CRN65985 (ileS)

Aliases : ileS

Description : Isoleucine--tRNA ligase [Ensembl]. tRNA synthetases class I (I, Anticodon-binding domain of tRNA, Zinc finger found in FPG and IleRS [Interproscan].

Gene families : OG_02_0000544 (OrthoFinder) Phylogenetic Tree(s): OG0000544_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: CRN65985
Cluster	HCCA: Cluster_35

Target	Alias	Description	ECC score	Gene Family Method
AAC73137	ileS, b0026	isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.08	OrthoFinder
AAL00306	spr1502, ileS	Isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.07	OrthoFinder
AAL19010	STM0046, ileS	isoleucine tRNA synthetase [Ensembl]. tRNA synthetases...	0.11	OrthoFinder
AEA93423	ileS, OG1RF_10736	isoleucine--tRNA ligase [Ensembl]. tRNA synthetases...	0.08	OrthoFinder
AGT26019	N559_4412	isoleucine--tRNA ligase [Ensembl]. Anticodon-binding...	0.09	OrthoFinder
AHY40269	ileS, CJ8421_05275	isoleucyl-tRNA ligase [Ensembl]. tRNA synthetases class...	0.04	OrthoFinder
AKP15383	ileS, WX61_01336	Isoleucine--tRNA ligase [Ensembl]. tRNA synthetases...	0.06	OrthoFinder
CBI65679	ileS, HPB8_122	isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.06	OrthoFinder
CCG26876	No alias	Isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.02	OrthoFinder
CCL19079	ileS, BN171_2870009	Isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.04	OrthoFinder
EDJ91762	CGSHi22421_08403	beta-hexosaminidase [Ensembl]. tRNA synthetases class I...	0.03	OrthoFinder
KNA57455	VCV51_030447	isoleucyl-tRNA synthetase [Ensembl]. tRNA synthetases...	0.14	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003747	translation release factor activity	IEP	Enrichment
MF	GO:0003864	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	IEP	Enrichment
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0004185	serine-type carboxypeptidase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005525	GTP binding	IEP	Enrichment
CC	GO:0005694	chromosome	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006259	DNA metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006415	translational termination	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006605	protein targeting	IEP	Enrichment
BP	GO:0006612	protein targeting to membrane	IEP	Enrichment
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006721	terpenoid metabolic process	IEP	Enrichment
BP	GO:0006886	intracellular protein transport	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
MF	GO:0008079	translation termination factor activity	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008135	translation factor activity, RNA binding	IEP	Enrichment
MF	GO:0008312	7S RNA binding	IEP	Enrichment
MF	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity	IEP	Enrichment
MF	GO:0008837	diaminopimelate epimerase activity	IEP	Enrichment
MF	GO:0009002	serine-type D-Ala-D-Ala carboxypeptidase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009059	macromolecule biosynthetic process	IEP	Enrichment
BP	GO:0009085	lysine biosynthetic process	IEP	Enrichment
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Enrichment
CC	GO:0009360	DNA polymerase III complex	IEP	Enrichment
BP	GO:0015939	pantothenate metabolic process	IEP	Enrichment
BP	GO:0015940	pantothenate biosynthetic process	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
BP	GO:0016114	terpenoid biosynthetic process	IEP	Enrichment
MF	GO:0016744	transketolase or transaldolase activity	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016855	racemase and epimerase activity, acting on amino acids and derivatives	IEP	Enrichment
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Enrichment
MF	GO:0016887	ATPase	IEP	Enrichment
BP	GO:0022411	cellular component disassembly	IEP	Enrichment
BP	GO:0031554	regulation of DNA-templated transcription, termination	IEP	Enrichment
MF	GO:0032977	membrane insertase activity	IEP	Enrichment
BP	GO:0032984	protein-containing complex disassembly	IEP	Enrichment
BP	GO:0033365	protein localization to organelle	IEP	Enrichment
MF	GO:0034061	DNA polymerase activity	IEP	Enrichment
BP	GO:0034613	cellular protein localization	IEP	Enrichment
MF	GO:0036361	racemase activity, acting on amino acids and derivatives	IEP	Enrichment
CC	GO:0042575	DNA polymerase complex	IEP	Enrichment
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	Enrichment
BP	GO:0043624	cellular protein complex disassembly	IEP	Enrichment
BP	GO:0043933	protein-containing complex subunit organization	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Enrichment
BP	GO:0045047	protein targeting to ER	IEP	Enrichment
MF	GO:0045182	translation regulator activity	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046451	diaminopimelate metabolic process	IEP	Enrichment
BP	GO:0046907	intracellular transport	IEP	Enrichment
MF	GO:0047661	amino-acid racemase activity	IEP	Enrichment
CC	GO:0048500	signal recognition particle	IEP	Enrichment
BP	GO:0051128	regulation of cellular component organization	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
BP	GO:0051641	cellular localization	IEP	Enrichment
BP	GO:0051649	establishment of localization in cell	IEP	Enrichment
BP	GO:0051668	localization within membrane	IEP	Enrichment
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Enrichment
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Enrichment
BP	GO:0070727	cellular macromolecule localization	IEP	Enrichment
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0072594	establishment of protein localization to organelle	IEP	Enrichment
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072657	protein localization to membrane	IEP	Enrichment
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	Enrichment
BP	GO:0090150	establishment of protein localization to membrane	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
MF	GO:0140104	molecular carrier activity	IEP	Enrichment
MF	GO:0140597	protein carrier activity	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
CC	GO:1990904	ribonucleoprotein complex	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR010663	Znf_FPG/IleRS	905	931
IPR002300	aa-tRNA-synth_Ia	28	646
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	691	847

External Links

Locus_tag	PAERUG_E11_London_26_VIM_2_06_13_00125

CRN65985 (ileS)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation