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  5. CRO13404

CRO13404 (dnaE)


Aliases : dnaE

Description : DNA polymerase III subunit alpha [Ensembl]. PHP domain, Helix-hairpin-helix motif, OB-fold nucleic acid binding domain, Bacterial DNA polymerase III alpha NTPase domain, Bacterial DNA polymerase III alpha subunit finger domain [Interproscan].


Gene families : OG_02_0000325 (OrthoFinder) Phylogenetic Tree(s): OG0000325_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CRO13404
Cluster HCCA: Cluster_35

Target Alias Description ECC score Gene Family Method Actions
AAC73295 dnaE, b0184 DNA polymerase III alpha subunit [Ensembl]. PHP domain,... 0.07 OrthoFinder
AAL19195 STM0231, dnaE DNA polymerase III, alpha subunit [Ensembl]. PHP domain,... 0.05 OrthoFinder
ADK86787 MPNE_0440 putative DNA polymerase III, alpha subunit [Ensembl].... 0.02 OrthoFinder
AGT25840 N559_4216 DNA polymerase III subunit alpha [Ensembl]. Bacterial... 0.04 OrthoFinder
AKP15394 dnaE, WX61_01347 DNA polymerase III subunit alpha [Ensembl]. PHP domain,... 0.04 OrthoFinder
CPD27156 dnaE, ERS093114_02435 DNA polymerase III alpha subunit [Ensembl]. PHP domain,... 0.02 OrthoFinder
EDJ91313 CGSHi22421_04398 DNA polymerase III subunit alpha [Ensembl]. PHP domain,... 0.04 OrthoFinder
KNA51808 VCV51_031511 DNA polymerase III [Ensembl]. PHP domain,... 0.06 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEA Interproscan
MF GO:0003824 catalytic activity IEA Interproscan
BP GO:0006260 DNA replication IEA Interproscan
MF GO:0008408 3'-5' exonuclease activity IEA Interproscan
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Enrichment
MF GO:0003678 DNA helicase activity IEP Enrichment
MF GO:0003690 double-stranded DNA binding IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003747 translation release factor activity IEP Enrichment
MF GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity IEP Enrichment
MF GO:0003916 DNA topoisomerase activity IEP Enrichment
MF GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEP Enrichment
MF GO:0004386 helicase activity IEP Enrichment
MF GO:0004611 phosphoenolpyruvate carboxykinase activity IEP Enrichment
MF GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity IEP Enrichment
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Enrichment
MF GO:0004813 alanine-tRNA ligase activity IEP Enrichment
MF GO:0004820 glycine-tRNA ligase activity IEP Enrichment
MF GO:0004832 valine-tRNA ligase activity IEP Enrichment
MF GO:0005315 inorganic phosphate transmembrane transporter activity IEP Enrichment
MF GO:0005524 ATP binding IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
CC GO:0005737 cytoplasm IEP Enrichment
BP GO:0006081 cellular aldehyde metabolic process IEP Enrichment
BP GO:0006082 organic acid metabolic process IEP Enrichment
BP GO:0006139 nucleobase-containing compound metabolic process IEP Enrichment
BP GO:0006259 DNA metabolic process IEP Enrichment
BP GO:0006265 DNA topological change IEP Enrichment
BP GO:0006281 DNA repair IEP Enrichment
BP GO:0006298 mismatch repair IEP Enrichment
BP GO:0006396 RNA processing IEP Enrichment
BP GO:0006399 tRNA metabolic process IEP Enrichment
BP GO:0006400 tRNA modification IEP Enrichment
BP GO:0006415 translational termination IEP Enrichment
BP GO:0006418 tRNA aminoacylation for protein translation IEP Enrichment
BP GO:0006419 alanyl-tRNA aminoacylation IEP Enrichment
BP GO:0006426 glycyl-tRNA aminoacylation IEP Enrichment
BP GO:0006438 valyl-tRNA aminoacylation IEP Enrichment
BP GO:0006520 cellular amino acid metabolic process IEP Enrichment
BP GO:0006605 protein targeting IEP Enrichment
BP GO:0006612 protein targeting to membrane IEP Enrichment
BP GO:0006613 cotranslational protein targeting to membrane IEP Enrichment
BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane IEP Enrichment
BP GO:0006629 lipid metabolic process IEP Enrichment
BP GO:0006720 isoprenoid metabolic process IEP Enrichment
BP GO:0006721 terpenoid metabolic process IEP Enrichment
BP GO:0006725 cellular aromatic compound metabolic process IEP Enrichment
BP GO:0006807 nitrogen compound metabolic process IEP Enrichment
BP GO:0006886 intracellular protein transport IEP Enrichment
BP GO:0006996 organelle organization IEP Enrichment
BP GO:0008033 tRNA processing IEP Enrichment
MF GO:0008079 translation termination factor activity IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
MF GO:0008135 translation factor activity, RNA binding IEP Enrichment
MF GO:0008168 methyltransferase activity IEP Enrichment
MF GO:0008173 RNA methyltransferase activity IEP Enrichment
MF GO:0008175 tRNA methyltransferase activity IEP Enrichment
MF GO:0008176 tRNA (guanine-N7-)-methyltransferase activity IEP Enrichment
BP GO:0008299 isoprenoid biosynthetic process IEP Enrichment
MF GO:0008312 7S RNA binding IEP Enrichment
BP GO:0008610 lipid biosynthetic process IEP Enrichment
MF GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase activity IEP Enrichment
MF GO:0008837 diaminopimelate epimerase activity IEP Enrichment
MF GO:0008883 glutamyl-tRNA reductase activity IEP Enrichment
BP GO:0009085 lysine biosynthetic process IEP Enrichment
BP GO:0009089 lysine biosynthetic process via diaminopimelate IEP Enrichment
BP GO:0009240 isopentenyl diphosphate biosynthetic process IEP Enrichment
BP GO:0009451 RNA modification IEP Enrichment
BP GO:0015939 pantothenate metabolic process IEP Enrichment
BP GO:0015940 pantothenate biosynthetic process IEP Enrichment
BP GO:0015969 guanosine tetraphosphate metabolic process IEP Enrichment
BP GO:0016043 cellular component organization IEP Enrichment
BP GO:0016053 organic acid biosynthetic process IEP Enrichment
BP GO:0016070 RNA metabolic process IEP Enrichment
BP GO:0016114 terpenoid biosynthetic process IEP Enrichment
MF GO:0016423 tRNA (guanine) methyltransferase activity IEP Enrichment
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Enrichment
MF GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor IEP Enrichment
MF GO:0016740 transferase activity IEP Enrichment
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Enrichment
MF GO:0016742 hydroxymethyl-, formyl- and related transferase activity IEP Enrichment
MF GO:0016744 transketolase or transaldolase activity IEP Enrichment
MF GO:0016779 nucleotidyltransferase activity IEP Enrichment
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Enrichment
MF GO:0016853 isomerase activity IEP Enrichment
MF GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives IEP Enrichment
MF GO:0016874 ligase activity IEP Enrichment
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Enrichment
MF GO:0016887 ATPase IEP Enrichment
MF GO:0017076 purine nucleotide binding IEP Enrichment
MF GO:0019001 guanyl nucleotide binding IEP Enrichment
BP GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Enrichment
BP GO:0019682 glyceraldehyde-3-phosphate metabolic process IEP Enrichment
BP GO:0019752 carboxylic acid metabolic process IEP Enrichment
BP GO:0022411 cellular component disassembly IEP Enrichment
MF GO:0030554 adenyl nucleotide binding IEP Enrichment
MF GO:0030983 mismatched DNA binding IEP Enrichment
BP GO:0031554 regulation of DNA-templated transcription, termination IEP Enrichment
MF GO:0032553 ribonucleotide binding IEP Enrichment
MF GO:0032555 purine ribonucleotide binding IEP Enrichment
MF GO:0032559 adenyl ribonucleotide binding IEP Enrichment
MF GO:0032561 guanyl ribonucleotide binding IEP Enrichment
MF GO:0032977 membrane insertase activity IEP Enrichment
BP GO:0032984 protein-containing complex disassembly IEP Enrichment
BP GO:0033365 protein localization to organelle IEP Enrichment
BP GO:0033865 nucleoside bisphosphate metabolic process IEP Enrichment
BP GO:0033875 ribonucleoside bisphosphate metabolic process IEP Enrichment
BP GO:0034032 purine nucleoside bisphosphate metabolic process IEP Enrichment
BP GO:0034035 purine ribonucleoside bisphosphate metabolic process IEP Enrichment
BP GO:0034470 ncRNA processing IEP Enrichment
BP GO:0034613 cellular protein localization IEP Enrichment
BP GO:0034641 cellular nitrogen compound metabolic process IEP Enrichment
BP GO:0034660 ncRNA metabolic process IEP Enrichment
MF GO:0035596 methylthiotransferase activity IEP Enrichment
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Enrichment
MF GO:0036094 small molecule binding IEP Enrichment
MF GO:0036361 racemase activity, acting on amino acids and derivatives IEP Enrichment
BP GO:0043038 amino acid activation IEP Enrichment
BP GO:0043039 tRNA aminoacylation IEP Enrichment
MF GO:0043138 3'-5' DNA helicase activity IEP Enrichment
MF GO:0043167 ion binding IEP Enrichment
MF GO:0043168 anion binding IEP Enrichment
BP GO:0043244 regulation of protein-containing complex disassembly IEP Enrichment
BP GO:0043436 oxoacid metabolic process IEP Enrichment
BP GO:0043624 cellular protein complex disassembly IEP Enrichment
BP GO:0043933 protein-containing complex subunit organization IEP Enrichment
BP GO:0044238 primary metabolic process IEP Enrichment
BP GO:0044255 cellular lipid metabolic process IEP Enrichment
BP GO:0044281 small molecule metabolic process IEP Enrichment
BP GO:0044283 small molecule biosynthetic process IEP Enrichment
BP GO:0045047 protein targeting to ER IEP Enrichment
MF GO:0045182 translation regulator activity IEP Enrichment
BP GO:0046394 carboxylic acid biosynthetic process IEP Enrichment
MF GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity IEP Enrichment
BP GO:0046451 diaminopimelate metabolic process IEP Enrichment
BP GO:0046483 heterocycle metabolic process IEP Enrichment
BP GO:0046490 isopentenyl diphosphate metabolic process IEP Enrichment
BP GO:0046907 intracellular transport IEP Enrichment
MF GO:0047661 amino-acid racemase activity IEP Enrichment
CC GO:0048500 signal recognition particle IEP Enrichment
MF GO:0050497 alkylthioltransferase activity IEP Enrichment
BP GO:0050992 dimethylallyl diphosphate biosynthetic process IEP Enrichment
BP GO:0050993 dimethylallyl diphosphate metabolic process IEP Enrichment
BP GO:0051128 regulation of cellular component organization IEP Enrichment
BP GO:0051276 chromosome organization IEP Enrichment
MF GO:0051536 iron-sulfur cluster binding IEP Enrichment
MF GO:0051540 metal cluster binding IEP Enrichment
BP GO:0051641 cellular localization IEP Enrichment
BP GO:0051649 establishment of localization in cell IEP Enrichment
BP GO:0051668 localization within membrane IEP Enrichment
MF GO:0051745 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity IEP Enrichment
MF GO:0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor IEP Enrichment
MF GO:0070567 cytidylyltransferase activity IEP Enrichment
BP GO:0070727 cellular macromolecule localization IEP Enrichment
BP GO:0070972 protein localization to endoplasmic reticulum IEP Enrichment
BP GO:0071103 DNA conformation change IEP Enrichment
BP GO:0071840 cellular component organization or biogenesis IEP Enrichment
BP GO:0072594 establishment of protein localization to organelle IEP Enrichment
BP GO:0072599 establishment of protein localization to endoplasmic reticulum IEP Enrichment
BP GO:0072657 protein localization to membrane IEP Enrichment
MF GO:0090079 translation regulator activity, nucleic acid binding IEP Enrichment
BP GO:0090150 establishment of protein localization to membrane IEP Enrichment
BP GO:0090304 nucleic acid metabolic process IEP Enrichment
MF GO:0097367 carbohydrate derivative binding IEP Enrichment
MF GO:0140097 catalytic activity, acting on DNA IEP Enrichment
MF GO:0140098 catalytic activity, acting on RNA IEP Enrichment
MF GO:0140101 catalytic activity, acting on a tRNA IEP Enrichment
MF GO:0140104 molecular carrier activity IEP Enrichment
MF GO:0140597 protein carrier activity IEP Enrichment
MF GO:1901265 nucleoside phosphate binding IEP Enrichment
BP GO:1901360 organic cyclic compound metabolic process IEP Enrichment
BP GO:1901564 organonitrogen compound metabolic process IEP Enrichment
CC GO:1990904 ribonucleoprotein complex IEP Enrichment
InterPro domains Description Start Stop
IPR029460 DNAPol_HHH 810 895
IPR040982 DNA_pol3_finger 562 736
IPR004013 PHP_dom 7 171
IPR011708 DNA_pol3_alpha_NTPase_dom 291 559
IPR004365 NA-bd_OB_tRNA 1009 1083
Locus_tag PAERUG_E11_London_26_VIM_2_06_13_01596