AAC73140 (ispH, b0029)

Aliases : ispH, b0029

Description : 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4Fe-4S protein [Ensembl]. LytB protein [Interproscan].

Gene families : OG_02_0000852 (OrthoFinder) Phylogenetic Tree(s): OG0000852_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC73140
Cluster	HCCA: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method
AAL19013	STM0049, lytB	regulates the activity of guanosine...	0.11	OrthoFinder
AGT26016	N559_4409	4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Ensembl].	0.16	OrthoFinder
AKP15386	ispH, WX61_01339	4-hydroxy-3-methylbut-2-enyl diphosphate reductase...	0.03	OrthoFinder
CRN66060	ispH	4-hydroxy-3-methylbut-2-enyl diphosphate reductase...	0.04	OrthoFinder
EDJ91807	CGSHi22421_08628	4-hydroxy-3-methylbut-2-enyl diphosphate reductase...	0.05	OrthoFinder
KNA57458	VCV51_030448	hydroxymethylbutenyl pyrophosphate reductase [Ensembl]....	0.05	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006081	cellular aldehyde metabolic process	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006090	pyruvate metabolic process	None	Extended
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006644	phospholipid metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0008654	phospholipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	None	Extended
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	None	Extended
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEA	Interproscan
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0032787	monocarboxylic acid metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046490	isopentenyl diphosphate metabolic process	None	Extended
MF	GO:0046872	metal ion binding	IEA	Interproscan
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEA	Interproscan
BP	GO:0050993	dimethylallyl diphosphate metabolic process	None	Extended
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Enrichment
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Enrichment
MF	GO:0003919	FMN adenylyltransferase activity	IEP	Enrichment
MF	GO:0003989	acetyl-CoA carboxylase activity	IEP	Enrichment
MF	GO:0004175	endopeptidase activity	IEP	Enrichment
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Enrichment
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0004652	polynucleotide adenylyltransferase activity	IEP	Enrichment
MF	GO:0004810	tRNA adenylyltransferase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0005524	ATP binding	IEP	Enrichment
MF	GO:0005539	glycosaminoglycan binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006323	DNA packaging	IEP	Enrichment
BP	GO:0006364	rRNA processing	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006633	fatty acid biosynthetic process	IEP	Enrichment
BP	GO:0006643	membrane lipid metabolic process	IEP	Enrichment
BP	GO:0006664	glycolipid metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006766	vitamin metabolic process	IEP	Enrichment
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Enrichment
BP	GO:0006771	riboflavin metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
BP	GO:0007059	chromosome segregation	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Enrichment
BP	GO:0008360	regulation of cell shape	IEP	Enrichment
MF	GO:0008531	riboflavin kinase activity	IEP	Enrichment
MF	GO:0008716	D-alanine-D-alanine ligase activity	IEP	Enrichment
MF	GO:0008915	lipid-A-disaccharide synthase activity	IEP	Enrichment
MF	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
BP	GO:0009231	riboflavin biosynthetic process	IEP	Enrichment
BP	GO:0009245	lipid A biosynthetic process	IEP	Enrichment
BP	GO:0009247	glycolipid biosynthetic process	IEP	Enrichment
CC	GO:0009295	nucleoid	IEP	Enrichment
BP	GO:0009311	oligosaccharide metabolic process	IEP	Enrichment
BP	GO:0009312	oligosaccharide biosynthetic process	IEP	Enrichment
CC	GO:0009317	acetyl-CoA carboxylase complex	IEP	Enrichment
CC	GO:0009349	riboflavin synthase complex	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
BP	GO:0016072	rRNA metabolic process	IEP	Enrichment
MF	GO:0016421	CoA carboxylase activity	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016758	hexosyltransferase activity	IEP	Enrichment
MF	GO:0016779	nucleotidyltransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
MF	GO:0016885	ligase activity, forming carbon-carbon bonds	IEP	Enrichment
BP	GO:0017038	protein import	IEP	Enrichment
MF	GO:0017076	purine nucleotide binding	IEP	Enrichment
BP	GO:0022603	regulation of anatomical structure morphogenesis	IEP	Enrichment
BP	GO:0022604	regulation of cell morphogenesis	IEP	Enrichment
BP	GO:0030258	lipid modification	IEP	Enrichment
BP	GO:0030259	lipid glycosylation	IEP	Enrichment
BP	GO:0030261	chromosome condensation	IEP	Enrichment
MF	GO:0030554	adenyl nucleotide binding	IEP	Enrichment
MF	GO:0032553	ribonucleotide binding	IEP	Enrichment
MF	GO:0032555	purine ribonucleotide binding	IEP	Enrichment
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Enrichment
CC	GO:0032991	protein-containing complex	IEP	Enrichment
BP	GO:0034470	ncRNA processing	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Enrichment
MF	GO:0036094	small molecule binding	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Enrichment
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0042834	peptidoglycan binding	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
MF	GO:0043168	anion binding	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
BP	GO:0046467	membrane lipid biosynthetic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046493	lipid A metabolic process	IEP	Enrichment
BP	GO:0050793	regulation of developmental process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0051287	NAD binding	IEP	Enrichment
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Enrichment
MF	GO:0070001	aspartic-type peptidase activity	IEP	Enrichment
BP	GO:0070085	glycosylation	IEP	Enrichment
MF	GO:0070566	adenylyltransferase activity	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0097159	organic cyclic compound binding	IEP	Enrichment
MF	GO:0097367	carbohydrate derivative binding	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
MF	GO:1901265	nucleoside phosphate binding	IEP	Enrichment
BP	GO:1901269	lipooligosaccharide metabolic process	IEP	Enrichment
BP	GO:1901271	lipooligosaccharide biosynthetic process	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
MF	GO:1901363	heterocyclic compound binding	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
CC	GO:1902494	catalytic complex	IEP	Enrichment
BP	GO:1903509	liposaccharide metabolic process	IEP	Enrichment
MF	GO:1990817	RNA adenylyltransferase activity	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR003451	LytB/IspH	3	282

External Links

UniProtKB	P62623

AAC73140 (ispH, b0029)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation