0008705 methionine synthase activity IEP Enrichment
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Enrichment
MF GO:0008964 phosphoenolpyruvate carboxylase activity IEP Enrichment
MF GO:0009020 tRNA (guanosine-2'-O-)-methyltransferase activity IEP Enrichment
BP GO:0009058 biosynthetic process IEP Enrichment
BP GO:0009086 methionine biosynthetic process IEP Enrichment
BP GO:0009143 nucleoside triphosphate catabolic process IEP Enrichment
BP GO:0009403 toxin biosynthetic process IEP Enrichment
BP GO:0009404 toxin metabolic process IEP Enrichment
BP GO:0009987 cellular process IEP Enrichment
BP GO:0015969 guanosine tetraphosphate metabolic process IEP Enrichment
BP GO:0015977 carbon fixation IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
BP GO:0016072 rRNA metabolic process IEP Enrichment
MF GO:0016423 tRNA (guanine) methyltransferase activity IEP Enrichment
MF GO:0016740 transferase activity IEP Enrichment
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Enrichment
MF GO:0016779 nucleotidyltransferase activity IEP Enrichment
MF GO:0016838 carbon-oxygen lyase activity, acting on phosphates IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0016887 ATPase IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
BP GO:0019748 secondary metabolic process IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
BP GO:0031167 rRNA methylation IEP Enrichment
MF GO:0031419 cobalamin binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
BP GO:0034035 purine ribonucleoside bisphosphate metabolic process IEP Enrichment
MF GO:0034061 DNA polymerase activity IEP Enrichment
BP GO:0034470 ncRNA processing IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
MF GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0043170 macromolecule metabolic process IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044260 cellular macromolecule metabolic process IEP Enrichment
BP GO:0044281 small molecule metabolic process IEP Enrichment
BP GO:0044283 small molecule biosynthetic process IEP Enrichment
BP GO:0044550 secondary metabolite biosynthetic process IEP Enrichment
BP GO:0046040 IMP metabolic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
MF GO:0050660 flavin adenine dinucleotide binding IEP Enrichment
BP GO:0051276 chromosome organization IEP Enrichment
MF GO:0052689 carboxylic ester hydrolase activity IEP Enrichment
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Enrichment
MF GO:0062105 RNA 2'-O-methyltransferase activity IEP Enrichment
BP GO:0070475 rRNA base methylation IEP Enrichment
BP GO:0071103 DNA conformation change IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0106050 tRNA 2'-O-methyltransferase activity IEP Enrichment
MF GO:0140097 catalytic activity, acting on DNA IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR020630 THF_DH/CycHdrlase_cat_dom 5 121
IPR020631 THF_DH/CycHdrlase_NAD-bd_dom 124 279
No external refs found!