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  5. CRP05042

CRP05042 (purK)


Aliases : purK

Description : N5-carboxyaminoimidazole ribonucleotide synthase [Ensembl]. ATP-grasp domain, Phosphoribosylaminoimidazole carboxylase C-terminal domain [Interproscan].


Gene families : OG_02_0000599 (OrthoFinder) Phylogenetic Tree(s): OG0000599_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CRP05042
Cluster HCCA: Cluster_40

Target Alias Description ECC score Gene Family Method Actions
AAC73624 purK, b0522 N5-carboxyaminoimidazole ribonucleotide synthase... 0.05 OrthoFinder
AAK98858 spr0054, purK Phosphoribosyl glucinamide formyltransferase [Ensembl].... 0.05 OrthoFinder
AAL19487 STM0533, purK phosphoribosylaminoimidazole carboxylase = AIR... 0.06 OrthoFinder
AEA94185 purK, OG1RF_11498 phosphoribosylaminoimidazole carboxylase ATPase subunit... 0.03 OrthoFinder
AKI49768 purK, L2625_01910 phosphoribosylaminoimidazole carboxylase, ATPase subunit... 0.07 OrthoFinder
AKP16083 purK, WX61_02057 N5-carboxyaminoimidazole ribonucleotide synthase... 0.05 OrthoFinder
CPC41036 purK, ERS093114_00359 Phosphoribosylaminoimidazole carboxylase ATPase subunit... 0.06 OrthoFinder
EDJ90912 CGSHi22421_03648 phosphoribosylaminoimidazole carboxylase [Ensembl]. 0.02 OrthoFinder
KNA53679 VCV51_030034 phosphoribosylaminoimidazole carboxylase [Ensembl].... 0.07 OrthoFinder

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0000049 tRNA binding IEP Enrichment
BP GO:0000105 histidine biosynthetic process IEP Enrichment
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0003674 molecular_function IEP Enrichment
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003746 translation elongation factor activity IEP Enrichment
MF GO:0003824 catalytic activity IEP Enrichment
MF GO:0003896 DNA primase activity IEP Enrichment
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Enrichment
MF GO:0003909 DNA ligase activity IEP Enrichment
MF GO:0003911 DNA ligase (NAD+) activity IEP Enrichment
MF GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEP Enrichment
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Enrichment
MF GO:0003937 IMP cyclohydrolase activity IEP Enrichment
MF GO:0004019 adenylosuccinate synthase activity IEP Enrichment
MF GO:0004399 histidinol dehydrogenase activity IEP Enrichment
MF GO:0004521 endoribonuclease activity IEP Enrichment
MF GO:0004525 ribonuclease III activity IEP Enrichment
MF GO:0004540 ribonuclease activity IEP Enrichment
MF GO:0004590 orotidine-5'-phosphate decarboxylase activity IEP Enrichment
MF GO:0004637 phosphoribosylamine-glycine ligase activity IEP Enrichment
MF GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity IEP Enrichment
MF GO:0004665 prephenate dehydrogenase (NADP+) activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004814 arginine-tRNA ligase activity IEP Enrichment
MF GO:0004820 glycine-tRNA ligase activity IEP Enrichment
MF GO:0004826 phenylalanine-tRNA ligase activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
CC GO:0005737 cytoplasm IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006144 purine nucleobase metabolic process IEP Enrichment
BP GO:0006163 purine nucleotide metabolic process IEP Enrichment
BP GO:0006164 purine nucleotide biosynthetic process IEP Enrichment
BP GO:0006177 GMP biosynthetic process IEP Enrichment
BP GO:0006188 IMP biosynthetic process IEP Enrichment
BP GO:0006189 'de novo' IMP biosynthetic process IEP Enrichment
BP GO:0006206 pyrimidine nucleobase metabolic process IEP Enrichment
BP GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process IEP Enrichment
BP GO:0006259 DNA metabolic process IEP Enrichment
BP GO:0006260 DNA replication IEP Enrichment
BP GO:0006269 DNA replication, synthesis of RNA primer IEP Enrichment
BP GO:0006281 DNA repair IEP Enrichment
BP GO:0006351 transcription, DNA-templated IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006414 translational elongation IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006420 arginyl-tRNA aminoacylation IEP Enrichment
BP GO:0006426 glycyl-tRNA aminoacylation IEP Enrichment
BP GO:0006432 phenylalanyl-tRNA aminoacylation IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
BP GO:0006534 cysteine metabolic process IEP Enrichment
BP GO:0006547 histidine metabolic process IEP Enrichment
BP GO:0006570 tyrosine metabolic process IEP Enrichment
BP GO:0006571 tyrosine biosynthetic process IEP Enrichment
BP GO:0006643 membrane lipid metabolic process IEP Enrichment
BP GO:0006664 glycolipid metabolic process IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006753 nucleoside phosphate metabolic process IEP Enrichment
BP GO:0006779 porphyrin-containing compound biosynthetic process IEP Enrichment
BP GO:0006793 phosphorus metabolic process IEP Enrichment
BP GO:0006796 phosphate-containing compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006950 response to stress IEP Enrichment
BP GO:0006974 cellular response to DNA damage stimulus IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
BP GO:0008150 biological_process IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
MF GO:0008168 methyltransferase activity IEP Enrichment
MF GO:0008194 UDP-glycosyltransferase activity IEP Enrichment
BP GO:0008360 regulation of cell shape IEP Enrichment
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEP Enrichment
BP GO:0008652 cellular amino acid biosynthetic process IEP Enrichment
MF GO:0008915 lipid-A-disaccharide synthase activity IEP Enrichment
MF GO:0008977 prephenate dehydrogenase (NAD+) activity IEP Enrichment
BP GO:0009058 biosynthetic process IEP Enrichment
BP GO:0009059 macromolecule biosynthetic process IEP Enrichment
BP GO:0009092 homoserine metabolic process IEP Enrichment
BP GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway IEP Enrichment
BP GO:0009112 nucleobase metabolic process IEP Enrichment
BP GO:0009113 purine nucleobase biosynthetic process IEP Enrichment
BP GO:0009117 nucleotide metabolic process IEP Enrichment
BP GO:0009123 nucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009150 purine ribonucleotide metabolic process IEP Enrichment
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Enrichment
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009165 nucleotide biosynthetic process IEP Enrichment
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Enrichment
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Enrichment
BP GO:0009245 lipid A biosynthetic process IEP Enrichment
BP GO:0009247 glycolipid biosynthetic process IEP Enrichment
BP GO:0009259 ribonucleotide metabolic process IEP Enrichment
BP GO:0009260 ribonucleotide biosynthetic process IEP Enrichment
BP GO:0009312 oligosaccharide biosynthetic process IEP Enrichment
BP GO:0009987 cellular process IEP Enrichment
BP GO:0016053 organic acid biosynthetic process IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
MF GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IEP Enrichment
MF GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor IEP Enrichment
MF GO:0016740 transferase activity IEP Enrichment
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Enrichment
MF GO:0016757 glycosyltransferase activity IEP Enrichment
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Enrichment
MF GO:0016779 nucleotidyltransferase activity IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0016877 ligase activity, forming carbon-sulfur bonds IEP Enrichment
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Enrichment
MF GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters IEP Enrichment
MF GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
BP GO:0018130 heterocycle biosynthetic process IEP Enrichment
MF GO:0019001 guanyl nucleotide binding IEP Enrichment
MF GO:0019238 cyclohydrolase activity IEP Enrichment
BP GO:0019346 transsulfuration IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0019637 organophosphate metabolic process IEP Enrichment
BP GO:0019693 ribose phosphate metabolic process IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
BP GO:0019856 pyrimidine nucleobase biosynthetic process IEP Enrichment
BP GO:0022603 regulation of anatomical structure morphogenesis IEP Enrichment
BP GO:0022604 regulation of cell morphogenesis IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0032296 double-stranded RNA-specific ribonuclease activity IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
MF GO:0032561 guanyl ribonucleotide binding IEP Enrichment
BP GO:0032774 RNA biosynthetic process IEP Enrichment
BP GO:0033013 tetrapyrrole metabolic process IEP Enrichment
BP GO:0033014 tetrapyrrole biosynthetic process IEP Enrichment
BP GO:0033554 cellular response to stress IEP Enrichment
MF GO:0034062 5'-3' RNA polymerase activity IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034645 cellular macromolecule biosynthetic process IEP Enrichment
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
MF GO:0043138 3'-5' DNA helicase activity IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0043170 macromolecule metabolic process IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044260 cellular macromolecule metabolic process IEP Enrichment
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Enrichment
BP GO:0044281 small molecule metabolic process IEP Enrichment
BP GO:0044283 small molecule biosynthetic process IEP Enrichment
BP GO:0046037 GMP metabolic process IEP Enrichment
BP GO:0046040 IMP metabolic process IEP Enrichment
BP GO:0046112 nucleobase biosynthetic process IEP Enrichment
BP GO:0046148 pigment biosynthetic process IEP Enrichment
BP GO:0046390 ribose phosphate biosynthetic process IEP Enrichment
BP GO:0046394 carboxylic acid biosynthetic process IEP Enrichment
BP GO:0046467 membrane lipid biosynthetic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
BP GO:0046493 lipid A metabolic process IEP Enrichment
BP GO:0050667 homocysteine metabolic process IEP Enrichment
BP GO:0050793 regulation of developmental process IEP Enrichment
MF GO:0051287 NAD binding IEP Enrichment
BP GO:0051716 cellular response to stimulus IEP Enrichment
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Enrichment
MF GO:0070402 NADPH binding IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0072521 purine-containing compound metabolic process IEP Enrichment
BP GO:0072522 purine-containing compound biosynthetic process IEP Enrichment
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Enrichment
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
BP GO:0090407 organophosphate biosynthetic process IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
BP GO:0097659 nucleic acid-templated transcription IEP Enrichment
MF GO:0097747 RNA polymerase activity IEP Enrichment
MF GO:0140097 catalytic activity, acting on DNA IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
BP GO:1901135 carbohydrate derivative metabolic process IEP Enrichment
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901269 lipooligosaccharide metabolic process IEP Enrichment
BP GO:1901271 lipooligosaccharide biosynthetic process IEP Enrichment
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
BP GO:1901362 organic cyclic compound biosynthetic process IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
BP GO:1901566 organonitrogen compound biosynthetic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR003135 ATP-grasp_carboxylate-amine 106 272
IPR040686 PurK_C 298 350
Locus_tag PAERUG_E11_London_26_VIM_2_06_13_04233