AAC75291 (gyrA, b2231)

Aliases : gyrA, b2231

Description : DNA gyrase (type II topoisomerase), subunit A [Ensembl]. DNA gyrase/topoisomerase IV, DNA gyrase C-terminal domain [Interproscan].

Gene families : OG_02_0000383 (OrthoFinder) Phylogenetic Tree(s): OG0000383_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC75291
Cluster	HCCA: Cluster_41

Target	Alias	Description	ECC score	Gene Family Method
AAK99902	spr1099, gyrA	DNA gyrase subunit A [Ensembl]. DNA gyrase/topoisomerase...	0.03	OrthoFinder
AAL21173	STM2272, gyrA	DNA gyrase, subunit A [Ensembl]. DNA...	0.23	OrthoFinder
ADK86940	gyrA, MPNE_0005	DNA gyrase, A subunit [Ensembl]. DNA...	0.04	OrthoFinder
AGT23360	N559_1614	DNA gyrase subunit A [Ensembl]. DNA gyrase C-terminal...	0.13	OrthoFinder
AHY40234	CJ8421_05100	DNA gyrase subunit A [Ensembl]. DNA gyrase/topoisomerase...	0.03	OrthoFinder
AKI47983	gyrA, L2625_00007	DNA gyrase, A subunit [Ensembl]. DNA topoisomerase, DNA...	0.02	OrthoFinder
AKP14160	gyrA, WX61_00071	DNA gyrase subunit A [Ensembl]. DNA gyrase/topoisomerase...	0.05	OrthoFinder
CBI66459	gyrA, HPB8_902	DNA gyrase, subunit A [Ensembl]. DNA...	0.08	OrthoFinder
CCG27498	No alias	DNA gyrase subunit A [Ensembl]. DNA gyrase/topoisomerase...	0.05	OrthoFinder
CCL16918	gyrA, BN171_10006	DNA gyrase subunit A [Ensembl]. DNA gyrase/topoisomerase...	0.05	OrthoFinder
CRP64092	gyrA	DNA gyrase subunit A [Ensembl]. DNA gyrase/topoisomerase...	0.06	OrthoFinder
EDJ91023	CGSHi22421_02836	DNA gyrase subunit A [Ensembl]. DNA gyrase/topoisomerase...	0.08	OrthoFinder
KNA55992	VCV51_030910	DNA gyrase subunit A [Ensembl]. DNA gyrase/topoisomerase...	0.03	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	ATPase, acting on DNA	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003896	DNA primase activity	IEP	Enrichment
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Enrichment
MF	GO:0003924	GTPase activity	IEP	Enrichment
MF	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	IEP	Enrichment
MF	GO:0004312	fatty acid synthase activity	IEP	Enrichment
MF	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEP	Enrichment
MF	GO:0004427	inorganic diphosphatase activity	IEP	Enrichment
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0004655	porphobilinogen synthase activity	IEP	Enrichment
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Enrichment
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006177	GMP biosynthetic process	IEP	Enrichment
BP	GO:0006188	IMP biosynthetic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Enrichment
BP	GO:0006282	regulation of DNA repair	IEP	Enrichment
BP	GO:0006353	DNA-templated transcription, termination	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006612	protein targeting to membrane	IEP	Enrichment
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Enrichment
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Enrichment
CC	GO:0009349	riboflavin synthase complex	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Enrichment
MF	GO:0016778	diphosphotransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Enrichment
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
MF	GO:0019001	guanyl nucleotide binding	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Enrichment
BP	GO:0032774	RNA biosynthetic process	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
CC	GO:0032991	protein-containing complex	IEP	Enrichment
BP	GO:0033365	protein localization to organelle	IEP	Enrichment
BP	GO:0034613	cellular protein localization	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0043647	inositol phosphate metabolic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0045047	protein targeting to ER	IEP	Enrichment
BP	GO:0046037	GMP metabolic process	IEP	Enrichment
BP	GO:0046040	IMP metabolic process	IEP	Enrichment
BP	GO:0046164	alcohol catabolic process	IEP	Enrichment
BP	GO:0046174	polyol catabolic process	IEP	Enrichment
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Enrichment
BP	GO:0046838	phosphorylated carbohydrate dephosphorylation	IEP	Enrichment
BP	GO:0046855	inositol phosphate dephosphorylation	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
BP	GO:0048583	regulation of response to stimulus	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0051052	regulation of DNA metabolic process	IEP	Enrichment
BP	GO:0051668	localization within membrane	IEP	Enrichment
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Enrichment
BP	GO:0070727	cellular macromolecule localization	IEP	Enrichment
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0071545	inositol phosphate catabolic process	IEP	Enrichment
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0072594	establishment of protein localization to organelle	IEP	Enrichment
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072657	protein localization to membrane	IEP	Enrichment
BP	GO:0080134	regulation of response to stress	IEP	Enrichment
BP	GO:0080135	regulation of cellular response to stress	IEP	Enrichment
BP	GO:0090150	establishment of protein localization to membrane	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901616	organic hydroxy compound catabolic process	IEP	Enrichment
CC	GO:1990904	ribonucleoprotein complex	IEP	Enrichment
BP	GO:2001020	regulation of response to DNA damage stimulus	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR006691	GyrA/parC_rep	646	688
IPR006691	GyrA/parC_rep	744	789
IPR006691	GyrA/parC_rep	692	737
IPR006691	GyrA/parC_rep	793	839
IPR006691	GyrA/parC_rep	538	584
IPR006691	GyrA/parC_rep	588	637
IPR002205	Topo_IIA_A/C	32	506

External Links

UniProtKB	P0AES4

AAC75291 (gyrA, b2231)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation