CBI67148 (clpA, HPB8_1591)

Aliases : clpA, HPB8_1591

Description : ATP-dependent Clp protease ATP-binding subunit ClpA [Ensembl]. C-terminal, AAA lid domain, AAA domain (Cdc48 subfamily), ATPase family associated with various cellular activities (AAA) [Interproscan].

Gene families : OG_02_0000042 (OrthoFinder) Phylogenetic Tree(s): OG0000042_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CBI67148
Cluster	HCCA: Cluster_9

Target	Alias	Description	ECC score	Gene Family Method
AAC75641	clpB, b2592	protein disaggregation chaperone [Ensembl]. C-terminal,...	0.03	OrthoFinder
AGT23103	N559_1341	protein disaggregation chaperone [Ensembl]. D2-small...	0.02	OrthoFinder
AGT26834	N559_5260	ATPase with chaperone activity, ATP-binding subunit...	0.03	OrthoFinder
AHY40314	CJ8421_05510	ATP-dependent Clp protease, ATP-binding subunit ClpA...	0.03	OrthoFinder
CCG26873	ClpE	ATP-dependent Clp protease, ATP-binding subunit ClpE...	0.03	OrthoFinder
CRN66395	clpB_1	Heat shock protein F84.1 [Ensembl]. C-terminal, AAA lid...	0.05	OrthoFinder
EDJ91635	CGSHi22421_07768	hypothetical protein [Ensembl]. C-terminal, AAA lid...	0.03	OrthoFinder
KNA57481	VCV51_030464, ClpB	ATP-dependent chaperone ClpB [Ensembl]. C-terminal, AAA...	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003824	catalytic activity	IEP	Enrichment
MF	GO:0003883	CTP synthase activity	IEP	Enrichment
MF	GO:0004175	endopeptidase activity	IEP	Enrichment
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Enrichment
MF	GO:0004252	serine-type endopeptidase activity	IEP	Enrichment
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Enrichment
MF	GO:0004497	monooxygenase activity	IEP	Enrichment
MF	GO:0004665	prephenate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
CC	GO:0005839	proteasome core complex	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006570	tyrosine metabolic process	IEP	Enrichment
BP	GO:0006571	tyrosine biosynthetic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0008150	biological_process	IEP	Enrichment
BP	GO:0008152	metabolic process	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008236	serine-type peptidase activity	IEP	Enrichment
MF	GO:0008320	protein transmembrane transporter activity	IEP	Enrichment
MF	GO:0008977	prephenate dehydrogenase (NAD+) activity	IEP	Enrichment
BP	GO:0009072	aromatic amino acid family metabolic process	IEP	Enrichment
BP	GO:0009073	aromatic amino acid family biosynthetic process	IEP	Enrichment
BP	GO:0009095	aromatic amino acid family biosynthetic process, prephenate pathway	IEP	Enrichment
BP	GO:0009987	cellular process	IEP	Enrichment
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Enrichment
MF	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	IEP	Enrichment
MF	GO:0016703	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	IEP	Enrichment
MF	GO:0016782	transferase activity, transferring sulphur-containing groups	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
MF	GO:0017171	serine hydrolase activity	IEP	Enrichment
MF	GO:0018580	nitronate monooxygenase activity	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
MF	GO:0022884	macromolecule transmembrane transporter activity	IEP	Enrichment
CC	GO:0032991	protein-containing complex	IEP	Enrichment
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Enrichment
BP	GO:0034220	ion transmembrane transport	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
CC	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
MF	GO:0051536	iron-sulfur cluster binding	IEP	Enrichment
MF	GO:0051540	metal cluster binding	IEP	Enrichment
MF	GO:0070003	threonine-type peptidase activity	IEP	Enrichment
BP	GO:0071704	organic substance metabolic process	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
BP	GO:0098655	cation transmembrane transport	IEP	Enrichment
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Enrichment
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Enrichment
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:0140318	protein transporter activity	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1902600	proton transmembrane transport	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR003959	ATPase_AAA_core	201	303
IPR019489	Clp_ATPase_C	638	716
IPR003959	ATPase_AAA_core	474	632
IPR041546	ClpA/ClpB_AAA_lid	340	434

External Links

UniProtKB	D7FG41

CBI67148 (clpA, HPB8_1591)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation