AAC73197 (murF, b0086)

Aliases : murF, b0086

Description : UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase [Ensembl]. Mur ligase family, Mur ligase middle domain [Interproscan].

Gene families : OG_02_0000378 (OrthoFinder) Phylogenetic Tree(s): OG0000378_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC73197
Cluster	HCCA: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method
AAL00318	spr1514, murF	UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-...	0.03	OrthoFinder
AAL19088	STM0124, murF	D-alanine:D-alanine-adding enzyme [Ensembl]. Mur ligase...	0.21	OrthoFinder
AEA93262	ppx, OG1RF_10575	exopolyphosphatase [Ensembl]. Mur ligase family, Mur...	0.03	OrthoFinder
AGT25953	N559_4340	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine...	0.13	OrthoFinder
AHY40010	CJ8421_03905	Mur ligase family protein [Ensembl]. Mur ligase middle...	0.03	OrthoFinder
AKI48804	murF, L2625_00877	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine...	0.06	OrthoFinder
AKP14610	murF, WX61_00529	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine...	0.07	OrthoFinder
CBI66504	murF, HPB8_947	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,...	0.04	OrthoFinder
CCG27254	No alias	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate...	0.05	OrthoFinder
CCL19117	murF, BN171_2870047	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine...	0.05	OrthoFinder
CCP44933	murF, Rv2157c	Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,...	0.03	OrthoFinder
CPD23446	murF, ERS093114_02347	UDP-N-acetylmuramoylalanyl-D-glutamyl-2%2C6-diaminopimela...	0.03	OrthoFinder
CRP08587	murF	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine...	0.07	OrthoFinder
EDJ91936	murE, CGSHi22421_09273	UDP-N-acetylmuramoylalanyl-D-glutamate--2,...	0.03	OrthoFinder
EDJ91938	murE, CGSHi22421_09283	UDP-N-acetylmuramoylalanyl-D-glutamate--2,...	0.08	OrthoFinder
KNA53283	VCV51_031618	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine...	0.12	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	IEA	Interproscan
MF	GO:0016874	ligase activity	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
MF	GO:0005539	glycosaminoglycan binding	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Enrichment
BP	GO:0006323	DNA packaging	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006644	phospholipid metabolic process	IEP	Enrichment
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Enrichment
BP	GO:0006766	vitamin metabolic process	IEP	Enrichment
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Enrichment
BP	GO:0006771	riboflavin metabolic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0006807	nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
BP	GO:0007059	chromosome segregation	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
BP	GO:0008654	phospholipid biosynthetic process	IEP	Enrichment
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEP	Enrichment
MF	GO:0008703	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	IEP	Enrichment
MF	GO:0008716	D-alanine-D-alanine ligase activity	IEP	Enrichment
MF	GO:0008961	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity	IEP	Enrichment
MF	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
BP	GO:0009143	nucleoside triphosphate catabolic process	IEP	Enrichment
BP	GO:0009231	riboflavin biosynthetic process	IEP	Enrichment
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Enrichment
CC	GO:0009295	nucleoid	IEP	Enrichment
CC	GO:0009349	riboflavin synthase complex	IEP	Enrichment
BP	GO:0009987	cellular process	IEP	Enrichment
BP	GO:0010033	response to organic substance	IEP	Enrichment
BP	GO:0016070	RNA metabolic process	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Enrichment
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016740	transferase activity	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Enrichment
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016859	cis-trans isomerase activity	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
BP	GO:0017038	protein import	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Enrichment
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0030258	lipid modification	IEP	Enrichment
BP	GO:0030259	lipid glycosylation	IEP	Enrichment
BP	GO:0030261	chromosome condensation	IEP	Enrichment
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
BP	GO:0042157	lipoprotein metabolic process	IEP	Enrichment
BP	GO:0042158	lipoprotein biosynthetic process	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Enrichment
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0042834	peptidoglycan binding	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043170	macromolecule metabolic process	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044237	cellular metabolic process	IEP	Enrichment
BP	GO:0044238	primary metabolic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0046483	heterocycle metabolic process	IEP	Enrichment
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Enrichment
BP	GO:0050896	response to stimulus	IEP	Enrichment
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0051287	NAD binding	IEP	Enrichment
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEP	Enrichment
BP	GO:0061024	membrane organization	IEP	Enrichment
MF	GO:0070402	NADPH binding	IEP	Enrichment
MF	GO:0070567	cytidylyltransferase activity	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0071704	organic substance metabolic process	IEP	Enrichment
BP	GO:0090304	nucleic acid metabolic process	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR004101	Mur_ligase_C	313	394
IPR000713	Mur_ligase_N	26	80
IPR013221	Mur_ligase_cen	106	292

External Links

UniProtKB	P11880

AAC73197 (murF, b0086)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation