AAC77215 (valS, b4258)

Aliases : valS, b4258

Description : valyl-tRNA synthetase [Ensembl]. tRNA synthetases class I (I, Anticodon-binding domain of tRNA, Valyl tRNA synthetase tRNA binding arm [Interproscan].

Gene families : OG_02_0000453 (OrthoFinder) Phylogenetic Tree(s): OG0000453_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AAC77215
Cluster	HCCA: Cluster_37

Target	Alias	Description	ECC score	Gene Family Method
AAK99296	spr0492, valS	Valyl-tRNA synthetase [Ensembl]. tRNA synthetases class...	0.04	OrthoFinder
AAL23294	STM4475, valS	valine tRNA synthetase [Ensembl]. tRNA synthetases class...	0.24	OrthoFinder
AEA94918	valS, OG1RF_12231	valine--tRNA ligase [Ensembl]. tRNA synthetases class I...	0.09	OrthoFinder
AGT26221	N559_4627	valine--tRNA ligase [Ensembl]. Anticodon-binding domain...	0.19	OrthoFinder
AHY39989	valS, CJ8421_03800	valyl-tRNA ligase [Ensembl]. tRNA synthetases class I...	0.04	OrthoFinder
AKI49549	valS, L2625_01656	valyl-tRNA synthetase [Ensembl]....	0.07	OrthoFinder
AKP15156	valS, WX61_01102	Valine--tRNA ligase [Ensembl]. tRNA synthetases class I...	0.07	OrthoFinder
CBI65905	valS, HPB8_348	valyl-tRNA synthetase [Ensembl]. tRNA synthetases class...	0.05	OrthoFinder
CCG27458	No alias	Valyl-tRNA synthetase [Ensembl]. tRNA synthetases class...	0.04	OrthoFinder
CCP45241	valS, Rv2448c	Probable valyl-tRNA synthase protein ValS (valyl-tRNA...	0.04	OrthoFinder
CPC85215	valS, ERS093114_01485	Valyl-tRNA synthetase [Ensembl]. tRNA synthetases class...	0.06	OrthoFinder
CRO02535	valS	Valine--tRNA ligase [Ensembl]. tRNA synthetases class I...	0.07	OrthoFinder
KNA54835	VCV51_031686	valyl-tRNA synthetase [Ensembl]. tRNA synthetases class...	0.09	OrthoFinder

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan
MF	GO:0004832	valine-tRNA ligase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	Interproscan
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	IEA	Interproscan
BP	GO:0006438	valyl-tRNA aminoacylation	IEA	Interproscan
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000049	tRNA binding	IEP	Enrichment
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Enrichment
MF	GO:0003676	nucleic acid binding	IEP	Enrichment
MF	GO:0003723	RNA binding	IEP	Enrichment
MF	GO:0003916	DNA topoisomerase activity	IEP	Enrichment
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Enrichment
MF	GO:0003989	acetyl-CoA carboxylase activity	IEP	Enrichment
MF	GO:0004107	chorismate synthase activity	IEP	Enrichment
MF	GO:0004312	fatty acid synthase activity	IEP	Enrichment
MF	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEP	Enrichment
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	IEP	Enrichment
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Enrichment
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Enrichment
MF	GO:0004592	pantoate-beta-alanine ligase activity	IEP	Enrichment
MF	GO:0004611	phosphoenolpyruvate carboxykinase activity	IEP	Enrichment
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Enrichment
MF	GO:0004853	uroporphyrinogen decarboxylase activity	IEP	Enrichment
MF	GO:0005216	ion channel activity	IEP	Enrichment
MF	GO:0005261	cation channel activity	IEP	Enrichment
MF	GO:0005539	glycosaminoglycan binding	IEP	Enrichment
BP	GO:0006163	purine nucleotide metabolic process	IEP	Enrichment
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0006260	DNA replication	IEP	Enrichment
BP	GO:0006265	DNA topological change	IEP	Enrichment
BP	GO:0006323	DNA packaging	IEP	Enrichment
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Enrichment
BP	GO:0006508	proteolysis	IEP	Enrichment
BP	GO:0006629	lipid metabolic process	IEP	Enrichment
BP	GO:0006631	fatty acid metabolic process	IEP	Enrichment
BP	GO:0006633	fatty acid biosynthetic process	IEP	Enrichment
BP	GO:0006644	phospholipid metabolic process	IEP	Enrichment
BP	GO:0006720	isoprenoid metabolic process	IEP	Enrichment
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Enrichment
BP	GO:0006754	ATP biosynthetic process	IEP	Enrichment
BP	GO:0006766	vitamin metabolic process	IEP	Enrichment
BP	GO:0006767	water-soluble vitamin metabolic process	IEP	Enrichment
BP	GO:0006793	phosphorus metabolic process	IEP	Enrichment
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Enrichment
BP	GO:0006811	ion transport	IEP	Enrichment
BP	GO:0006812	cation transport	IEP	Enrichment
BP	GO:0006996	organelle organization	IEP	Enrichment
BP	GO:0007059	chromosome segregation	IEP	Enrichment
MF	GO:0008094	ATPase, acting on DNA	IEP	Enrichment
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Enrichment
BP	GO:0008610	lipid biosynthetic process	IEP	Enrichment
BP	GO:0008614	pyridoxine metabolic process	IEP	Enrichment
BP	GO:0008615	pyridoxine biosynthetic process	IEP	Enrichment
BP	GO:0008654	phospholipid biosynthetic process	IEP	Enrichment
MF	GO:0008685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	IEP	Enrichment
MF	GO:0008964	phosphoenolpyruvate carboxylase activity	IEP	Enrichment
BP	GO:0009058	biosynthetic process	IEP	Enrichment
BP	GO:0009110	vitamin biosynthetic process	IEP	Enrichment
BP	GO:0009117	nucleotide metabolic process	IEP	Enrichment
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009143	nucleoside triphosphate catabolic process	IEP	Enrichment
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009165	nucleotide biosynthetic process	IEP	Enrichment
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Enrichment
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0009259	ribonucleotide metabolic process	IEP	Enrichment
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Enrichment
CC	GO:0009295	nucleoid	IEP	Enrichment
CC	GO:0009317	acetyl-CoA carboxylase complex	IEP	Enrichment
MF	GO:0015078	proton transmembrane transporter activity	IEP	Enrichment
MF	GO:0015252	proton channel activity	IEP	Enrichment
BP	GO:0015939	pantothenate metabolic process	IEP	Enrichment
BP	GO:0015940	pantothenate biosynthetic process	IEP	Enrichment
BP	GO:0015977	carbon fixation	IEP	Enrichment
BP	GO:0015985	energy coupled proton transport, down electrochemical gradient	IEP	Enrichment
BP	GO:0015986	ATP synthesis coupled proton transport	IEP	Enrichment
BP	GO:0016043	cellular component organization	IEP	Enrichment
BP	GO:0016053	organic acid biosynthetic process	IEP	Enrichment
MF	GO:0016421	CoA carboxylase activity	IEP	Enrichment
MF	GO:0016462	pyrophosphatase activity	IEP	Enrichment
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEP	Enrichment
MF	GO:0016787	hydrolase activity	IEP	Enrichment
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Enrichment
MF	GO:0016829	lyase activity	IEP	Enrichment
MF	GO:0016831	carboxy-lyase activity	IEP	Enrichment
MF	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	IEP	Enrichment
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Enrichment
MF	GO:0016853	isomerase activity	IEP	Enrichment
MF	GO:0016866	intramolecular transferase activity	IEP	Enrichment
MF	GO:0016885	ligase activity, forming carbon-carbon bonds	IEP	Enrichment
BP	GO:0018130	heterocycle biosynthetic process	IEP	Enrichment
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Enrichment
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Enrichment
BP	GO:0019637	organophosphate metabolic process	IEP	Enrichment
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Enrichment
BP	GO:0019693	ribose phosphate metabolic process	IEP	Enrichment
BP	GO:0030261	chromosome condensation	IEP	Enrichment
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Enrichment
CC	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain	IEP	Enrichment
MF	GO:0033856	pyridoxine 5'-phosphate synthase activity	IEP	Enrichment
BP	GO:0034220	ion transmembrane transport	IEP	Enrichment
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Enrichment
MF	GO:0035596	methylthiotransferase activity	IEP	Enrichment
BP	GO:0042364	water-soluble vitamin biosynthetic process	IEP	Enrichment
BP	GO:0042816	vitamin B6 metabolic process	IEP	Enrichment
BP	GO:0042819	vitamin B6 biosynthetic process	IEP	Enrichment
MF	GO:0042834	peptidoglycan binding	IEP	Enrichment
BP	GO:0044249	cellular biosynthetic process	IEP	Enrichment
BP	GO:0044255	cellular lipid metabolic process	IEP	Enrichment
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:0044283	small molecule biosynthetic process	IEP	Enrichment
CC	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)	IEP	Enrichment
BP	GO:0046034	ATP metabolic process	IEP	Enrichment
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Enrichment
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Enrichment
MF	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	IEP	Enrichment
MF	GO:0050497	alkylthioltransferase activity	IEP	Enrichment
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Enrichment
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Enrichment
BP	GO:0051276	chromosome organization	IEP	Enrichment
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEP	Enrichment
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Enrichment
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Enrichment
BP	GO:0071103	DNA conformation change	IEP	Enrichment
BP	GO:0071840	cellular component organization or biogenesis	IEP	Enrichment
BP	GO:0072330	monocarboxylic acid biosynthetic process	IEP	Enrichment
BP	GO:0072521	purine-containing compound metabolic process	IEP	Enrichment
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Enrichment
BP	GO:0090407	organophosphate biosynthetic process	IEP	Enrichment
BP	GO:0098655	cation transmembrane transport	IEP	Enrichment
BP	GO:0098660	inorganic ion transmembrane transport	IEP	Enrichment
BP	GO:0098662	inorganic cation transmembrane transport	IEP	Enrichment
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Enrichment
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Enrichment
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Enrichment
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Enrichment
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Enrichment
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Enrichment
BP	GO:1901576	organic substance biosynthetic process	IEP	Enrichment
BP	GO:1901617	organic hydroxy compound biosynthetic process	IEP	Enrichment
BP	GO:1902600	proton transmembrane transport	IEP	Enrichment

InterPro domains	Description	Start	Stop
IPR019499	Val-tRNA_synth_tRNA-bd	886	944
IPR002300	aa-tRNA-synth_Ia	14	631
IPR013155	M/V/L/I-tRNA-synth_anticd-bd	674	824

External Links

UniProtKB	P07118

AAC77215 (valS, b4258)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation