CRO74499 (rpoA)

Aliases : rpoA

Description : DNA-directed RNA polymerase subunit alpha [Ensembl]. Bacterial RNA polymerase, RNA polymerase Rpb3/RpoA insert domain, RNA polymerase Rpb3/Rpb11 dimerisation domain [Interproscan].

Gene families : OG_02_0000391 (OrthoFinder) Phylogenetic Tree(s): OG0000391_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CRO74499
Cluster	HCCA: Cluster_22

Target	Alias	Description	ECC score	Gene Family Method
AAC76320	rpoA, b3295	RNA polymerase, alpha subunit [Ensembl]. Bacterial RNA...	0.34	OrthoFinder
AAK99019	spr0215, rpoA	RNA polymerase alpha subunit [Ensembl]. Bacterial RNA...	0.2	OrthoFinder
AAL22278	STM3415, rpoA	RNA polymerase, alpha subunit [Ensembl]. Bacterial RNA...	0.35	OrthoFinder
ADK86748	rpoA, MPNE_0220	DNA-directed RNA polymerase, alpha subunit [Ensembl]....	0.15	OrthoFinder
AEA92864	rpoA, OG1RF_10177	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.13	OrthoFinder
AGT22265	N559_0457	DNA-directed RNA polymerase subunit alpha [Ensembl]. RNA...	0.24	OrthoFinder
AHY40768	CJ8421_07980	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.18	OrthoFinder
AKI50541	rpoA, L2625_02751	DNA-directed RNA polymerase, alpha subunit [Ensembl]....	0.21	OrthoFinder
AKP15146	rpoA, WX61_01092	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.13	OrthoFinder
CBI65743	rpoA, HPB8_186	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.18	OrthoFinder
CCG27405	No alias	DNA-directed RNA polymerase alpha subunit [Ensembl]....	0.11	OrthoFinder
CCL20591	rpoA, BN171_70031	DNA-directed RNA polymerase subunit alpha [Ensembl]. RNA...	0.21	OrthoFinder
CCP46279	rpoA, Rv3457c	Probable DNA-directed RNA polymerase (alpha chain) RpoA...	0.19	OrthoFinder
CPD14384	rpoA, ERS093114_02148	DNA-directed RNA polymerase alpha subunit [Ensembl]....	0.27	OrthoFinder
EDJ91381	CGSHi22421_04738	DNA-directed RNA polymerase subunit alpha [Ensembl]....	0.27	OrthoFinder
KNA54997	VCV51_033180	DNA-directed RNA polymerase [Ensembl]. Bacterial RNA...	0.26	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006351	transcription, DNA-templated	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0032774	RNA biosynthetic process	None	Extended
MF	GO:0034062	5'-3' RNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046983	protein dimerization activity	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:0097659	nucleic acid-templated transcription	None	Extended
MF	GO:0097747	RNA polymerase activity	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003735	structural constituent of ribosome	IEP	Enrichment
MF	GO:0003746	translation elongation factor activity	IEP	Enrichment
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004470	malic enzyme activity	IEP	Enrichment
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEP	Enrichment
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEP	Enrichment
MF	GO:0004612	phosphoenolpyruvate carboxykinase (ATP) activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005198	structural molecule activity	IEP	Enrichment
MF	GO:0005216	ion channel activity	IEP	Enrichment
MF	GO:0005261	cation channel activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005575	cellular_component	IEP	Enrichment
CC	GO:0005840	ribosome	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006177	GMP biosynthetic process	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006412	translation	IEP	Enrichment
BP	GO:0006414	translational elongation	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006518	peptide metabolic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006754	ATP biosynthetic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0006811	ion transport	IEP	Enrichment
BP	GO:0006812	cation transport	IEP	Enrichment
MF	GO:0008097	5S rRNA binding	IEP	Enrichment
MF	GO:0008135	translation factor activity, RNA binding	IEP	Enrichment
MF	GO:0008324	cation transmembrane transporter activity	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Enrichment
MF	GO:0015078	proton transmembrane transporter activity	IEP	Enrichment
MF	GO:0015252	proton channel activity	IEP	Enrichment
MF	GO:0015267	channel activity	IEP	Enrichment
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Enrichment
BP	GO:0015969	guanosine tetraphosphate metabolic process	IEP	Enrichment
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Enrichment
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
MF	GO:0019843	rRNA binding	IEP	Enrichment
MF	GO:0022803	passive transmembrane transporter activity	IEP	Enrichment
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
BP	GO:0031554	regulation of DNA-templated transcription, termination	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
CC	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	IEP	Enrichment
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Enrichment
BP	GO:0033865	nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034220	ion transmembrane transport	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043043	peptide biosynthetic process	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
CC	GO:0043226	organelle	IEP	Enrichment
CC	GO:0043228	non-membrane-bounded organelle	IEP	Enrichment
CC	GO:0043229	intracellular organelle	IEP	Enrichment
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Enrichment
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043603	cellular amide metabolic process	IEP	Enrichment
BP	GO:0043604	amide biosynthetic process	IEP	Enrichment
BP	GO:0044267	cellular protein metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
MF	GO:0045182	translation regulator activity	IEP	Enrichment
CC	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Enrichment
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046037	GMP metabolic process	IEP	Enrichment
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Enrichment
MF	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
BP	GO:0098655	cation transmembrane transport	IEP	Enrichment
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Enrichment
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Enrichment
CC	GO:0098796	membrane protein complex	IEP	Enrichment
CC	GO:0110165	cellular anatomical entity	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1902600	proton transmembrane transport	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR011262	DNA-dir_RNA_pol_insert	64	155
IPR011263	DNA-dir_RNA_pol_RpoA/D/Rpb3	29	227
IPR011260	RNAP_asu_C	243	307

External Links

Locus_tag	PAERUG_E11_London_26_VIM_2_06_13_03323

CRO74499 (rpoA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation