AEA94505 (proS, OG1RF_11818)

Aliases : proS, OG1RF_11818

Description : proline--tRNA ligase [Ensembl]. Anticodon binding domain, Aminoacyl-tRNA editing domain, tRNA synthetase class II core domain (G [Interproscan].

Gene families : OG_02_0000443 (OrthoFinder) Phylogenetic Tree(s): OG0000443_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AEA94505
Cluster	HCCA: Cluster_12

Target	Alias	Description	ECC score	Gene Family Method
AAC73305	proS, b0194	prolyl-tRNA synthetase [Ensembl]. Anticodon binding...	0.08	OrthoFinder
AAL19205	STM0242, proS	proline tRNA synthetase [Ensembl]. Anticodon binding...	0.06	OrthoFinder
AGT25831	N559_4206	prolyl-tRNA synthetase [Ensembl]. tRNA synthetase class...	0.03	OrthoFinder
AKI49315	proS, L2625_01409	prolyl-tRNA synthetase [Ensembl]. Aminoacyl-tRNA...	0.04	OrthoFinder
AKP14223	proS, WX61_00134	Proline--tRNA ligase [Ensembl]. Anticodon binding...	0.07	OrthoFinder
CRN72909	proS	Proline--tRNA ligase [Ensembl]. Anticodon binding...	0.04	OrthoFinder
KNA56974	VCV51_030590	prolyl-tRNA synthetase [Ensembl]. Anticodon binding...	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0002161	aminoacyl-tRNA editing activity	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0052689	carboxylic ester hydrolase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEP	Enrichment
BP	GO:0000921	septin ring assembly	IEP	Enrichment
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004476	mannose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004743	pyruvate kinase activity	IEP	Enrichment
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Enrichment
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
CC	GO:0005856	cytoskeleton	IEP	Enrichment
CC	GO:0005940	septin ring	IEP	Enrichment
BP	GO:0005975	carbohydrate metabolic process	IEP	Enrichment
BP	GO:0006090	pyruvate metabolic process	IEP	Enrichment
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Enrichment
BP	GO:0006096	glycolytic process	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Enrichment
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006612	protein targeting to membrane	IEP	Enrichment
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006757	ATP generation from ADP	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0007010	cytoskeleton organization	IEP	Enrichment
MF	GO:0008270	zinc ion binding	IEP	Enrichment
BP	GO:0009056	catabolic process	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
BP	GO:0016052	carbohydrate catabolic process	IEP	Enrichment
BP	GO:0016226	iron-sulfur cluster assembly	IEP	Enrichment
BP	GO:0016310	phosphorylation	IEP	Enrichment
MF	GO:0016832	aldehyde-lyase activity	IEP	Enrichment
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Enrichment
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
BP	GO:0022607	cellular component assembly	IEP	Enrichment
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Enrichment
MF	GO:0030955	potassium ion binding	IEP	Enrichment
BP	GO:0031106	septin ring organization	IEP	Enrichment
BP	GO:0031163	metallo-sulfur cluster assembly	IEP	Enrichment
MF	GO:0031420	alkali metal ion binding	IEP	Enrichment
CC	GO:0032156	septin cytoskeleton	IEP	Enrichment
BP	GO:0032185	septin cytoskeleton organization	IEP	Enrichment
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Enrichment
BP	GO:0033365	protein localization to organelle	IEP	Enrichment
BP	GO:0034613	cellular protein localization	IEP	Enrichment
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Enrichment
BP	GO:0042254	ribosome biogenesis	IEP	Enrichment
MF	GO:0043169	cation binding	IEP	Enrichment
BP	GO:0044085	cellular component biogenesis	IEP	Enrichment
BP	GO:0045047	protein targeting to ER	IEP	Enrichment
BP	GO:0046031	ADP metabolic process	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
MF	GO:0046872	metal ion binding	IEP	Enrichment
MF	GO:0046914	transition metal ion binding	IEP	Enrichment
BP	GO:0046939	nucleotide phosphorylation	IEP	Enrichment
MF	GO:0051499	D-aminoacyl-tRNA deacylase activity	IEP	Enrichment
BP	GO:0051668	localization within membrane	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
BP	GO:0070727	cellular macromolecule localization	IEP	Enrichment
BP	GO:0070925	organelle assembly	IEP	Enrichment
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0072594	establishment of protein localization to organelle	IEP	Enrichment
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Enrichment
BP	GO:0072657	protein localization to membrane	IEP	Enrichment
BP	GO:0090150	establishment of protein localization to membrane	IEP	Enrichment
BP	GO:1901575	organic substance catabolic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004154	Anticodon-bd	475	561
IPR002314	aa-tRNA-synt_IIb	94	456
IPR007214	YbaK/aa-tRNA-synth-assoc-dom	257	373

External Links

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AEA94505 (proS, OG1RF_11818)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation