CRP56454 (pykA)

Aliases : pykA

Description : Pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].

Gene families : OG_02_0000218 (OrthoFinder) Phylogenetic Tree(s): OG0000218_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CRP56454
Cluster	HCCA: Cluster_47

Target	Alias	Description	ECC score	Gene Family Method
AAC74746	pykF, b1676	pyruvate kinase I [Ensembl]. Pyruvate kinase [Interproscan].	0.02	OrthoFinder
AAC74924	pykA, b1854	pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.03	OrthoFinder
AAK99601	spr0797, pykF	Pyruvate kinase I; fructose-stimulated [Ensembl]....	0.03	OrthoFinder
AAL20302	STM1378, pykF	pyruvate kinase I [Ensembl]. Pyruvate kinase [Interproscan].	0.03	OrthoFinder
AAL20804	STM1888, pykA	pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.04	OrthoFinder
AGT23623	N559_1890	pyruvate kinase [Ensembl]. barrel domain, alpha/beta...	0.03	OrthoFinder
AKP15076	pykA, WX61_01018	Pyruvate kinase II [Ensembl]. Pyruvate kinase [Interproscan].	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004743	pyruvate kinase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0005975	carbohydrate metabolic process	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006090	pyruvate metabolic process	None	Extended
BP	GO:0006091	generation of precursor metabolites and energy	None	Extended
BP	GO:0006096	glycolytic process	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006165	nucleoside diphosphate phosphorylation	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006757	ATP generation from ADP	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009132	nucleoside diphosphate metabolic process	None	Extended
BP	GO:0009135	purine nucleoside diphosphate metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	None	Extended
BP	GO:0009185	ribonucleoside diphosphate metabolic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016052	carbohydrate catabolic process	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030955	potassium ion binding	IEA	Interproscan
MF	GO:0031420	alkali metal ion binding	None	Extended
BP	GO:0032787	monocarboxylic acid metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046031	ADP metabolic process	None	Extended
BP	GO:0046034	ATP metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0046939	nucleotide phosphorylation	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0003954	NADH dehydrogenase activity	IEP	Enrichment
MF	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	IEP	Enrichment
MF	GO:0004150	dihydroneopterin aldolase activity	IEP	Enrichment
MF	GO:0004175	endopeptidase activity	IEP	Enrichment
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Enrichment
MF	GO:0004177	aminopeptidase activity	IEP	Enrichment
MF	GO:0004185	serine-type carboxypeptidase activity	IEP	Enrichment
MF	GO:0004222	metalloendopeptidase activity	IEP	Enrichment
MF	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	IEP	Enrichment
MF	GO:0004448	isocitrate dehydrogenase activity	IEP	Enrichment
MF	GO:0004450	isocitrate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004470	malic enzyme activity	IEP	Enrichment
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEP	Enrichment
MF	GO:0004784	superoxide dismutase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0006099	tricarboxylic acid cycle	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006612	protein targeting to membrane	IEP	Enrichment
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006801	superoxide metabolic process	IEP	Enrichment
BP	GO:0008104	protein localization	IEP	Enrichment
MF	GO:0008113	peptide-methionine (S)-S-oxide reductase activity	IEP	Enrichment
MF	GO:0008137	NADH dehydrogenase (ubiquinone) activity	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008236	serine-type peptidase activity	IEP	Enrichment
MF	GO:0008237	metallopeptidase activity	IEP	Enrichment
MF	GO:0008238	exopeptidase activity	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
MF	GO:0008924	malate dehydrogenase (quinone) activity	IEP	Enrichment
MF	GO:0009002	serine-type D-Ala-D-Ala carboxypeptidase activity	IEP	Enrichment
MF	GO:0009055	electron transfer activity	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0015031	protein transport	IEP	Enrichment
BP	GO:0015969	guanosine tetraphosphate metabolic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016151	nickel cation binding	IEP	Enrichment
MF	GO:0016209	antioxidant activity	IEP	Enrichment
MF	GO:0016491	oxidoreductase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016615	malate dehydrogenase activity	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	IEP	Enrichment
MF	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEP	Enrichment
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	IEP	Enrichment
BP	GO:0017038	protein import	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
MF	GO:0017171	serine hydrolase activity	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019627	urea metabolic process	IEP	Enrichment
BP	GO:0019725	cellular homeostasis	IEP	Enrichment
MF	GO:0020037	heme binding	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
BP	GO:0033036	macromolecule localization	IEP	Enrichment
BP	GO:0033365	protein localization to organelle	IEP	Enrichment
BP	GO:0033865	nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	IEP	Enrichment
BP	GO:0034613	cellular protein localization	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042592	homeostatic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0043419	urea catabolic process	IEP	Enrichment
BP	GO:0043605	cellular amide catabolic process	IEP	Enrichment
BP	GO:0045047	protein targeting to ER	IEP	Enrichment
BP	GO:0045184	establishment of protein localization	IEP	Enrichment
BP	GO:0046168	glycerol-3-phosphate catabolic process	IEP	Enrichment
MF	GO:0046906	tetrapyrrole binding	IEP	Enrichment
MF	GO:0046914	transition metal ion binding	IEP	Enrichment
MF	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0048038	quinone binding	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
MF	GO:0050136	NADH dehydrogenase (quinone) activity	IEP	Enrichment
MF	GO:0051287	NAD binding	IEP	Enrichment
BP	GO:0051668	localization within membrane	IEP	Enrichment
BP	GO:0052646	alditol phosphate metabolic process	IEP	Enrichment
BP	GO:0055114	obsolete oxidation-reduction process	IEP	Enrichment
BP	GO:0065008	regulation of biological quality	IEP	Enrichment
BP	GO:0070727	cellular macromolecule localization	IEP	Enrichment
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0071941	nitrogen cycle metabolic process	IEP	Enrichment
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Enrichment
BP	GO:0072594	establishment of protein localization to organelle	IEP	Enrichment
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072657	protein localization to membrane	IEP	Enrichment
BP	GO:0090150	establishment of protein localization to membrane	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
CC	GO:1990904	ribonucleoprotein complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR015793	Pyrv_Knase_brl	4	342
IPR015795	Pyrv_Knase_C	361	476

External Links

Locus_tag	PAERUG_E11_London_26_VIM_2_06_13_05769

CRP56454 (pykA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation