CRO51482 (purH)

Aliases : purH

Description : Bifunctional purine biosynthesis protein PurH [Ensembl]. MGS-like domain, AICARFT/IMPCHase bienzyme [Interproscan].

Gene families : OG_02_0000542 (OrthoFinder) Phylogenetic Tree(s): OG0000542_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CRO51482
Cluster	HCCA: Cluster_51

Target	Alias	Description	ECC score	Gene Family Method
AAC76980	purH, b4006	IMP cyclohydrolase and...	0.03	OrthoFinder
AAK98855	spr0051, purH	Phosphoribosylaminoimidazolecarboxamide...	0.05	OrthoFinder
AAL23004	STM4176, purH	phosphoribosylaminoimidazolecarboxamide...	0.03	OrthoFinder
AEA94177	purH, OG1RF_11490	bifunctional purine biosynthesis protein PurH [Ensembl]....	0.03	OrthoFinder
AGT26493	N559_4909	phosphoribosylaminoimidazolecarboxamide...	0.03	OrthoFinder
AHY40167	purH, CJ8421_04720	bifunctional phosphoribosylaminoimidazolecarboxamide...	0.04	OrthoFinder
AKI49759	purH, L2625_01901	phosphoribosylaminoimidazolecarboxamide...	0.03	OrthoFinder
CCL18088	purH, BN171_210024	Bifunctional purine biosynthesis protein purH (Includes:...	0.04	OrthoFinder
CPC40781	purH, ERS093114_00351	IMP cyclohydrolase [Ensembl]. MGS-like domain,...	0.03	OrthoFinder
EDJ91669	purH, CGSHi22421_07938	bifunctional phosphoribosylaminoimidazolecarboxamide...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003937	IMP cyclohydrolase activity	IEA	Interproscan
MF	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006164	purine nucleotide biosynthetic process	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	None	Extended
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
MF	GO:0019238	cyclohydrolase activity	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0072522	purine-containing compound biosynthetic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003735	structural constituent of ribosome	IEP	Enrichment
MF	GO:0003746	translation elongation factor activity	IEP	Enrichment
MF	GO:0003747	translation release factor activity	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004470	malic enzyme activity	IEP	Enrichment
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEP	Enrichment
MF	GO:0004637	phosphoribosylamine-glycine ligase activity	IEP	Enrichment
MF	GO:0004652	polynucleotide adenylyltransferase activity	IEP	Enrichment
MF	GO:0004751	ribose-5-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004810	tRNA adenylyltransferase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005198	structural molecule activity	IEP	Enrichment
MF	GO:0005216	ion channel activity	IEP	Enrichment
MF	GO:0005261	cation channel activity	IEP	Enrichment
MF	GO:0005488	binding	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005575	cellular_component	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
CC	GO:0005840	ribosome	IEP	Enrichment
BP	GO:0006144	purine nucleobase metabolic process	IEP	Enrichment
BP	GO:0006177	GMP biosynthetic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Enrichment
BP	GO:0006364	rRNA processing	IEP	Enrichment
BP	GO:0006396	RNA processing	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006412	translation	IEP	Enrichment
BP	GO:0006415	translational termination	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006457	protein folding	IEP	Enrichment
BP	GO:0006518	peptide metabolic process	IEP	Enrichment
BP	GO:0006643	membrane lipid metabolic process	IEP	Enrichment
BP	GO:0006644	phospholipid metabolic process	IEP	Enrichment
BP	GO:0006664	glycolipid metabolic process	IEP	Enrichment
BP	GO:0006814	sodium ion transport	IEP	Enrichment
BP	GO:0008033	tRNA processing	IEP	Enrichment
MF	GO:0008079	translation termination factor activity	IEP	Enrichment
MF	GO:0008135	translation factor activity, RNA binding	IEP	Enrichment
MF	GO:0008173	RNA methyltransferase activity	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
BP	GO:0008360	regulation of cell shape	IEP	Enrichment
BP	GO:0008616	queuosine biosynthetic process	IEP	Enrichment
BP	GO:0008654	phospholipid biosynthetic process	IEP	Enrichment
MF	GO:0008915	lipid-A-disaccharide synthase activity	IEP	Enrichment
BP	GO:0009052	pentose-phosphate shunt, non-oxidative branch	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009112	nucleobase metabolic process	IEP	Enrichment
BP	GO:0009113	purine nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0009119	ribonucleoside metabolic process	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009163	nucleoside biosynthetic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009245	lipid A biosynthetic process	IEP	Enrichment
BP	GO:0009247	glycolipid biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009311	oligosaccharide metabolic process	IEP	Enrichment
BP	GO:0009312	oligosaccharide biosynthetic process	IEP	Enrichment
MF	GO:0015175	neutral amino acid transmembrane transporter activity	IEP	Enrichment
MF	GO:0015252	proton channel activity	IEP	Enrichment
MF	GO:0015293	symporter activity	IEP	Enrichment
MF	GO:0015655	alanine:sodium symporter activity	IEP	Enrichment
BP	GO:0015804	neutral amino acid transport	IEP	Enrichment
BP	GO:0016051	carbohydrate biosynthetic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
BP	GO:0016072	rRNA metabolic process	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
MF	GO:0019843	rRNA binding	IEP	Enrichment
BP	GO:0022411	cellular component disassembly	IEP	Enrichment
BP	GO:0022603	regulation of anatomical structure morphogenesis	IEP	Enrichment
BP	GO:0022604	regulation of cell morphogenesis	IEP	Enrichment
MF	GO:0022858	alanine transmembrane transporter activity	IEP	Enrichment
BP	GO:0031554	regulation of DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0032328	alanine transport	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
BP	GO:0032984	protein-containing complex disassembly	IEP	Enrichment
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043043	peptide biosynthetic process	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043228	non-membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Enrichment
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043603	cellular amide metabolic process	IEP	Enrichment
BP	GO:0043604	amide biosynthetic process	IEP	Enrichment
BP	GO:0043624	cellular protein complex disassembly	IEP	Enrichment
BP	GO:0043933	protein-containing complex subunit organization	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0044267	cellular protein metabolic process	IEP	Enrichment
MF	GO:0045182	translation regulator activity	IEP	Enrichment
CC	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Enrichment
BP	GO:0046037	GMP metabolic process	IEP	Enrichment
BP	GO:0046112	nucleobase biosynthetic process	IEP	Enrichment
BP	GO:0046116	queuosine metabolic process	IEP	Enrichment
BP	GO:0046148	pigment biosynthetic process	IEP	Enrichment
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Enrichment
BP	GO:0046467	membrane lipid biosynthetic process	IEP	Enrichment
BP	GO:0046493	lipid A metabolic process	IEP	Enrichment
MF	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0050793	regulation of developmental process	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
MF	GO:0051536	iron-sulfur cluster binding	IEP	Enrichment
MF	GO:0051540	metal cluster binding	IEP	Enrichment
MF	GO:0070566	adenylyltransferase activity	IEP	Enrichment
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
CC	GO:0110165	cellular anatomical entity	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901269	lipooligosaccharide metabolic process	IEP	Enrichment
BP	GO:1901271	lipooligosaccharide biosynthetic process	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Enrichment
BP	GO:1903509	liposaccharide metabolic process	IEP	Enrichment
MF	GO:1990817	RNA adenylyltransferase activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR011607	MGS-like_dom	22	135
IPR002695	PurH-like	140	466

External Links

Locus_tag	PAERUG_E11_London_26_VIM_2_06_13_02647

CRO51482 (purH)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation