CRP36119 (leuS)


Aliases : leuS

Description : Leucine--tRNA ligase [Ensembl]. Leucyl-tRNA synthetase, tRNA synthetases class I (I, tRNA synthetases class I (M), Anticodon-binding domain of tRNA [Interproscan].


Gene families : OG_02_0000728 (OrthoFinder) Phylogenetic Tree(s): OG0000728_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: CRP36119
Cluster HCCA: Cluster_35

Target Alias Description ECC score Gene Family Method Actions
AAC73743 leuS, b0642 leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA... 0.11 OrthoFinder
AAK99039 spr0235, leuS Leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA... 0.03 OrthoFinder
AAL19599 STM0648, leuS leucine tRNA synthetase [Ensembl]. Leucyl-tRNA... 0.09 OrthoFinder
AGT25290 N559_3648 leucyl-tRNA synthetase [Ensembl]. Domain 2,... 0.06 OrthoFinder
AHY40297 leuS, CJ8421_05425 leucyl-tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,... 0.03 OrthoFinder
AKI49656 leuS, L2625_01769 leucyl-tRNA synthetase [Ensembl]. Methionyl/Leucyl tRNA... 0.08 OrthoFinder
AKP15329 leuS, WX61_01280 Leucine--tRNA ligase [Ensembl]. Leucyl-tRNA synthetase,... 0.06 OrthoFinder
CBI67232 leuS, HPB8_1675 leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA... 0.07 OrthoFinder
CCG26473 No alias Leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA... 0.03 OrthoFinder
EDJ91709 leuS, CGSHi22421_08138 leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA... 0.06 OrthoFinder
KNA56394 VCV51_032954 leucyl-tRNA synthetase [Ensembl]. Leucyl-tRNA... 0.09 OrthoFinder

Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEA Interproscan
MF GO:0002161 aminoacyl-tRNA editing activity IEA Interproscan
MF GO:0004812 aminoacyl-tRNA ligase activity IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0006418 tRNA aminoacylation for protein translation IEA Interproscan
Type GO Term Name Evidence Source
MF GO:0000049 tRNA binding IEP Enrichment
BP GO:0000105 histidine biosynthetic process IEP Enrichment
MF GO:0003676 nucleic acid binding IEP Enrichment
MF GO:0003723 RNA binding IEP Enrichment
MF GO:0003747 translation release factor activity IEP Enrichment
MF GO:0003916 DNA topoisomerase activity IEP Enrichment
MF GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEP Enrichment
MF GO:0003919 FMN adenylyltransferase activity IEP Enrichment
MF GO:0004017 adenylate kinase activity IEP Enrichment
MF GO:0004019 adenylosuccinate synthase activity IEP Enrichment
MF GO:0004055 argininosuccinate synthase activity IEP Enrichment
MF GO:0004107 chorismate synthase activity IEP Enrichment
MF GO:0004177 aminopeptidase activity IEP Enrichment
MF GO:0004399 histidinol dehydrogenase activity IEP Enrichment
MF GO:0004470 malic enzyme activity IEP Enrichment
MF GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity IEP Enrichment
MF GO:0004665 prephenate dehydrogenase (NADP+) activity IEP Enrichment
MF GO:0004751 ribose-5-phosphate isomerase activity IEP Enrichment
MF GO:0004813 alanine-tRNA ligase activity IEP Enrichment
MF GO:0004814 arginine-tRNA ligase activity IEP Enrichment
MF GO:0004820 glycine-tRNA ligase activity IEP Enrichment
MF GO:0004826 phenylalanine-tRNA ligase activity IEP Enrichment
MF GO:0005525 GTP binding IEP Enrichment
BP GO:0006259 DNA metabolic process IEP Enrichment
BP GO:0006260 DNA replication IEP Enrichment
BP GO:0006265 DNA topological change IEP Enrichment
BP GO:0006415 translational termination IEP Enrichment
BP GO:0006419 alanyl-tRNA aminoacylation IEP Enrichment
BP GO:0006420 arginyl-tRNA aminoacylation IEP Enrichment
BP GO:0006426 glycyl-tRNA aminoacylation IEP Enrichment
BP GO:0006432 phenylalanyl-tRNA aminoacylation IEP Enrichment
BP GO:0006526 arginine biosynthetic process IEP Enrichment
BP GO:0006547 histidine metabolic process IEP Enrichment
BP GO:0006570 tyrosine metabolic process IEP Enrichment
BP GO:0006571 tyrosine biosynthetic process IEP Enrichment
BP GO:0006721 terpenoid metabolic process IEP Enrichment
BP GO:0006766 vitamin metabolic process IEP Enrichment
BP GO:0006767 water-soluble vitamin metabolic process IEP Enrichment
BP GO:0006771 riboflavin metabolic process IEP Enrichment
BP GO:0006996 organelle organization IEP Enrichment
MF GO:0008079 translation termination factor activity IEP Enrichment
MF GO:0008094 ATPase, acting on DNA IEP Enrichment
MF GO:0008135 translation factor activity, RNA binding IEP Enrichment
MF GO:0008238 exopeptidase activity IEP Enrichment
MF GO:0008531 riboflavin kinase activity IEP Enrichment
BP GO:0008652 cellular amino acid biosynthetic process IEP Enrichment
MF GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase activity IEP Enrichment
MF GO:0008837 diaminopimelate epimerase activity IEP Enrichment
MF GO:0008977 prephenate dehydrogenase (NAD+) activity IEP Enrichment
BP GO:0009052 pentose-phosphate shunt, non-oxidative branch IEP Enrichment
BP GO:0009058 biosynthetic process IEP Enrichment
BP GO:0009059 macromolecule biosynthetic process IEP Enrichment
BP GO:0009072 aromatic amino acid family metabolic process IEP Enrichment
BP GO:0009073 aromatic amino acid family biosynthetic process IEP Enrichment
BP GO:0009085 lysine biosynthetic process IEP Enrichment
BP GO:0009089 lysine biosynthetic process via diaminopimelate IEP Enrichment
BP GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway IEP Enrichment
BP GO:0009110 vitamin biosynthetic process IEP Enrichment
BP GO:0009231 riboflavin biosynthetic process IEP Enrichment
CC GO:0009349 riboflavin synthase complex IEP Enrichment
BP GO:0016043 cellular component organization IEP Enrichment
BP GO:0016053 organic acid biosynthetic process IEP Enrichment
BP GO:0016114 terpenoid biosynthetic process IEP Enrichment
MF GO:0016740 transferase activity IEP Enrichment
MF GO:0016744 transketolase or transaldolase activity IEP Enrichment
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Enrichment
MF GO:0016776 phosphotransferase activity, phosphate group as acceptor IEP Enrichment
MF GO:0016779 nucleotidyltransferase activity IEP Enrichment
MF GO:0016838 carbon-oxygen lyase activity, acting on phosphates IEP Enrichment
MF GO:0016853 isomerase activity IEP Enrichment
MF GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives IEP Enrichment
MF GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses IEP Enrichment
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Enrichment
MF GO:0016887 ATPase IEP Enrichment
BP GO:0018130 heterocycle biosynthetic process IEP Enrichment
MF GO:0019205 nucleobase-containing compound kinase activity IEP Enrichment
BP GO:0019438 aromatic compound biosynthetic process IEP Enrichment
BP GO:0022411 cellular component disassembly IEP Enrichment
MF GO:0030145 manganese ion binding IEP Enrichment
BP GO:0031554 regulation of DNA-templated transcription, termination IEP Enrichment
BP GO:0032984 protein-containing complex disassembly IEP Enrichment
MF GO:0036361 racemase activity, acting on amino acids and derivatives IEP Enrichment
BP GO:0042364 water-soluble vitamin biosynthetic process IEP Enrichment
BP GO:0042726 flavin-containing compound metabolic process IEP Enrichment
BP GO:0042727 flavin-containing compound biosynthetic process IEP Enrichment
MF GO:0043138 3'-5' DNA helicase activity IEP Enrichment
BP GO:0043244 regulation of protein-containing complex disassembly IEP Enrichment
BP GO:0043624 cellular protein complex disassembly IEP Enrichment
BP GO:0043933 protein-containing complex subunit organization IEP Enrichment
BP GO:0044249 cellular biosynthetic process IEP Enrichment
BP GO:0044260 cellular macromolecule metabolic process IEP Enrichment
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Enrichment
BP GO:0044283 small molecule biosynthetic process IEP Enrichment
MF GO:0045182 translation regulator activity IEP Enrichment
BP GO:0046394 carboxylic acid biosynthetic process IEP Enrichment
BP GO:0046451 diaminopimelate metabolic process IEP Enrichment
MF GO:0047661 amino-acid racemase activity IEP Enrichment
MF GO:0050145 nucleoside monophosphate kinase activity IEP Enrichment
BP GO:0051128 regulation of cellular component organization IEP Enrichment
BP GO:0051276 chromosome organization IEP Enrichment
MF GO:0070566 adenylyltransferase activity IEP Enrichment
BP GO:0071103 DNA conformation change IEP Enrichment
BP GO:0071840 cellular component organization or biogenesis IEP Enrichment
MF GO:0090079 translation regulator activity, nucleic acid binding IEP Enrichment
MF GO:0140097 catalytic activity, acting on DNA IEP Enrichment
BP GO:1901135 carbohydrate derivative metabolic process IEP Enrichment
BP GO:1901362 organic cyclic compound biosynthetic process IEP Enrichment
BP GO:1901566 organonitrogen compound biosynthetic process IEP Enrichment
BP GO:1901576 organic substance biosynthetic process IEP Enrichment
BP GO:1901605 alpha-amino acid metabolic process IEP Enrichment
BP GO:1901607 alpha-amino acid biosynthetic process IEP Enrichment
InterPro domains Description Start Stop
IPR013155 M/V/L/I-tRNA-synth_anticd-bd 715 834
IPR025709 Leu_tRNA-synth_edit 221 413
IPR015413 Methionyl/Leucyl_tRNA_Synth 39 171
IPR002300 aa-tRNA-synth_Ia 428 584
IPR002300 aa-tRNA-synth_Ia 631 665