AAC74198 (mfd, b1114)

Aliases : mfd, b1114

Description : transcription-repair coupling factor [Ensembl]. CarD-like/TRCF domain, DEAD/DEAH box helicase, UvrB interaction domain, Helicase conserved C-terminal domain [Interproscan].

Gene families : OG_02_0000637 (OrthoFinder) Phylogenetic Tree(s): OG0000637_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC74198
Cluster	HCCA: Cluster_39

Target	Alias	Description	ECC score	Gene Family Method
AAL20145	STM1216, mfd	transcription-repair coupling factor [Ensembl]....	0.09	OrthoFinder
AGT24835	N559_3175	transcription-repair coupling factor [Ensembl]. TRCF...	0.04	OrthoFinder
AKP14165	mfd, WX61_00076	Transcription-repair-coupling factor [Ensembl]....	0.03	OrthoFinder
CBI67226	mfd, HPB8_1669	transcription-repair coupling factor (superfamily II...	0.04	OrthoFinder
CPD35390	mfd, ERS093114_02650	Transcription-repair coupling factor [Ensembl]....	0.03	OrthoFinder
EDJ91013	CGSHi22421_02786	transcription-repair coupling factor [Ensembl]....	0.04	OrthoFinder
KNA59432	VCV51_031278	transcription-repair coupling factor [Ensembl]....	0.04	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001514	selenocysteine incorporation	IEP	Enrichment
MF	GO:0003690	double-stranded DNA binding	IEP	Enrichment
MF	GO:0003824	catalytic activity	IEP	Enrichment
MF	GO:0003855	3-dehydroquinate dehydratase activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0004175	endopeptidase activity	IEP	Enrichment
MF	GO:0004222	metalloendopeptidase activity	IEP	Enrichment
MF	GO:0004418	hydroxymethylbilane synthase activity	IEP	Enrichment
MF	GO:0004476	mannose-6-phosphate isomerase activity	IEP	Enrichment
MF	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity	IEP	Enrichment
MF	GO:0004518	nuclease activity	IEP	Enrichment
MF	GO:0004527	exonuclease activity	IEP	Enrichment
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEP	Enrichment
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004832	valine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
CC	GO:0005737	cytoplasm	IEP	Enrichment
BP	GO:0006082	organic acid metabolic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006323	DNA packaging	IEP	Enrichment
BP	GO:0006399	tRNA metabolic process	IEP	Enrichment
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006451	translational readthrough	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006520	cellular amino acid metabolic process	IEP	Enrichment
BP	GO:0006766	vitamin metabolic process	IEP	Enrichment
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
BP	GO:0007059	chromosome segregation	IEP	Enrichment
MF	GO:0008233	peptidase activity	IEP	Enrichment
MF	GO:0008237	metallopeptidase activity	IEP	Enrichment
BP	GO:0008614	pyridoxine metabolic process	IEP	Enrichment
BP	GO:0008615	pyridoxine biosynthetic process	IEP	Enrichment
MF	GO:0008703	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	IEP	Enrichment
MF	GO:0008852	exodeoxyribonuclease I activity	IEP	Enrichment
MF	GO:0008964	phosphoenolpyruvate carboxylase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
CC	GO:0009295	nucleoid	IEP	Enrichment
BP	GO:0009435	NAD biosynthetic process	IEP	Enrichment
BP	GO:0015977	carbon fixation	IEP	Enrichment
MF	GO:0016757	glycosyltransferase activity	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016831	carboxy-lyase activity	IEP	Enrichment
MF	GO:0016835	carbon-oxygen lyase activity	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
MF	GO:0016874	ligase activity	IEP	Enrichment
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019538	protein metabolic process	IEP	Enrichment
BP	GO:0019752	carboxylic acid metabolic process	IEP	Enrichment
BP	GO:0030261	chromosome condensation	IEP	Enrichment
MF	GO:0030983	mismatched DNA binding	IEP	Enrichment
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Enrichment
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Enrichment
MF	GO:0033856	pyridoxine 5'-phosphate synthase activity	IEP	Enrichment
BP	GO:0034660	ncRNA metabolic process	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
BP	GO:0042816	vitamin B6 metabolic process	IEP	Enrichment
BP	GO:0042819	vitamin B6 biosynthetic process	IEP	Enrichment
BP	GO:0043038	amino acid activation	IEP	Enrichment
BP	GO:0043039	tRNA aminoacylation	IEP	Enrichment
BP	GO:0043436	oxoacid metabolic process	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0044281	small molecule metabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Enrichment
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Enrichment
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901617	organic hydroxy compound biosynthetic process	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR011545	DEAD/DEAH_box_helicase_dom	602	762
IPR003711	CarD-like/TRCF_domain	477	572
IPR041471	UvrB_inter	129	217
IPR001650	Helicase_C	803	906
IPR005118	TRCF_C	1006	1098

External Links

UniProtKB	P30958

AAC74198 (mfd, b1114)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation