AAC73305 (proS, b0194)

Aliases : proS, b0194

Description : prolyl-tRNA synthetase [Ensembl]. Anticodon binding domain, Aminoacyl-tRNA editing domain, tRNA synthetase class II core domain (G [Interproscan].

Gene families : OG_02_0000443 (OrthoFinder) Phylogenetic Tree(s): OG0000443_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC73305
Cluster	HCCA: Cluster_37

Target	Alias	Description	ECC score	Gene Family Method
AAL19205	STM0242, proS	proline tRNA synthetase [Ensembl]. Anticodon binding...	0.21	OrthoFinder
AEA94505	proS, OG1RF_11818	proline--tRNA ligase [Ensembl]. Anticodon binding...	0.08	OrthoFinder
AGT25831	N559_4206	prolyl-tRNA synthetase [Ensembl]. tRNA synthetase class...	0.13	OrthoFinder
AKI49315	proS, L2625_01409	prolyl-tRNA synthetase [Ensembl]. Aminoacyl-tRNA...	0.06	OrthoFinder
AKP14223	proS, WX61_00134	Proline--tRNA ligase [Ensembl]. Anticodon binding...	0.1	OrthoFinder
CBI66882	proS, HPB8_1325	prolyl-tRNA synthetase [Ensembl]. Anticodon binding...	0.04	OrthoFinder
CPC35118	proS, ERS093114_00161	Prolyl-tRNA synthetase [Ensembl]. Anticodon binding...	0.06	OrthoFinder
CRN72909	proS	Proline--tRNA ligase [Ensembl]. Anticodon binding...	0.09	OrthoFinder
KNA56974	VCV51_030590	prolyl-tRNA synthetase [Ensembl]. Anticodon binding...	0.1	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0003989	acetyl-CoA carboxylase activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0004129	cytochrome-c oxidase activity	IEP	Enrichment
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0004592	pantoate-beta-alanine ligase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005261	cation channel activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006189	'de novo' IMP biosynthetic process	IEP	Enrichment
BP	GO:0006323	DNA packaging	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006644	phospholipid metabolic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006754	ATP biosynthetic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0006811	ion transport	IEP	Enrichment
BP	GO:0006812	cation transport	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
BP	GO:0007059	chromosome segregation	IEP	Enrichment
MF	GO:0008324	cation transmembrane transporter activity	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
BP	GO:0008654	phospholipid biosynthetic process	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009116	nucleoside metabolic process	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Enrichment
CC	GO:0009295	nucleoid	IEP	Enrichment
CC	GO:0009317	acetyl-CoA carboxylase complex	IEP	Enrichment
MF	GO:0015002	obsolete heme-copper terminal oxidase activity	IEP	Enrichment
MF	GO:0015075	ion transmembrane transporter activity	IEP	Enrichment
MF	GO:0015078	proton transmembrane transporter activity	IEP	Enrichment
MF	GO:0015252	proton channel activity	IEP	Enrichment
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Enrichment
BP	GO:0015939	pantothenate metabolic process	IEP	Enrichment
BP	GO:0015940	pantothenate biosynthetic process	IEP	Enrichment
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Enrichment
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
MF	GO:0016421	CoA carboxylase activity	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	IEP	Enrichment
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Enrichment
MF	GO:0016885	ligase activity, forming carbon-carbon bonds	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Enrichment
BP	GO:0030261	chromosome condensation	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Enrichment
CC	GO:0032991	protein-containing complex	IEP	Enrichment
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Enrichment
BP	GO:0034220	ion transmembrane transport	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
CC	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Enrichment
CC	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Enrichment
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Enrichment
MF	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
BP	GO:0070206	protein trimerization	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0072330	monocarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
BP	GO:0098655	cation transmembrane transport	IEP	Enrichment
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Enrichment
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Enrichment
CC	GO:0098796	membrane protein complex	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901657	glycosyl compound metabolic process	IEP	Enrichment
BP	GO:1902600	proton transmembrane transport	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR002314	aa-tRNA-synt_IIb	95	459
IPR004154	Anticodon-bd	475	568
IPR007214	YbaK/aa-tRNA-synth-assoc-dom	257	376

External Links

UniProtKB	P16659

AAC73305 (proS, b0194)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation