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  5. AKI49356

AKI49356 (folD, L2625_01453)


Aliases : folD, L2625_01453

Description : methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Ensembl]. Tetrahydrofolate dehydrogenase/cyclohydrolase [Interproscan].


Gene families : OG_02_0000724 (OrthoFinder) Phylogenetic Tree(s): OG0000724_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AKI49356
Cluster HCCA: Cluster_24

Target Alias Description ECC score Gene Family Method Actions
CRP57553 folD Bifunctional protein FolD protein [Ensembl].... 0.03 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA Interproscan
BP GO:0055114 obsolete oxidation-reduction process IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0000155 phosphorelay sensor kinase activity IEP Enrichment
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003690 double-stranded DNA binding IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity IEP Enrichment
MF GO:0004127 cytidylate kinase activity IEP Enrichment
MF GO:0004140 dephospho-CoA kinase activity IEP Enrichment
MF GO:0004386 helicase activity IEP Enrichment
MF GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity IEP Enrichment
MF GO:0004518 nuclease activity IEP Enrichment
MF GO:0004527 exonuclease activity IEP Enrichment
MF GO:0004655 porphobilinogen synthase activity IEP Enrichment
MF GO:0004665 prephenate dehydrogenase (NADP+) activity IEP Enrichment
MF GO:0004672 protein kinase activity IEP Enrichment
MF GO:0004673 protein histidine kinase activity IEP Enrichment
MF GO:0004788 thiamine diphosphokinase activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004814 arginine-tRNA ligase activity IEP Enrichment
MF GO:0004817 cysteine-tRNA ligase activity IEP Enrichment
MF GO:0005436 sodium:phosphate symporter activity IEP Enrichment
MF GO:0005488 binding IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
CC GO:0005737 cytoplasm IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006163 purine nucleotide metabolic process IEP Enrichment
BP GO:0006259 DNA metabolic process IEP Enrichment
BP GO:0006270 DNA replication initiation IEP Enrichment
BP GO:0006275 regulation of DNA replication IEP Enrichment
BP GO:0006281 DNA repair IEP Enrichment
BP GO:0006298 mismatch repair IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006420 arginyl-tRNA aminoacylation IEP Enrichment
BP GO:0006423 cysteinyl-tRNA aminoacylation IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
BP GO:0006570 tyrosine metabolic process IEP Enrichment
BP GO:0006571 tyrosine biosynthetic process IEP Enrichment
BP GO:0006629 lipid metabolic process IEP Enrichment
BP GO:0006720 isoprenoid metabolic process IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006793 phosphorus metabolic process IEP Enrichment
BP GO:0006796 phosphate-containing compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006950 response to stress IEP Enrichment
BP GO:0006974 cellular response to DNA damage stimulus IEP Enrichment
BP GO:0006996 organelle organization IEP Enrichment
BP GO:0007165 signal transduction IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
BP GO:0008150 biological_process IEP Enrichment
BP GO:0008152 metabolic process IEP Enrichment
BP GO:0008299 isoprenoid biosynthetic process IEP Enrichment
BP GO:0008610 lipid biosynthetic process IEP Enrichment
MF GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase activity IEP Enrichment
MF GO:0008897 holo-[acyl-carrier-protein] synthase activity IEP Enrichment
MF GO:0008977 prephenate dehydrogenase (NAD+) activity IEP Enrichment
BP GO:0009058 biosynthetic process IEP Enrichment
BP GO:0009150 purine ribonucleotide metabolic process IEP Enrichment
BP GO:0009229 thiamine diphosphate biosynthetic process IEP Enrichment
BP GO:0009259 ribonucleotide metabolic process IEP Enrichment
CC GO:0009379 Holliday junction helicase complex IEP Enrichment
BP GO:0009987 cellular process IEP Enrichment
MF GO:0015081 sodium ion transmembrane transporter activity IEP Enrichment
MF GO:0015293 symporter activity IEP Enrichment
MF GO:0015294 solute:cation symporter activity IEP Enrichment
MF GO:0015370 solute:sodium symporter activity IEP Enrichment
BP GO:0015936 coenzyme A metabolic process IEP Enrichment
BP GO:0015937 coenzyme A biosynthetic process IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
MF GO:0016301 kinase activity IEP Enrichment
MF GO:0016740 transferase activity IEP Enrichment
MF GO:0016744 transketolase or transaldolase activity IEP Enrichment
MF GO:0016758 hexosyltransferase activity IEP Enrichment
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Enrichment
MF GO:0016775 phosphotransferase activity, nitrogenous group as acceptor IEP Enrichment
MF GO:0016778 diphosphotransferase activity IEP Enrichment
MF GO:0016787 hydrolase activity IEP Enrichment
MF GO:0016788 hydrolase activity, acting on ester bonds IEP Enrichment
MF GO:0016835 carbon-oxygen lyase activity IEP Enrichment
MF GO:0016836 hydro-lyase activity IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0019693 ribose phosphate metabolic process IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
MF GO:0019842 vitamin binding IEP Enrichment
BP GO:0030258 lipid modification IEP Enrichment
BP GO:0030259 lipid glycosylation IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0030975 thiamine binding IEP Enrichment
MF GO:0030983 mismatched DNA binding IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
CC GO:0033202 DNA helicase complex IEP Enrichment
BP GO:0033554 cellular response to stress IEP Enrichment
BP GO:0033865 nucleoside bisphosphate metabolic process IEP Enrichment
BP GO:0033866 nucleoside bisphosphate biosynthetic process IEP Enrichment
BP GO:0033875 ribonucleoside bisphosphate metabolic process IEP Enrichment
BP GO:0034030 ribonucleoside bisphosphate biosynthetic process IEP Enrichment
BP GO:0034032 purine nucleoside bisphosphate metabolic process IEP Enrichment
BP GO:0034033 purine nucleoside bisphosphate biosynthetic process IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
BP GO:0042357 thiamine diphosphate metabolic process IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0043170 macromolecule metabolic process IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
BP GO:0044237 cellular metabolic process IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044255 cellular lipid metabolic process IEP Enrichment
BP GO:0044260 cellular macromolecule metabolic process IEP Enrichment
BP GO:0044281 small molecule metabolic process IEP Enrichment
BP GO:0044341 sodium-dependent phosphate transport IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
BP GO:0050896 response to stimulus IEP Enrichment
BP GO:0051276 chromosome organization IEP Enrichment
BP GO:0051716 cellular response to stimulus IEP Enrichment
BP GO:0070085 glycosylation IEP Enrichment
BP GO:0071704 organic substance metabolic process IEP Enrichment
BP GO:0072521 purine-containing compound metabolic process IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0097159 organic cyclic compound binding IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0140096 catalytic activity, acting on a protein IEP Enrichment
MF GO:0140097 catalytic activity, acting on DNA IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
MF GO:0140299 small molecule sensor activity IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
BP GO:1901362 organic cyclic compound biosynthetic process IEP Enrichment
MF GO:1901363 heterocyclic compound binding IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR020631 THF_DH/CycHdrlase_NAD-bd_dom 122 279
IPR020630 THF_DH/CycHdrlase_cat_dom 4 119
No external refs found!